支气管镜介入治疗气道良恶性肿瘤患者60例临床效果分析
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摘要
目的探讨支气管镜介入治疗气道肿瘤的临床效果。方法选取2012年1月至2018年6月我院收治的60例气道肿瘤患者作为研究对象,其中良性肿瘤患者26例,恶性肿瘤患者34例。对患者进行支气管镜介入治疗,比较良性肿瘤患者和恶性肿瘤患者治疗前后的第一秒用力呼气容积(FEV1)、用力肺活量(FVC)、气道狭窄段腔径和气促指数,计算恶性肿瘤患者术后1年生存率。结果术后,26例气道良性肿瘤患者气道内肿瘤组织全部切除,患者呼吸困难、胸闷、气促等症状消失;术后1个月,患者的FEV1、FVC、气道狭窄段腔径、气促指数评分均优于治疗前,差异有统计学意义(P<0.05)。气道恶性肿瘤患者术后显效30例,有效3例,无效1例;术后1个月,患者的FEV1、FVC、气道狭窄段腔径、气促指数评分均优于治疗前,差异有统计学意义(P<0.05);术后1年生存率为47.06%(16/34)。结论支气管镜介入治疗气道肿瘤患者临床效果显著,能够有效缓解症状,改善通气状况。
Objective To investigate the clinical effect of bronchoscopy on respiratory tumor. Methods A total of 60 patients with respiratory tumor admitted to our hospital from January 2012 to June 2018 were selected as subjects, including 26 patients with benign tumor and 34 patients with malignant tumor. Patients were treated with bronchoscopic interventional therapy. the forced expiratory volume in 1 second(FEV1), the forced vital capacity(FVC), respiratory tract stenosis segment diameter and shortness of breath index before and after treatment were compared on patients with benign tumor and malignant tumor, and the one-year survival rate on patients with malignant tumor was calculated. Results All the tumor tissues were removed on 26 patients with benign respiratory tumor, and the patient′s dyspnea, chest tightness, shortness of breath and other symptoms were disappeared after operation. One month after operation, the patients′ FEV1, FVC, respiratory tract stenosis segment diameter and shortness of breath index were all better than those before treatment, and the difference was statistically significant(P<0.05). On patients with respiratory malignant tumor, 30 cases were markedly effective, 3 cases were effective, and 1 case was ineffective. One month after operation, the patients′ FEV1, FVC, respiratory tract stenosis segment diameter and shortness of breath index were all better than those before treatment, and the difference was statistically significant(P<0.05). The one-year survival rate was 47.06%(16/34). Conclusion The clinical effect of bronchoscopy on patients with respiratory tumor is significant, which can effectively relieve symptoms and improve ventilation condition.
Objective To investigate the clinical effect of bronchoscopy on respiratory tumor. Methods A total of 60 patients with respiratory tumor admitted to our hospital from January 2012 to June 2018 were selected as subjects, including 26 patients with benign tumor and 34 patients with malignant tumor. Patients were treated with bronchoscopic interventional therapy. the forced expiratory volume in 1 second(FEV1), the forced vital capacity(FVC), respiratory tract stenosis segment diameter and shortness of breath index before and after treatment were compared on patients with benign tumor and malignant tumor, and the one-year survival rate on patients with malignant tumor was calculated. Results All the tumor tissues were removed on 26 patients with benign respiratory tumor, and the patient′s dyspnea, chest tightness, shortness of breath and other symptoms were disappeared after operation. One month after operation, the patients′ FEV1, FVC, respiratory tract stenosis segment diameter and shortness of breath index were all better than those before treatment, and the difference was statistically significant(P<0.05). On patients with respiratory malignant tumor, 30 cases were markedly effective, 3 cases were effective, and 1 case was ineffective. One month after operation, the patients′ FEV1, FVC, respiratory tract stenosis segment diameter and shortness of breath index were all better than those before treatment, and the difference was statistically significant(P<0.05). The one-year survival rate was 47.06%(16/34). Conclusion The clinical effect of bronchoscopy on patients with respiratory tumor is significant, which can effectively relieve symptoms and improve ventilation condition.
引文
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[2] 张华平,曾奕明,陈晓阳,等.经纤维支气管镜射频治疗在恶性中央气道狭窄中的应用[J].第三军医大学学报,2014,36(20):2148-2149.
[3] 陈晔,张泽明,冯欣,等.经支气管镜介入治疗支气管内型错构瘤2例[J].河北医药,2015,37(13):2078-2079.
[4] 陈国峰,黄海燕.支气管镜下高频电刀治疗气道平滑肌瘤的临床应用[J].中国内镜杂志,2015,21(4):404-406.
[5] 封萌,杨增荣,焦克岗,等.支气管镜介入治疗联合局部应用紫杉醇治疗良性气道瘢痕狭窄的临床研究[J].中国内镜杂志,2016,22(1):19-23.
[6] 李勤,何元兵,夏宇,等.经支气管镜介入治疗大气道狭窄40例疗效分析[J].中国内镜杂志,2015,21(8):884-886.
[7] 燕真锋,司少魁,王小娟.中心气道少见肿瘤16例支气管镜介入治疗体会[J].西北国防医学杂志,2015,36(11):760-761.
[8] 丁银锋,陈龙,黄海东,等.支气管镜介入治疗原发性气管肿瘤的临床分析[J].中华结核和呼吸杂志,2017,40(6):435-439.