探讨藏药二十五味松石丸的配伍特点及其治疗肝病的核心组合成分
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摘要
目的:通过初步了解二十五味松石丸的配伍特点及其治疗肝病的核心组合成分,以期为藏药方剂组方的优化及新药研发提供思路与方法。方法:本研究通过查阅《四部医典》、《新修晶珠本草》等藏医药典籍,概括二十五味松石丸中所含25味药的"味"、"性效"并分析二十五味松石丸的药"味"、"性效"的配伍特点,整理出21种常用治疗肝病的藏药方剂,统计二十五味松石丸的各成分药在21种常用治疗肝病藏药方剂中单味药的使用频次和药对配伍频次,并进行分析。结论:结果表明,二十五味松石丸是以清热药配伍为主的组方,主要治疗热性肝病,其核心组合成分为西红花和牛黄。
Objective: To explore the core composition and compatibility features of Ershiwuwei Songshi pills in the treatment of liver disease, in order to provide ideas and methods for the optimization of Tibetan medicine prescriptions and the creation of new medicine. Methods: In this study, I checked common prescriptions for the treatment of liver diseases from the Tibetan Medical Classics, such as Four Medical Classics, Xin Xiu Jing Zhu Ben Cao, etc., summarizing the flavor, nature and efficacy of the 25 herbs in Ershiwuwei Songshi pill, and analyzing the compatibility features of flavor and of nature and efficacy of the 25 herbs in Ershiwuwei Songshi pill. And I also sorted out 21 common prescriptions for the treatment of liver diseases in the Tibetan Medical formula, counting and analyzing the using frequency of the ingredient medicine of Ershiwuwei Songshi pill in the 21 Tibetan medical formula for the treatment of liver and the compatibility frequency. Conclusion: The results show that Ershiwuwei Songshi pills are composed of a heat clearing formula, mainly for the treatment of heat liver diseases.
Objective: To explore the core composition and compatibility features of Ershiwuwei Songshi pills in the treatment of liver disease, in order to provide ideas and methods for the optimization of Tibetan medicine prescriptions and the creation of new medicine. Methods: In this study, I checked common prescriptions for the treatment of liver diseases from the Tibetan Medical Classics, such as Four Medical Classics, Xin Xiu Jing Zhu Ben Cao, etc., summarizing the flavor, nature and efficacy of the 25 herbs in Ershiwuwei Songshi pill, and analyzing the compatibility features of flavor and of nature and efficacy of the 25 herbs in Ershiwuwei Songshi pill. And I also sorted out 21 common prescriptions for the treatment of liver diseases in the Tibetan Medical formula, counting and analyzing the using frequency of the ingredient medicine of Ershiwuwei Songshi pill in the 21 Tibetan medical formula for the treatment of liver and the compatibility frequency. Conclusion: The results show that Ershiwuwei Songshi pills are composed of a heat clearing formula, mainly for the treatment of heat liver diseases.
引文
1孙方云,徐世林,张召腾,等.藏药二十五味松石丸对大鼠内毒素血症的保护作用.中药药理与临床, 2015, 31(1):190-192.
2 张春江,李红玉,贡布,等.藏药复方二十五味松石丸体外抑菌作用的研究.中成药, 2007, 29(10):1534-1536.
3 张洁,熊万里,袁东亚,等.藏药二十五味松石丸对家兔内毒素性肝损伤保护作用的研究.中国实验方剂学杂志, 2016, 22(19):116-120.
4 张喜民,张怡沛,赵良功.二十五味松石丸的质量标准研究.中成药,2009, 31(5):815-816.
5 张成玉,莫庆智.藏药二十五味松石丸治疗慢性胆囊炎60例临床疗效观察.中国民族医药杂志, 2016, 1:17-18.
6 才旦吉,却张.浅谈藏医治疗病毒性肝炎.临床医药实践杂志, 2009,18(33):879.
7 马永祥,朵德祥.二十五味松石丸治疗病毒性肝炎的随机对照临床研究.中国临床药理学杂志, 2010, 26(11):807-809.
8 宇妥云丹贡布.四部医典.拉萨:西藏人民出版社, 1982:299-302.
9 罗达尚.新修晶珠本草.成都:四川科学技术出版社, 2004:47-802.
10 毛韶玲.藏药与方剂.兰州:甘肃民族出版社, 2001:1-175.
11 索朗顿珠.藏汉合璧常用藏成药使用手册.北京:民族出版社, 2006:303.
12 普琼次仁.传统藏药配方的独特性理论研究, 2011:1-50.
13 帝玛尔·丹增彭措.晶珠本草.上海科学技术出版社, 1986:1-100.
14 毗如赞纳,马哈金达等编译:《月王药诊》(藏文),北京:民族出版社,2006:1-140.
15 龙本塔,米玛.浅谈藏药配方中咔擦的认识及应用.中国民族医药杂志, 2017, 5:36-37.
16 邱建智.藏药学基础理论与方剂配伍规律的探析.西部中医药,2013, 26(1):64-67.
17 宋佳,高晓霞,田俊生,等.中药药对配伍机制的现代研究.中草药,2017, 48(21):4367-4374.
18 王曼华,孙化萍,梁建卫.经方“药对”配伍理论研究概况.辽宁中医药大学学报, 2008,1 0(1):59-60.
19 孙洋,陈婷,徐强.从药对的角度考察复方配伍规律.世界科学技术-中医药现代化,2004, 6(1):17-20.
20 才让南加,仁增多杰.基于数据挖掘的藏族医学四部医典治疗热性肝病方剂配伍规律.中国实验方剂学杂志, 2015, 21(10):216-219.
21 西珠嘉措.略论藏医对肝和肝病的认识.中国藏学, 2010, 4:155-158.
2 张春江,李红玉,贡布,等.藏药复方二十五味松石丸体外抑菌作用的研究.中成药, 2007, 29(10):1534-1536.
3 张洁,熊万里,袁东亚,等.藏药二十五味松石丸对家兔内毒素性肝损伤保护作用的研究.中国实验方剂学杂志, 2016, 22(19):116-120.
4 张喜民,张怡沛,赵良功.二十五味松石丸的质量标准研究.中成药,2009, 31(5):815-816.
5 张成玉,莫庆智.藏药二十五味松石丸治疗慢性胆囊炎60例临床疗效观察.中国民族医药杂志, 2016, 1:17-18.
6 才旦吉,却张.浅谈藏医治疗病毒性肝炎.临床医药实践杂志, 2009,18(33):879.
7 马永祥,朵德祥.二十五味松石丸治疗病毒性肝炎的随机对照临床研究.中国临床药理学杂志, 2010, 26(11):807-809.
8 宇妥云丹贡布.四部医典.拉萨:西藏人民出版社, 1982:299-302.
9 罗达尚.新修晶珠本草.成都:四川科学技术出版社, 2004:47-802.
10 毛韶玲.藏药与方剂.兰州:甘肃民族出版社, 2001:1-175.
11 索朗顿珠.藏汉合璧常用藏成药使用手册.北京:民族出版社, 2006:303.
12 普琼次仁.传统藏药配方的独特性理论研究, 2011:1-50.
13 帝玛尔·丹增彭措.晶珠本草.上海科学技术出版社, 1986:1-100.
14 毗如赞纳,马哈金达等编译:《月王药诊》(藏文),北京:民族出版社,2006:1-140.
15 龙本塔,米玛.浅谈藏药配方中咔擦的认识及应用.中国民族医药杂志, 2017, 5:36-37.
16 邱建智.藏药学基础理论与方剂配伍规律的探析.西部中医药,2013, 26(1):64-67.
17 宋佳,高晓霞,田俊生,等.中药药对配伍机制的现代研究.中草药,2017, 48(21):4367-4374.
18 王曼华,孙化萍,梁建卫.经方“药对”配伍理论研究概况.辽宁中医药大学学报, 2008,1 0(1):59-60.
19 孙洋,陈婷,徐强.从药对的角度考察复方配伍规律.世界科学技术-中医药现代化,2004, 6(1):17-20.
20 才让南加,仁增多杰.基于数据挖掘的藏族医学四部医典治疗热性肝病方剂配伍规律.中国实验方剂学杂志, 2015, 21(10):216-219.
21 西珠嘉措.略论藏医对肝和肝病的认识.中国藏学, 2010, 4:155-158.