腹腔镜胆囊切除术治疗胆结石的临床效果
|
摘要
目的观察腹腔镜胆囊切除术治疗胆结石的临床效果。方法选取本院2017年1月至2018年1月收治的90例胆结石患者为研究对象,按入院时间单双号将其分为对照组(45例,小切口胆囊切除术)与治疗组(45例,腹腔镜胆囊切除术)。比较两组的治疗效果。结果治疗组手术时长、切口长度、术中出血量、下床活动时间、肛门排气时间、住院时间均优于对照组(P<0.05)。治疗后,两组C反应蛋白、血清白介素-6、肿瘤坏死因子水平均升高,但治疗组明显低于对照组(P<0.05)。治疗后,两组IgA、IgG、IgM水平均降低,但治疗组明显高于对照组(P<0.05)。治疗后,两组超氧化物歧化酶、还原型谷胱甘肽过氧化物酶水平均降低,丙二醛水平均升高(P<0.05);治疗组超氧化物歧化酶、还原型谷胱甘肽过氧化物酶水平高于对照组,丙二醛水平低于对照组(P<0.05)。结论腹腔镜胆囊切除术在胆结石治疗中应用效果显著,其可促进患者康复,减轻患者的炎症反应与应激反应,提高其免疫力,值得临床推广。
Objective To observe the clinical effect of laparoscopic cholecystectomy in the treatment of gallstones.Methods A total of 90 patients with gallstones admitted in our hospital from January 2017 to January 2018 were selected as study objects, and divided into control group(45 cases, minilaparotomy cholecystectomy) and treatment group(45 cases,laparoscopic cholecystectomy) according to the odd and even number of the admission time. The treatment effects of the two groups were compared. Results The operation time, incision length, intraoperative bleeding volume, time of getting out of bed and anal exhaust and hospital stay in the treatment group were better than those in the control group(P<0.05). After treatment, the levels of C-reaction protein, interleukin-6 and tumor necrosis factor of two groups increased, but those in the treatment group were significantly lower than the control group(P<0.05). After treatment, the levels of IgA, IgG and IgM of two groups decreased, but those in the treatment group were higher than the control group(P<0.05). After treatment,the levels of superoxide dismutase and reductive glutathione peroxidase of two groups decreased, while the levels of malondialdehyde increased(P <0.05); the levels of superoxide dismutase and reductive glutathione peroxidase in the treatment group were higher than those in the control group, while the level of malondialdehyde in the treatment group was lower than that in the control group(P<0.05). Conclusion Laparoscopic cholecystectomy has a remarkable effect in the treatment of gallstones, it can promote rehabilitation of patients, alleviate the inflaminatory reaction and stress reaction and improve immunity of patients, which is worthy of clinical promotion.
Objective To observe the clinical effect of laparoscopic cholecystectomy in the treatment of gallstones.Methods A total of 90 patients with gallstones admitted in our hospital from January 2017 to January 2018 were selected as study objects, and divided into control group(45 cases, minilaparotomy cholecystectomy) and treatment group(45 cases,laparoscopic cholecystectomy) according to the odd and even number of the admission time. The treatment effects of the two groups were compared. Results The operation time, incision length, intraoperative bleeding volume, time of getting out of bed and anal exhaust and hospital stay in the treatment group were better than those in the control group(P<0.05). After treatment, the levels of C-reaction protein, interleukin-6 and tumor necrosis factor of two groups increased, but those in the treatment group were significantly lower than the control group(P<0.05). After treatment, the levels of IgA, IgG and IgM of two groups decreased, but those in the treatment group were higher than the control group(P<0.05). After treatment,the levels of superoxide dismutase and reductive glutathione peroxidase of two groups decreased, while the levels of malondialdehyde increased(P <0.05); the levels of superoxide dismutase and reductive glutathione peroxidase in the treatment group were higher than those in the control group, while the level of malondialdehyde in the treatment group was lower than that in the control group(P<0.05). Conclusion Laparoscopic cholecystectomy has a remarkable effect in the treatment of gallstones, it can promote rehabilitation of patients, alleviate the inflaminatory reaction and stress reaction and improve immunity of patients, which is worthy of clinical promotion.
引文
[1]王安江,张令宇,张真真,等.腹腔镜胆囊切除术与开腹手术治疗胆结石的临床效果观察[J].当代医学,2018,24(23):61-63.
[2]念宽余.腹腔镜胆囊切除术对胆结石的治疗效果[J].临床医学研究与实践,2018,3(19):54-55.
[3]李玉贵.浅谈小切口胆囊切除术治疗胆囊结石的临床效果[J].智慧健康,2018,4(17):46-47.
[4]石启奎.小切口胆囊切除术与腹腔镜胆囊切除术治疗胆囊结石的临床对比[J].临床医药文献电子杂志,2018,5(45):18,20.
[5]李兆然.腹腔镜胆囊切除术与小切口胆囊切除术治疗胆结石临床疗效对比分析[J].影像研究与医学应用,2018,2(12):228-230.
[6]张二辉.腹腔镜与小切口胆囊切除术治疗胆结石的效果比较[J].河南医学研究,2018,27(8):1456-1457.
[7] JATEGAONKAR PA,YADAV SP.MESH/MESHLESS paraumbilical hernia repair with concomitant single-incision transumbilical threeport laparoscopic cholecystectomy-prospective observational study of126 patients[J].J Laparoendosc Adv Surg Tech A,2014,24(2):60-65.
[8]郭彩峰.腹腔镜与小切口手术切除胆囊治疗胆囊结石的疗效对比分析[J].医药论坛杂志,2018,39(4):54-56.
[9]顾坚.小切口、腹腔镜胆囊切除术对胆结石的治疗效果比较[J].临床医药文献电子杂志,2018,5(39):44.
[10]寇吉平.腹腔镜胆囊切除术与小切口胆囊切除术治疗胆结石临床疗效对比评价[J].中国医疗器械信息,2018,24(8):30-31.
[2]念宽余.腹腔镜胆囊切除术对胆结石的治疗效果[J].临床医学研究与实践,2018,3(19):54-55.
[3]李玉贵.浅谈小切口胆囊切除术治疗胆囊结石的临床效果[J].智慧健康,2018,4(17):46-47.
[4]石启奎.小切口胆囊切除术与腹腔镜胆囊切除术治疗胆囊结石的临床对比[J].临床医药文献电子杂志,2018,5(45):18,20.
[5]李兆然.腹腔镜胆囊切除术与小切口胆囊切除术治疗胆结石临床疗效对比分析[J].影像研究与医学应用,2018,2(12):228-230.
[6]张二辉.腹腔镜与小切口胆囊切除术治疗胆结石的效果比较[J].河南医学研究,2018,27(8):1456-1457.
[7] JATEGAONKAR PA,YADAV SP.MESH/MESHLESS paraumbilical hernia repair with concomitant single-incision transumbilical threeport laparoscopic cholecystectomy-prospective observational study of126 patients[J].J Laparoendosc Adv Surg Tech A,2014,24(2):60-65.
[8]郭彩峰.腹腔镜与小切口手术切除胆囊治疗胆囊结石的疗效对比分析[J].医药论坛杂志,2018,39(4):54-56.
[9]顾坚.小切口、腹腔镜胆囊切除术对胆结石的治疗效果比较[J].临床医药文献电子杂志,2018,5(39):44.
[10]寇吉平.腹腔镜胆囊切除术与小切口胆囊切除术治疗胆结石临床疗效对比评价[J].中国医疗器械信息,2018,24(8):30-31.