早期综合管理对妊娠期贫血患者干预效果评价
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摘要
目的探讨妊娠期贫血患者进行早期综合管理干预的效果。方法选取256例早期妊娠期贫血患者,将其随机分为对照组和观察组,每组128例;对照组给予常规管理和治疗,而观察组则给予早期综合管理干预措施;比较两组患者治疗后的血红蛋白、血清铁蛋白、总有效率、不良妊娠结局发生率等指标。结果治疗前,两组的血红蛋白、血清铁蛋白水平比较差异无统计学意义(t1=0. 524,t2=0. 376,P>0. 05);治疗后,观察组的血红蛋白、血清铁蛋白水平均高于对照组(t1=9. 732,t2=3. 574,P <0. 01);观察组的总有效率为95. 31%,高于对照组的81. 25%(χ~2=12. 234,P <0. 01);观察组的不良妊娠结局总发生率为9. 38%,低于对照组的34. 38%(χ~2=24. 578,P <0. 01)。结论妊娠期贫血患者进行早期综合管理干预后,可提高血红蛋白和血清铁蛋白水平,改善贫血状况,降低母婴不良妊娠结局发生率。
Objective To explore the intervention effect of anemia patients during pregnancy through the intervention of early integrated management. Methods A total of 256 cases of anemia patients during pregnancy were randomly assigned into control group and observation group,128 cases in each group. The control group was offered conventional management and treatment,and the observation group adopted intervention measures of early integrated management. The indexes of hemoglobin,serum ferritin,total effective rate and incidence rate of adverse pregnancy outcome were compared between the two groups after treatment. Results Before treatment,there were no statistically significant differences in hemoglobin and serum ferritin between the two groups( t1= 0. 524,t2= 0. 376,P > 0. 05). After treatment,the levels of hemoglobin and serum ferritin in the observation group were both higher than the control group( t1= 9. 732,t2= 3. 574,P < 0. 01). The total effective rate of the observation group was 95. 31%,higher than the control group( 81. 25%,χ~2= 12. 234,P < 0. 01). The total incidence rate of adverse pregnancy outcome of the observation group was 9. 38%,lower than the control group( 34. 38%,χ~2=24. 578,P < 0. 01). Conclusions After the intervention of early integrated management,the patients of anemia during pregnancy have raised levels of hemoglobin and serum ferritin,improved anemia status,and decreased incidence rate of adverse pregnancy outcome.
Objective To explore the intervention effect of anemia patients during pregnancy through the intervention of early integrated management. Methods A total of 256 cases of anemia patients during pregnancy were randomly assigned into control group and observation group,128 cases in each group. The control group was offered conventional management and treatment,and the observation group adopted intervention measures of early integrated management. The indexes of hemoglobin,serum ferritin,total effective rate and incidence rate of adverse pregnancy outcome were compared between the two groups after treatment. Results Before treatment,there were no statistically significant differences in hemoglobin and serum ferritin between the two groups( t1= 0. 524,t2= 0. 376,P > 0. 05). After treatment,the levels of hemoglobin and serum ferritin in the observation group were both higher than the control group( t1= 9. 732,t2= 3. 574,P < 0. 01). The total effective rate of the observation group was 95. 31%,higher than the control group( 81. 25%,χ~2= 12. 234,P < 0. 01). The total incidence rate of adverse pregnancy outcome of the observation group was 9. 38%,lower than the control group( 34. 38%,χ~2=24. 578,P < 0. 01). Conclusions After the intervention of early integrated management,the patients of anemia during pregnancy have raised levels of hemoglobin and serum ferritin,improved anemia status,and decreased incidence rate of adverse pregnancy outcome.
引文
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[7]曹宇,李悦,杨虹,等.针对性治疗与经验疗法对妊娠贫血产妇预后及分娩结局的影响[J].中国药物经济学,2018,13(1):59-62.
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[10]何晓琳,谭秀燕.多糖铁联合维生素A、B2、叶酸治疗妊娠贫血的疗效及对新生儿结局的影响[J].国际医药卫生导报,2017,23(24):3894-3897.
[2]俞春芝,赵现立,康瑛.妊娠期贫血发病的高危因素及对妊娠结局的影响[J].中国妇幼保健,2017,32(23):5827-5830.
[3]曹泽毅.中华妇产科学[M].第3版.北京:人民卫生出版社,2014:1472-1494.
[4]唐宇平,应豪.妊娠期贫血及其规范管理[J].中国实用妇科与产科杂志,2014,30(6):431-434.
[5]杨六计,余海丽.琥珀酸亚铁叶酸片对孕晚期贫血孕妇妊娠不良结局的影响[J].河北医药,2013,35(18):2756-2757.
[6]郭碧辉,吴立明,杨桂春.琥珀酸亚铁叶酸片对孕晚期贫血孕妇临床效果及妊娠不良结局的影响[J].北方药学,2016,13(8):184-185.
[7]曹宇,李悦,杨虹,等.针对性治疗与经验疗法对妊娠贫血产妇预后及分娩结局的影响[J].中国药物经济学,2018,13(1):59-62.
[8]王艳丽.妊娠期贫血对妊娠结局的影响分析[J].按摩与康复医学,2015,6(12):40.
[9]张竑卉.妊娠期缺铁性贫血干预时机与妊娠结局的关系[J].齐齐哈尔医学院学报,2014,35(3):358-359.
[10]何晓琳,谭秀燕.多糖铁联合维生素A、B2、叶酸治疗妊娠贫血的疗效及对新生儿结局的影响[J].国际医药卫生导报,2017,23(24):3894-3897.