无创正压通气治疗慢性阻塞性肺疾病合并呼吸衰竭的临床效果
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摘要
目的分析无创正压通气治疗慢性阻塞性肺疾病合并呼吸衰竭的临床效果。方法选取2016年9月～2017年12月我院收治的120例慢性阻塞性肺疾病合并呼吸衰竭的患者作为研究对象,随机分为观察组和对照组,每组各60例。对照组患者采用常规方案治疗,观察组患者在常规治疗的基础上加入无创通气治疗,比较两组患者的临床效果。结果观察组患者的治疗总有效率高于对照组,差异有统计学意义(P<0.05);两组患者治疗前的动脉血氧分压(PaO2)、二氧化碳分压(PaCO2)、呼吸频率、心率比较,差异无统计学意义(P>0.05);治疗后,观察组的PaO2明显高于对照组, PaCO2、呼吸以及心率均低于对照组,差异有统计学意义(P<0.05);观察组患者的生活质量评分高于对照组,住院时间短于对照组,差异有统计学意义(P<0.05)。结论对于慢性阻塞性肺疾病合并呼吸衰竭的患者采用无创正压通气治疗的效果较为理想,可以有效改善患者的相关指标,提高生活质量,保证患者的健康。
Objective To analyze the clinical effect of noninvasive positive pressure ventilation(NIPPV) in the treatment of chronic obstructive pulmonary disease(COPD) with respiratory failure(RF). Methods A total of 120 patients with COPD and RF admitted to our hospital from September 2016 to December 2017 were selected as study subjects.They were randomly divided into observation group and control group, with 60 cases in each group. In the control group, conventional regimen was used, while in the observation group, NIPPV was added on the basis of conventional treatment. The clinical efficacy of the two groups were compared. Results The total effective rate of the observation group was significantly higher than that of the control group, with a significant difference(P<0.05). There was no significant difference in PaO2, PaCO2, respiratory rate or heart rate between the two groups before treatment(P>0.05). After treatment, the PaO2 of the observation group was significantly higher than that of the control group. The PaCO2, respiratory rate, and heart rate were significantly lower than those of the control group, with statistical differences(P <0.05). At the same time, the quality of life scores of the observation group were higher than those of the control group.The hospital stay was significantly shorter than that of the control group, with a significant difference(P<0.05). Conclusion For patients with COPD and RF, NIPPV can obtain a satisfactory effect. It can effectively improve the relevant indicators of patients as well as the quality of life, and ensure patient′s health.
Objective To analyze the clinical effect of noninvasive positive pressure ventilation(NIPPV) in the treatment of chronic obstructive pulmonary disease(COPD) with respiratory failure(RF). Methods A total of 120 patients with COPD and RF admitted to our hospital from September 2016 to December 2017 were selected as study subjects.They were randomly divided into observation group and control group, with 60 cases in each group. In the control group, conventional regimen was used, while in the observation group, NIPPV was added on the basis of conventional treatment. The clinical efficacy of the two groups were compared. Results The total effective rate of the observation group was significantly higher than that of the control group, with a significant difference(P<0.05). There was no significant difference in PaO2, PaCO2, respiratory rate or heart rate between the two groups before treatment(P>0.05). After treatment, the PaO2 of the observation group was significantly higher than that of the control group. The PaCO2, respiratory rate, and heart rate were significantly lower than those of the control group, with statistical differences(P <0.05). At the same time, the quality of life scores of the observation group were higher than those of the control group.The hospital stay was significantly shorter than that of the control group, with a significant difference(P<0.05). Conclusion For patients with COPD and RF, NIPPV can obtain a satisfactory effect. It can effectively improve the relevant indicators of patients as well as the quality of life, and ensure patient′s health.
引文
[1]刘英姿,王东升,杨冠英,等.无创正压通气治疗COPD并呼吸衰竭的临床疗效[J].影像研究与医学应用,2018,2(4):219-220.
[2]刘英杰.探讨无创正压通气治疗慢性阻塞性肺疾病(COPD)急性加重期并Ⅱ型呼吸衰竭的临床效果[J].中国医药指南,2018,16(1):83-84.
[3]吴忠军,唐剑,周魁.无创正压通气治疗老年慢性阻塞性肺疾病合并重症呼吸衰竭的临床效果[J].中国当代医药,2018,25(11):41-43.
[4]石彩丽,汶小红.COPD合并Ⅱ型呼吸衰竭采取综合护理干预对无创正压通气治疗效果的影响[J].临床医学研究与实践,2018,3(4):160-161.
[5]卫晓泽.丙酸氟替卡松联合无创正压通气治疗COPD的临床疗效及对患者肺功能的影响[J].临床医药文献电子杂志,2018,5(5):187.
[6]郭平,史瑞峰,王晓平,等.无创呼吸机治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者的临床疗效[J].中国现代医生,2018,56(28):105-107.
[7]牛立君.无创正压通气治疗COPD合并Ⅱ型呼吸衰竭的临床疗效分析[J].世界最新医学信息文摘,2017,17(21):15.
[8]胡晨虎,沈利,叶天航,等.无创正压通气治疗老年COPD重症呼吸衰竭患者的临床应用效果[J].中西医结合心血管病电子杂志,2018,6(15):167,170.
[9]冯莉,杜泽慧,阿依努尔,等.无创正压通气治疗COPD并呼吸衰竭的临床疗效探讨[J].当代医学,2017,23(4):98-99.
[10]郑萍.无创正压通气治疗COPD并呼吸衰竭的临床疗效[J].中国保健营养,2016,26(16):75-76.
[11]楚文丽,宋立强,严蕊娜,等.舒利迭联合无创正压通气治疗COPD合并呼吸衰竭的临床疗效观察[J].现代生物医学进展,2017,17(23):4483-4486.
[12]苏霞,罗马长.无创正压通气治疗COPD并呼吸衰竭的临床疗效观察[J].临床合理用药杂志,2017,10(19):123-124.
[13]刘林.无创通气治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭的临床观察[J].中外医学研究,2017,15(32):30-32.
[14]张艳,林承奎,赵祥玲,等.无创正压通气治疗COPD合并呼吸衰竭的临床疗效[J].中国陶瓷工业,2016,26(5):31-34.
[15]刘君君,卢经伟.无创正压通气治疗COPD合并呼吸衰竭患者的疗效观察[J].临床肺科杂志,2014,19(4):746-747.
[2]刘英杰.探讨无创正压通气治疗慢性阻塞性肺疾病(COPD)急性加重期并Ⅱ型呼吸衰竭的临床效果[J].中国医药指南,2018,16(1):83-84.
[3]吴忠军,唐剑,周魁.无创正压通气治疗老年慢性阻塞性肺疾病合并重症呼吸衰竭的临床效果[J].中国当代医药,2018,25(11):41-43.
[4]石彩丽,汶小红.COPD合并Ⅱ型呼吸衰竭采取综合护理干预对无创正压通气治疗效果的影响[J].临床医学研究与实践,2018,3(4):160-161.
[5]卫晓泽.丙酸氟替卡松联合无创正压通气治疗COPD的临床疗效及对患者肺功能的影响[J].临床医药文献电子杂志,2018,5(5):187.
[6]郭平,史瑞峰,王晓平,等.无创呼吸机治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者的临床疗效[J].中国现代医生,2018,56(28):105-107.
[7]牛立君.无创正压通气治疗COPD合并Ⅱ型呼吸衰竭的临床疗效分析[J].世界最新医学信息文摘,2017,17(21):15.
[8]胡晨虎,沈利,叶天航,等.无创正压通气治疗老年COPD重症呼吸衰竭患者的临床应用效果[J].中西医结合心血管病电子杂志,2018,6(15):167,170.
[9]冯莉,杜泽慧,阿依努尔,等.无创正压通气治疗COPD并呼吸衰竭的临床疗效探讨[J].当代医学,2017,23(4):98-99.
[10]郑萍.无创正压通气治疗COPD并呼吸衰竭的临床疗效[J].中国保健营养,2016,26(16):75-76.
[11]楚文丽,宋立强,严蕊娜,等.舒利迭联合无创正压通气治疗COPD合并呼吸衰竭的临床疗效观察[J].现代生物医学进展,2017,17(23):4483-4486.
[12]苏霞,罗马长.无创正压通气治疗COPD并呼吸衰竭的临床疗效观察[J].临床合理用药杂志,2017,10(19):123-124.
[13]刘林.无创通气治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭的临床观察[J].中外医学研究,2017,15(32):30-32.
[14]张艳,林承奎,赵祥玲,等.无创正压通气治疗COPD合并呼吸衰竭的临床疗效[J].中国陶瓷工业,2016,26(5):31-34.
[15]刘君君,卢经伟.无创正压通气治疗COPD合并呼吸衰竭患者的疗效观察[J].临床肺科杂志,2014,19(4):746-747.