清肺化痰通腑方预防痰蒙清窍证脑卒中急性期肺部感染临床研究
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摘要
目的:探讨清肺化痰通腑汤在预防痰蒙清窍证脑卒中急性期肺部感染中的效果。方法:选择2014年3月-2015年12月我院神经内科收治的80名痰蒙清窍证脑卒中急性期患者,分为对照组和预防组,对照组给予常规的治疗和护理方法,预防组在对照组的基础上给予鼻饲清肺化痰通腑汤,在治疗1周或治疗期间出现肺部感染时,停止观察,比较两组患者实验室检查结果、中医症状评分以及治疗前后神经功能缺损评分情况。结果:预防组肺部感染的发生率(20.0%)明显低于对照组(45.0%),P<0.05,差异具有统计学意义。治疗后两组患者的神经功能缺损评分以及中医症候积分均出现明显的下降,P<0.05,差异具有统计学意义;与治疗后对照组相比,预防组患者神经功能缺损评分以及中医症候积分具有明显的优势,P<0.05,差异具有统计学意义。治疗后两组患者的CRP以及ESR指标呈现明显的升高趋势,P<0.05;与对照组治疗后相比,预防组各炎症指标升高的幅度较低,具有明显的优势,P<0.05,差异具有统计学意义。结论:针对痰蒙清窍证脑卒中急性期患者给予化痰通腑方治疗能够显著降低感染的发生,降低并发症,改善患者的预后情况,达到了中医"治未病"和"肺与大肠相表里"的理论要求。
Objective:To study the effect of the Qingfei Huatan Tongfu decoction on pulmonary infection in the acute stage of stroke.Methods:80 patients with acute phlegm-clearing syndrome were randomly divided into the control group and prevention group.The prevention group took the Qingfei Huatan Tongfu decoction more than the control group.Results:The incidence of pulmonary infection in the prevention group(20.0%) was significantly lower than that in the control group(45.0%),P<0.05.Compared with the control group,the neurological deficit score and TCM syndrome scores in the prevention group were significantly(P<0.05).Compared with the control group,the increase of the inflammation index in the prevention group was lower,with significant advantage(P<0.05).Conclusion:The Qingfei Huatan Tongfu decoction can reduce the occurrence of infection,reduce the complication and improve the prognosis.
Objective:To study the effect of the Qingfei Huatan Tongfu decoction on pulmonary infection in the acute stage of stroke.Methods:80 patients with acute phlegm-clearing syndrome were randomly divided into the control group and prevention group.The prevention group took the Qingfei Huatan Tongfu decoction more than the control group.Results:The incidence of pulmonary infection in the prevention group(20.0%) was significantly lower than that in the control group(45.0%),P<0.05.Compared with the control group,the neurological deficit score and TCM syndrome scores in the prevention group were significantly(P<0.05).Compared with the control group,the increase of the inflammation index in the prevention group was lower,with significant advantage(P<0.05).Conclusion:The Qingfei Huatan Tongfu decoction can reduce the occurrence of infection,reduce the complication and improve the prognosis.
引文
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[2]谭诚,彭文宏,胡明秋,等.青年脑卒中急性期抑郁发生的相关因素分析[J].广东医学,2013,34(6):912-915.
[3]李元朋,许坚.脑卒中急性期运动疗法的体会[J].中国医师杂志,2015,23(z2):108-109.
[4]郎奕,邹忆怀.星蒌承气汤加减治疗脑卒中急性期的系统评价[J].中西医结合心脑血管病杂志,2014,25(11):1299-1305.
[5]郭葵兴.细节护理在脑卒中急性期动态血压监测中的应用[J].护理实践与研究,2014,13(7):59-59,60.
[6]邹素华,吴小青,郑秋霞,等.中西医结合护理在防治脑卒中急性期并发呼吸道感染中的应用[J].中国中医急症,2013,22(6):1081-1082.
[7]周东浩,张蕾,周爱明.肺与大肠相表里今释[J].中国中医基础医学杂志,2003,9(8):567.
[8]冯维斌,刘伟胜.通里攻下法在肺心病急性呼吸衰竭的应用[J].中国中医急症,1998,7(4):180.
[9]高萍.化痰通腑方治疗痰热腑实型脑梗死30例疗效观察[J].国医论坛,2008,23(4):21.
[10]贾淑丽.通腑泻肺汤治疗老年便秘并肺部感染60例疗效观察[J].中医临床研究,2014,6(19):59-60.