探讨不育男性体质量指数与精液质量间的相关性
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摘要
目的:分析男性不育与体质量指数(BMI)和精液质量间的相互关系。方法:选择本院2015年1月—2018年3月就诊的不育男性患者100例临床资料,参考中国成人BMI标准分为低体质量组(BMI<18.5kg/m~2)、正常组(18.50.05);精液中炎性因子(TNF-α和IL-6)与BMI呈正相关性, VEGF与BMI呈负相关性(P>0.05)。结论:男性BMI与精液质量存在一定关系,当BMI>28时,不育男性T、LH含量明显降低并影响精子活力,临床应引起重视。
Objective: To analyze the correlation between body mass index and semen quality of infertile men. Methods: 100 infertile men were selected as subjects from January 2015 to March 2018.According to the difference of body mass index(BMI), the included man were divided into group A(BMI<18.5), group B(18.530.0).All the man were measured the quality parameters of semen. The correlation between the BMI and the quality of semen were analyzed. Results: The level of estradiol(E_2) of man in group C or group D was significant higher than that of man in group A or group B, but the level of testosterone(T) were significant lower(P<0.05). The semen volume and total number of sperm of man in group B was highest by analyzing the median and quartile spacing of parameters of semen quality(P<0.05). There was no significant difference in the other parameters of residual semen quality among the four groups(P>0.05). Conclusion: There is a certain correlation between BMI of male body mass index and the quality of semen. When BMI is over 28, the level of T and LH reduce obviously, which can decrease the vitality of sperm.
Objective: To analyze the correlation between body mass index and semen quality of infertile men. Methods: 100 infertile men were selected as subjects from January 2015 to March 2018.According to the difference of body mass index(BMI), the included man were divided into group A(BMI<18.5), group B(18.5
引文
[1] Eisenberg ML,Kim S,Chen Z,et al. The relationship between male BMI and waist circumference on semen quality: Data from the LIFE study. Human Reproduction,2014,29(2):193-200.
[2] 白双勇,王剑松,赵庆华.不同体重指数男性不育患者促性腺激素及性激素水平研究.中国妇幼保健,2015,(14):2237-2240.
[3] Bieniek JM,Kashanian JA,Deibert CM,et al. Influence of in-creasing body mass index on semen and reproductive hormonal parameters in a multi-institutional cohort of subfertile men. Fertil Steril,2016,106(5):1070-1075.
[4] 孙立峰,杨雅莉,张键.肥胖引起的氧化应激及其对两性生殖的影响[J].公共卫生与预防医学,2015,26(4):71-73.
[5] 袁启龙,陆杉,卢兴宏,等.男性血清FSH/LH 及 T/LH 比值与精子主要参数相关性分析[J].临床检验杂志,2015,33(3):197-199.
[6] 孙立峰,杨雅莉,张键.肥胖引起的氧化应激及其对两性生殖的影响[J]. 公共卫生与预防医学,2015,26(4):71-73.
[7] 袁启龙,陆杉,卢兴宏,等.男性血清 FSH/LH 及 T/LH 比值与精子主要参数相关性分析[J].临床检验杂志,2015,33(3):197-199.
[8] 汤尤怡,马艳华. 肥胖与男性不育关系的研究进展[J]. 生殖医学杂志,2015,24(4):338-341.
[9] 于海涛 ,王舒然. 肥胖对男性生殖功能影响机制的探讨[J].吉林医药学院学报,2014,35(1):55-58.
[10] 朱治省 ,金辉华. 健康体检人群体质量指数与血压、血糖及血脂关系的研究[J]. 国际检验医学杂志,2014,35(7):936-937.
[11] Bieniek JM,Kashanian JA,Deibert CM,et al. Influence of in-creasing body mass index on semen and reproductive hormonal parameters in a multi-institutional cohort of subfertile men. Fertil Steril,2016,106(5):1070-1075.
[12] Campbell JM,Lane M,Owens JA,et al. Paternal obesity nega-tively affects male fertility and assisted reproduction outcomes: A systematic review and meta-analysis. Reprod Biomed Online,2015,31(5):593-604.
[13] Eisenberg ML,Kim S,Chen Z,et al. The relationship between male BMI and waist circumference on semen quality: Data from the LIFE study. Human Reproduction,2014,29(2):193-200.
[14] 白双勇,王剑松,赵庆华.不同体重指数男性不育患者促性腺激素及性激素水平研究. 中国妇幼保健,2015,(14) :2237-2240.
[15] Faure C,Dupont C,Baraibar MA,et al. In subfertile couple,abdominal fat loss in men is associated with improvement of sperm quality and pregnancy: A case-series. PLo S One,2014,9(2) :86300.
[2] 白双勇,王剑松,赵庆华.不同体重指数男性不育患者促性腺激素及性激素水平研究.中国妇幼保健,2015,(14):2237-2240.
[3] Bieniek JM,Kashanian JA,Deibert CM,et al. Influence of in-creasing body mass index on semen and reproductive hormonal parameters in a multi-institutional cohort of subfertile men. Fertil Steril,2016,106(5):1070-1075.
[4] 孙立峰,杨雅莉,张键.肥胖引起的氧化应激及其对两性生殖的影响[J].公共卫生与预防医学,2015,26(4):71-73.
[5] 袁启龙,陆杉,卢兴宏,等.男性血清FSH/LH 及 T/LH 比值与精子主要参数相关性分析[J].临床检验杂志,2015,33(3):197-199.
[6] 孙立峰,杨雅莉,张键.肥胖引起的氧化应激及其对两性生殖的影响[J]. 公共卫生与预防医学,2015,26(4):71-73.
[7] 袁启龙,陆杉,卢兴宏,等.男性血清 FSH/LH 及 T/LH 比值与精子主要参数相关性分析[J].临床检验杂志,2015,33(3):197-199.
[8] 汤尤怡,马艳华. 肥胖与男性不育关系的研究进展[J]. 生殖医学杂志,2015,24(4):338-341.
[9] 于海涛 ,王舒然. 肥胖对男性生殖功能影响机制的探讨[J].吉林医药学院学报,2014,35(1):55-58.
[10] 朱治省 ,金辉华. 健康体检人群体质量指数与血压、血糖及血脂关系的研究[J]. 国际检验医学杂志,2014,35(7):936-937.
[11] Bieniek JM,Kashanian JA,Deibert CM,et al. Influence of in-creasing body mass index on semen and reproductive hormonal parameters in a multi-institutional cohort of subfertile men. Fertil Steril,2016,106(5):1070-1075.
[12] Campbell JM,Lane M,Owens JA,et al. Paternal obesity nega-tively affects male fertility and assisted reproduction outcomes: A systematic review and meta-analysis. Reprod Biomed Online,2015,31(5):593-604.
[13] Eisenberg ML,Kim S,Chen Z,et al. The relationship between male BMI and waist circumference on semen quality: Data from the LIFE study. Human Reproduction,2014,29(2):193-200.
[14] 白双勇,王剑松,赵庆华.不同体重指数男性不育患者促性腺激素及性激素水平研究. 中国妇幼保健,2015,(14) :2237-2240.
[15] Faure C,Dupont C,Baraibar MA,et al. In subfertile couple,abdominal fat loss in men is associated with improvement of sperm quality and pregnancy: A case-series. PLo S One,2014,9(2) :86300.