癫痫中西医治疗研究概况
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摘要
癫痫,人类第二大神经系统疾病,严重影响着人们的工作、学习、生活质量。临床上治疗癫痫的方法很多,并都取得了一定的疗效。西医治疗癫痫的措施包含病因治疗、抗癫痫药物治疗以及非药物治疗;中医主要包括方药、针灸、针药联合和穴位埋线等综合疗法。现分析、概括、总结我国中西医治疗癫痫的方法,为临床医师治疗癫痫提供一些借鉴。
Epilepsy,the second largest neurological disease in humans,seriously affects people's work,study,and quality of life. There are many methods for the treatment of epilepsy in clinical practice,and all have achieved certain effects. Western medicine treatment of epilepsy includes etiological treatment,antiepileptic drug treatment and non-drug treatment;Chinese medicine mainly includes prescription medicine,acupuncture,acupuncture combined with acupoint embedding and other comprehensive treatment. Now analyze,summarize and summarize the methods of Chinese and Western medicine for the treatment of epilepsy,and provide some reference for clinicians to treat epilepsy.
Epilepsy,the second largest neurological disease in humans,seriously affects people's work,study,and quality of life. There are many methods for the treatment of epilepsy in clinical practice,and all have achieved certain effects. Western medicine treatment of epilepsy includes etiological treatment,antiepileptic drug treatment and non-drug treatment;Chinese medicine mainly includes prescription medicine,acupuncture,acupuncture combined with acupoint embedding and other comprehensive treatment. Now analyze,summarize and summarize the methods of Chinese and Western medicine for the treatment of epilepsy,and provide some reference for clinicians to treat epilepsy.
引文
[1]Limei Diao,Haichun Yu,Jinou Zheng,et al. Abnormalities of the uncinate fasciculus correlate with executive dysfunction in patients with left temporal lobe epilepsy[J]. Magnetic Resonance Imaging,2015,33(5):544-550.
[2]Singh A,Trevick S. The epidemiology of global epilepsy[J].Neurol Clin,2016,34(4):837-884.
[3]杨华俊,郭安臣,王群.癫痫的发病机制研究进展[J].科技导报,2017,35(4):54-59.
[4]中华医学会.临床诊疗指南·癫痫病分册[M].北京:人民卫生出版社,2015:11-70.
[5]Thurman D J,Beghi E,Begley C E,et al. Standards for epidemiologic studies and surveillance of epilepsy[J].Epilepsia,2011,52(S7):2-26.
[6]Torbic H,Forni A A,Anger K E,et al. Use of antiepi-leptics for seizure prophylaxis after traumatic brain injury[J].American Journal of Health-System Pharmacy,2013,70(9):759-766.
[7]薛艳玲.传统与新型抗癫痫药物治疗新诊断癫痫患者的一年保留率比较[J].临床医药文献电子杂志,2017,4(92):18173-18174.
[8]梁树立.癫痫外科诊治新进展[J].中华医学信息导报,2015,30(4):5-6.
[9]张文浩,张波,别红军,等.难治性癫痫诊断治疗进展[J].中医药临床杂志,2013,25(3):269-273.
[10]陶裕川.难治性癫痫手术治疗效果及影响因素[J].局解手术学杂志,2014,23(1):82-83,88.
[11]林久銮,孙朝晖,张冰清,等.迷走神经刺激术治疗难治性癫痫(附25例报告)[J].临床神经外科杂志,2016,13(6):415-418,423.
[12]McHugh JC,Singh HW,Phillips J,et al. Outcome measurement after vagal nerve stimulation therapy:proposal of a new classification[J].Epilepsia,2007,48:375-378.
[13]赖其伦,丁美萍.迷走神经刺激治疗难治性癫痫的研究进展[J].现代实用医学,2017,29(4):423-424.
[14]王永才,金河天,贾成武.伽玛刀治疗颞叶内侧癫痫疗效及并发症评估[J].中华神经外科疾病研究杂志,2016,15(1):75-76.
[15]GummadavelliA,KundishoraAJ,WillieJF,etal.Neurostimulation to improve level of consciousness in patients with epilepsy[J].Neurosurg Focus,2015,38:E10.
[16]白春艳.神经调控治疗特发性癫痫临床疗效观察[J].中外医疗,2013,33(30):72-74.
[17]Fridley J,Thomas JG,Navarro JC. Brain stimulation for the treatment of epilepsy[J].Neurosurgical focus,2012,32(3):E13.
[18]范文斐,刘献志.脑深部电刺激在药物难治性癫痫中的应用[J].临床神经外科杂志,2017,14(6):475-478.
[19]廖建湘.生酮饮食疗法在难治性癫痫中的应用[J].中国实用儿科杂志,2016,31(1):41-45.
[20]Suo C,Liao J,Lu X,et al. Efficacy and safety of the ketogenic diet in Chinese children[J].Seizure,2013,22(3):174-178.
[21]郭改艳,董治燕.癫痫患者脑脊液和血清中miRNA-184的表达[J].实用临床医药杂志,2015,19(1):142-144.
[22]Howell OW,Scharfman HE,Herzog H,et al. Neuropeptide Y is neuroproliferative for post-natal hippocampal precursor cells[J].Journal of neurochemistry,2003,86(3):646-659.
[23]笱玉兰,张静,陈春鹏,等.定痫汤加味治疗风痰闭阻证耐药性癫痫的临床研究[J].中西医结合心脑血管病杂志,2017,15(16):1963-1965.
[24]李胜才.柴桂温胆定志汤加减治疗癫痫33例临床观察[J].中国民族民间医药,2016,25(11):83-84.
[25]耿玉娜.柴胡疏肝汤治疗癫痫临床观察[J].亚太传统医药,2015,11(19):135-136.
[26]王永安.通窍活血汤在脑卒中合并早发性癫痫持续状态治疗中的效果观察[J].中外医学研究,2017,15(23):23-24.
[27]王国富.六君子汤加减治疗顽固性癫痫[J].大家健康(学术版),2013,7(4):35.
[28]姜迎萍,刘浩,徐平.从功能磁共振成像技术探讨针灸足三里的中枢作用机制[J].四川中医,2007(1):98-101.
[29]刘卫英,彭楚湘.针刺治疗癲痫的实验研究进展[J].湖南中医学院学报,2006(1):62-63.
[30]孙宇丹,刘毅.癫痫中医辨证论治及针药治疗研究[J].中西医结合心脑血管病杂志,2016(17):2007-2010.
[31]陈杰奎.针刺促进大脑神经发育与修复的新进展[C]//中华中医药学会儿科分会.中华中医药学会儿科分会第三十一次学术大会论文汇编.北京:中华中医药学会儿科分会,2014:6.
[32]朱英鹏.针刺督脉穴位对中风后癫痫治疗作用的临床疗效观察[D].哈尔滨:黑龙江中医药大学,2015.
[33]黄广鹏.针刺联合豁痰息痉汤对脑梗死合并癫痫患者神经功能的影响[J].中外女性健康研究,2016(18):184-185.
[34]金泽,蔡硕,侯鑫磊,等.穴位埋线配合西药治疗癫痫大发作临床观察[J].上海针灸杂志,2017,36(10):1196-1198.
[35]史红斐,张侃,谢文霞,等.穴位埋线结合药物治疗难治性癫痫30例疗效观察[J].浙江中医杂志,2017,52(8):607.
[36]王煜斐.中西医结合抗痫综合方案治疗癫痫的临床效果观察[J].深圳中西医结合杂志,2017,27(4):23-24.
[37]林岚,梅茸,王晓燕,等.中西医结合治疗脑梗死后继发癫痫的临床疗效分析[J].辽宁中医杂志,2017,44(9):1924-1926.
[2]Singh A,Trevick S. The epidemiology of global epilepsy[J].Neurol Clin,2016,34(4):837-884.
[3]杨华俊,郭安臣,王群.癫痫的发病机制研究进展[J].科技导报,2017,35(4):54-59.
[4]中华医学会.临床诊疗指南·癫痫病分册[M].北京:人民卫生出版社,2015:11-70.
[5]Thurman D J,Beghi E,Begley C E,et al. Standards for epidemiologic studies and surveillance of epilepsy[J].Epilepsia,2011,52(S7):2-26.
[6]Torbic H,Forni A A,Anger K E,et al. Use of antiepi-leptics for seizure prophylaxis after traumatic brain injury[J].American Journal of Health-System Pharmacy,2013,70(9):759-766.
[7]薛艳玲.传统与新型抗癫痫药物治疗新诊断癫痫患者的一年保留率比较[J].临床医药文献电子杂志,2017,4(92):18173-18174.
[8]梁树立.癫痫外科诊治新进展[J].中华医学信息导报,2015,30(4):5-6.
[9]张文浩,张波,别红军,等.难治性癫痫诊断治疗进展[J].中医药临床杂志,2013,25(3):269-273.
[10]陶裕川.难治性癫痫手术治疗效果及影响因素[J].局解手术学杂志,2014,23(1):82-83,88.
[11]林久銮,孙朝晖,张冰清,等.迷走神经刺激术治疗难治性癫痫(附25例报告)[J].临床神经外科杂志,2016,13(6):415-418,423.
[12]McHugh JC,Singh HW,Phillips J,et al. Outcome measurement after vagal nerve stimulation therapy:proposal of a new classification[J].Epilepsia,2007,48:375-378.
[13]赖其伦,丁美萍.迷走神经刺激治疗难治性癫痫的研究进展[J].现代实用医学,2017,29(4):423-424.
[14]王永才,金河天,贾成武.伽玛刀治疗颞叶内侧癫痫疗效及并发症评估[J].中华神经外科疾病研究杂志,2016,15(1):75-76.
[15]GummadavelliA,KundishoraAJ,WillieJF,etal.Neurostimulation to improve level of consciousness in patients with epilepsy[J].Neurosurg Focus,2015,38:E10.
[16]白春艳.神经调控治疗特发性癫痫临床疗效观察[J].中外医疗,2013,33(30):72-74.
[17]Fridley J,Thomas JG,Navarro JC. Brain stimulation for the treatment of epilepsy[J].Neurosurgical focus,2012,32(3):E13.
[18]范文斐,刘献志.脑深部电刺激在药物难治性癫痫中的应用[J].临床神经外科杂志,2017,14(6):475-478.
[19]廖建湘.生酮饮食疗法在难治性癫痫中的应用[J].中国实用儿科杂志,2016,31(1):41-45.
[20]Suo C,Liao J,Lu X,et al. Efficacy and safety of the ketogenic diet in Chinese children[J].Seizure,2013,22(3):174-178.
[21]郭改艳,董治燕.癫痫患者脑脊液和血清中miRNA-184的表达[J].实用临床医药杂志,2015,19(1):142-144.
[22]Howell OW,Scharfman HE,Herzog H,et al. Neuropeptide Y is neuroproliferative for post-natal hippocampal precursor cells[J].Journal of neurochemistry,2003,86(3):646-659.
[23]笱玉兰,张静,陈春鹏,等.定痫汤加味治疗风痰闭阻证耐药性癫痫的临床研究[J].中西医结合心脑血管病杂志,2017,15(16):1963-1965.
[24]李胜才.柴桂温胆定志汤加减治疗癫痫33例临床观察[J].中国民族民间医药,2016,25(11):83-84.
[25]耿玉娜.柴胡疏肝汤治疗癫痫临床观察[J].亚太传统医药,2015,11(19):135-136.
[26]王永安.通窍活血汤在脑卒中合并早发性癫痫持续状态治疗中的效果观察[J].中外医学研究,2017,15(23):23-24.
[27]王国富.六君子汤加减治疗顽固性癫痫[J].大家健康(学术版),2013,7(4):35.
[28]姜迎萍,刘浩,徐平.从功能磁共振成像技术探讨针灸足三里的中枢作用机制[J].四川中医,2007(1):98-101.
[29]刘卫英,彭楚湘.针刺治疗癲痫的实验研究进展[J].湖南中医学院学报,2006(1):62-63.
[30]孙宇丹,刘毅.癫痫中医辨证论治及针药治疗研究[J].中西医结合心脑血管病杂志,2016(17):2007-2010.
[31]陈杰奎.针刺促进大脑神经发育与修复的新进展[C]//中华中医药学会儿科分会.中华中医药学会儿科分会第三十一次学术大会论文汇编.北京:中华中医药学会儿科分会,2014:6.
[32]朱英鹏.针刺督脉穴位对中风后癫痫治疗作用的临床疗效观察[D].哈尔滨:黑龙江中医药大学,2015.
[33]黄广鹏.针刺联合豁痰息痉汤对脑梗死合并癫痫患者神经功能的影响[J].中外女性健康研究,2016(18):184-185.
[34]金泽,蔡硕,侯鑫磊,等.穴位埋线配合西药治疗癫痫大发作临床观察[J].上海针灸杂志,2017,36(10):1196-1198.
[35]史红斐,张侃,谢文霞,等.穴位埋线结合药物治疗难治性癫痫30例疗效观察[J].浙江中医杂志,2017,52(8):607.
[36]王煜斐.中西医结合抗痫综合方案治疗癫痫的临床效果观察[J].深圳中西医结合杂志,2017,27(4):23-24.
[37]林岚,梅茸,王晓燕,等.中西医结合治疗脑梗死后继发癫痫的临床疗效分析[J].辽宁中医杂志,2017,44(9):1924-1926.