uMI 780 PET/CT NEMA性能指标测试研究
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摘要
目的对uMI 780 PET/CT性能指标进行测试研究。方法依据国家标准GB18988-1(NEMA NU2-2007)对PET空间分辨率、灵敏度、等效噪声计数率、散射分数、符合计数率等指标进行测试。结果视野中心1 cm处横向和轴向空间分辨率分别为3.11、3.17 mm,10 cm处分别为3.33、3.31 mm。视野中心和轴向10 cm处系统灵敏度分别为15.327、15.812 kcps/MBq。当放射源活度αpeak=17.81 kBq/cc时,等效噪声计数率取得峰值Rpeak=182.16 kcps,此时对应的散射分数SF=37.69%,低活度时的散射分数SF=36.89%;真符合计数率峰值Tpeak=563.04 kcps,对应的活度αpeak=31.55 kBq/cc。结论本研究采用的测试方法科学有效,受检测的PET各项性能指标均达到国家标准,为PET设备验收和质量控制提供技术依据。
Objective To quantitatively evaluate the performance index of uMI 780 PET/CT. Methods We measured the spatial resolution, sensitivity, noise equivalent count rate, scatter fraction and true coincidence count rate of PET according to GB18988-1(NEMA NU2-2007) standard. Results The horizontal spatial resolution and axial spatial resolution at 1 cm from center of field of view(FOV) were 3.11 and 3.17 mm, and they were 3.33 and 3.31 mm at 10 cm, respectively. The system sensitivities at center of FOV and 10 cm from center of FOV were 15.327 and 15.812 kcps/MBq, respectively. The peak value of noise equivalent counting rate was 182.16 kcps, when the radiation concentration was 17.81 kBq/cc. In addition, the scatter fraction was 37.69% at NECR peak and 36.89% at low activity. Meanwhile the largest real coincidence counting rate was 563.04 kcps, when the activity was 31.55 kBq/cc. Conclusion The method adopted by this study was scientifically feasible, the indexes of this PET are all up to national existing standards, which can provide reference for PET acceptance tests and quality control.
Objective To quantitatively evaluate the performance index of uMI 780 PET/CT. Methods We measured the spatial resolution, sensitivity, noise equivalent count rate, scatter fraction and true coincidence count rate of PET according to GB18988-1(NEMA NU2-2007) standard. Results The horizontal spatial resolution and axial spatial resolution at 1 cm from center of field of view(FOV) were 3.11 and 3.17 mm, and they were 3.33 and 3.31 mm at 10 cm, respectively. The system sensitivities at center of FOV and 10 cm from center of FOV were 15.327 and 15.812 kcps/MBq, respectively. The peak value of noise equivalent counting rate was 182.16 kcps, when the radiation concentration was 17.81 kBq/cc. In addition, the scatter fraction was 37.69% at NECR peak and 36.89% at low activity. Meanwhile the largest real coincidence counting rate was 563.04 kcps, when the activity was 31.55 kBq/cc. Conclusion The method adopted by this study was scientifically feasible, the indexes of this PET are all up to national existing standards, which can provide reference for PET acceptance tests and quality control.
引文
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[2]宋颖,刘辉.应用NEMA标准测试Discovery PET/CT690的性能[J].中国辐射卫生,2016,25(6):724-729.
[3]刘家金,刘猛,姚树林,等.一体化PET-MR中PET设备性能指标测试研究[J].中国医学装备,2018,15(4):13-17.
[4]Rausch I,Cal-González J,Dapra D,et al.Performance evaluation of the Biograph mCT Flow PET/CT system according to the NEMA NU2-2012 standard[J].Ejnm Phys,2015,2(1):1-17.
[5]Susanne Z,Jakoby BW,Harald B,et al.NEMA image quality phantom measurements and attenuation correction in integrated PET/MR hybrid imaging[J].Ejnm Phys,2015,2(1):1-14.
[6]Lasnon C,Dugue AE,Briand M,et al.NEMA NU 4-optimized reconstructions for therapy assessment in cancer research with the inveon small animal PET/CT system[J].Mol Imaging Biol,2015,17(3):403-412.
[7]Wang GC,Li X,Niu X,et al.PET timing performance measurement method using NEMA NEC phantom[J].IEEETrans Nucl Sci,2016,63(3):1335-1342.
[8]Demir M,Toklu T,Abuqbeitah M,et al.Evaluation of PETscanner performance in PET/MR and PET/CT systems:NEMAtests[J].Mol Imaging Radion Ther,2018,27(1):10-18.
[9]Manco L,Tonini E,Barboni A,et al.Quality assurance for PET/CT system:NEMA NU2-2012 protocol on the new Siemens biograph mCT flow[J].Phys Med,2016,32(1):108.
[10]Pajak MZ,Volgyes D,Pimlott SL,et al.NEMA NU4-2008performance evaluation of albira:A two-ring small-animal PETsystem using continuous LYSO crystals[J].Open Med J,2016,3(1):12-26.
[11]Aghanejad A,Jalilian AR,Ardaneh K,et al.Preparation and quality control of 68Ga-citrate for PET applications[J].Asia Ocean J Nucl Med Biol,2015,3(2):99-106.
[12]姚之丰,章英剑,王新村,等.按照NEMA NU2-2007标准测试Biograph mCT-S64 PET性能[J].肿瘤影像学,2014,23(3):205-210.
[13]刘辉,宋颖.PET设备系统性能测试及分析[J].中国辐射卫生,2016,25(6):696-699.
[14]胡红波,胡莹,丘志芬,等.一种用于PET/CT呼吸运动伪影校正性能测试的动态体模设计[J].中国医疗设备,2017,32(1):30-33.
[15]吕志征,贺强,王洪伟,等.某医院核医学科PET/CT中心放射防护分析[J].中国辐射卫生,2016,25(1):76-78.
[16]Sato K,Shidahara M,Watabe H,et al.Performance evaluation of the small-animal PET scanner ClairvivoPET using NEMA NU4-2008 Standards[J].Phys Med Biol,2016,61(2):696-711.
[17]Belcari N,Camarlinghi N,Ferretti S,et al.NEMA NU-4performance evaluation of the IRIS PET/CT preclinical scanner[J].IEEE Trans Rad Plas Med Sci,2017,1(4):301-309.