药物球囊与普通球囊治疗下肢动脉硬化闭塞症的临床效果评价
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摘要
目的比较药物球囊与普通球囊治疗下肢动脉硬化闭塞症的临床效果。方法比较我院接诊的下肢动脉硬化闭塞症患者中17例接受药物球囊治疗(观察组)与15例接受普通球囊治疗(对照组)患者的预后情况。结果两组患者手术成功率及术后1个月总有效率比较,差异无统计学意义(P>0.05);观察组患者ABI、6MWT均显著高于对照组,差异有统计学意义(P<0.05);观察组患者靶动脉通畅率显著高于对照组,继发血栓形成率和靶动脉再狭窄率均显著低于对照组,差异有统计学意义(P<0.05)。结论药物球囊能够提高下肢动脉硬化闭塞症远期预后效果,降低再狭窄率,值得临床推荐。
Objective To compare the clinical effects of drug balloon and common balloon in treating arteriosclerosis obliterans of lower limbs. Methods The prognosis of 17 patients with arteriosclerosis obliterans admitted to our hospital who were treated with drug balloon(observation group) and 15 patients treated with conventional balloon(control group) were compared. Results There was no significant difference between the two groups in the success rate of operation and the total effective rate at 1 months after operation(P > 0.05).The ABI and 6 MWT in the observation group were significantly higher than those in the control group(P < 0.05).The rate of target artery patency in the observation group was significantly higher than that in the control group.The secondary thrombus formation rate and the target artery restenosis rate were significantly lower than those in the control group,the difference was statistically significant(P < 0.05). Conclusion The drug balloon can improve the long-term prognosis of arteriosclerosis obliterans of lower limbs and reduce the restenosis rate,which is worthy of clinical recommendation.
Objective To compare the clinical effects of drug balloon and common balloon in treating arteriosclerosis obliterans of lower limbs. Methods The prognosis of 17 patients with arteriosclerosis obliterans admitted to our hospital who were treated with drug balloon(observation group) and 15 patients treated with conventional balloon(control group) were compared. Results There was no significant difference between the two groups in the success rate of operation and the total effective rate at 1 months after operation(P > 0.05).The ABI and 6 MWT in the observation group were significantly higher than those in the control group(P < 0.05).The rate of target artery patency in the observation group was significantly higher than that in the control group.The secondary thrombus formation rate and the target artery restenosis rate were significantly lower than those in the control group,the difference was statistically significant(P < 0.05). Conclusion The drug balloon can improve the long-term prognosis of arteriosclerosis obliterans of lower limbs and reduce the restenosis rate,which is worthy of clinical recommendation.
引文
[1]朱晓亮,曹烨民.下肢动脉硬化闭塞症的治疗研究[J].中国医药科学,2015,5(23):46-48,65.
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[6]吴中俭,谷涌泉,齐立行,等.单纯球囊扩张与联合药物涂层支架置入治疗膝下动脉闭塞性疾病的效果比较[J].中国医药导报,2017,14(22):66-68.
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[9]史作磊,王坤,于振海.下肢动脉硬化闭塞症手术或介入治疗后血管再狭窄的影响因子[J].中国血管外科杂志(电子版),2014,6(3):183-185.
[10]项以力,杨镛.球囊扩张治疗下肢动脉硬化闭塞症的研究进展[J].中国血管外科杂志(电子版),2015,7(4):306-309.
[11]白斗,蒋岚杉,武少辉,等.球囊扩张术与经皮腔内支架成形术治疗下肢动脉硬化闭塞的效果对比分析[J].西南军医,2017,19(6):511-515.
[12]尹智明,余朝文.下肢动脉硬化闭塞症腔内介入治疗的研究进展[J].中国普通外科杂志,2017,26(6):789-794.
[13]孙利坤,王兵,吴斐,等.药物涂层球囊治疗股腘动脉硬化闭塞症的临床研究[J].中国普通外科杂志,2017,26(6):806-811.
[14]林福森,朴龙,李星云,等.介入治疗87例下肢动脉硬化闭塞症的疗效分析[J].延边大学医学学报,2017,40(1):52-54.
[15]刘波,段月琴.内膜下血管成形术治疗下肢动脉硬化闭塞病人的临床评价[J].内蒙古医科大学学报,2017,39(1):79-81.
[2]张天华,迟德财,姜维良.药物涂层球囊治疗下肢动脉硬化闭塞症的疗效[J].中国普通外科杂志,2016,25(12):1719-1724.
[3]赵纪春,杨轶.下肢动脉硬化闭塞症腔内治疗[J].中国实用外科杂志,2016,36(12):1263-1268.
[4]包俊敏.下肢动脉闭塞腔内治疗策略的新思考[J].中国血管外科杂志(电子版),2017,9(2):81-83.
[5]尹智明,余朝文.下肢动脉硬化闭塞症腔内介入治疗的研究进展[J].中国普通外科杂志,2017,26(6):789-794.
[6]吴中俭,谷涌泉,齐立行,等.单纯球囊扩张与联合药物涂层支架置入治疗膝下动脉闭塞性疾病的效果比较[J].中国医药导报,2017,14(22):66-68.
[7]杜自忠,李健.下肢动脉硬化闭塞症介入治疗近远期疗效评估[J].内科,2015,10(5):643-645.
[8]庄金满,李选,李天润,等.股腘动脉病变球囊扩张与支架植入的疗效对比研究[J].北京大学学报(医学版),2016,48(1):160-165.
[9]史作磊,王坤,于振海.下肢动脉硬化闭塞症手术或介入治疗后血管再狭窄的影响因子[J].中国血管外科杂志(电子版),2014,6(3):183-185.
[10]项以力,杨镛.球囊扩张治疗下肢动脉硬化闭塞症的研究进展[J].中国血管外科杂志(电子版),2015,7(4):306-309.
[11]白斗,蒋岚杉,武少辉,等.球囊扩张术与经皮腔内支架成形术治疗下肢动脉硬化闭塞的效果对比分析[J].西南军医,2017,19(6):511-515.
[12]尹智明,余朝文.下肢动脉硬化闭塞症腔内介入治疗的研究进展[J].中国普通外科杂志,2017,26(6):789-794.
[13]孙利坤,王兵,吴斐,等.药物涂层球囊治疗股腘动脉硬化闭塞症的临床研究[J].中国普通外科杂志,2017,26(6):806-811.
[14]林福森,朴龙,李星云,等.介入治疗87例下肢动脉硬化闭塞症的疗效分析[J].延边大学医学学报,2017,40(1):52-54.
[15]刘波,段月琴.内膜下血管成形术治疗下肢动脉硬化闭塞病人的临床评价[J].内蒙古医科大学学报,2017,39(1):79-81.