陕西省铜川市HIV/AIDS生存时间及影响因素
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摘要
目的了解铜川市HIV/AIDS生存状况及影响生存的因素。方法采用回顾性队列研究,收集2003—2017年铜川市266例HIV/AIDS一般人口学特征、艾滋病感染和生存相关信息,利用寿命表分析累计生存率,Cox回归模型分析生存影响因素。结果 266例HIV/AIDS最短观察期0个月,最长147个月,平均27.6个月,中位数21(QR:7～41)个月;随访218例,失访5例,艾滋病相关死亡40例,其他3例。1年、4年和7年以上艾滋病累计生存率分别为88.0%、79.0%和73.5%;经单因素和多因素Cox分析显示抗病毒治疗能够有效降低HIV/AIDS死亡的风险(OR=19.202,95%CI9.394～39.314)。结论铜川市应加强艾滋病防治宣传工作,针对青少年、服务业人群及农民开展健康教育,树立正确的性安全观,支持社会组织开展艾滋病防控工作,及时开展HIV/AIDS的CD4细胞检测,为抗病毒治疗效果评价提供依据,加强艾滋病抗病毒治疗,有效提高HIV/AIDS的生活质量。
Objective To understand the living condition of HIV/AIDS and its influencing factors in Tongchuan City.Methods A retrospective cohort study was conducted to collect the general demographic characteristics, HIV infection and survival-related information of 266 cases of HIV/AIDS in Tongchuan City from 2003 to 2017. The cumulative survival rate was analyzed by life table and the influencing factors of survival were analyzed by Cox regression Model. Results The shortest observation period of 266 HIV/AIDS was 0 month, the longest was 147 months. The average was 27.6 months, median 21(QR:7-41) months; 218 cases were followed up, 5 cases were lost, 40 cases were dead because of AIDS-related and 3 cases were others. The cumulative survival rate of 1 year, 4 years and more than 7 years was 88.0%, 79.0% and 73.5% respectively.Univariate and multivariate Cox analysis showed that antiviral therapy could effectively reduce the risk of HIV/AIDS death(OR=19.202,95%CI 9.394-39.314). Conclusion We should strengthen the propaganda work of AIDS prevention and control in Tongchuan. Aiming at the young people and the service groups, farmers should carry out health education, establish a correct concept of sexual safety, support social organizations to carry out AIDS prevention and control work, and carry out the CD4 cell detection of HIV/AIDS in time, so as to provide the basis for the evaluation of the effect of antiviral therapy. Strengthen AIDS anti-viral treatment, effectively improve the quality of life of HIV/AIDS. Treatment can effectively improve the quality of life of HIV/AIDS.
Objective To understand the living condition of HIV/AIDS and its influencing factors in Tongchuan City.Methods A retrospective cohort study was conducted to collect the general demographic characteristics, HIV infection and survival-related information of 266 cases of HIV/AIDS in Tongchuan City from 2003 to 2017. The cumulative survival rate was analyzed by life table and the influencing factors of survival were analyzed by Cox regression Model. Results The shortest observation period of 266 HIV/AIDS was 0 month, the longest was 147 months. The average was 27.6 months, median 21(QR:7-41) months; 218 cases were followed up, 5 cases were lost, 40 cases were dead because of AIDS-related and 3 cases were others. The cumulative survival rate of 1 year, 4 years and more than 7 years was 88.0%, 79.0% and 73.5% respectively.Univariate and multivariate Cox analysis showed that antiviral therapy could effectively reduce the risk of HIV/AIDS death(OR=19.202,95%CI 9.394-39.314). Conclusion We should strengthen the propaganda work of AIDS prevention and control in Tongchuan. Aiming at the young people and the service groups, farmers should carry out health education, establish a correct concept of sexual safety, support social organizations to carry out AIDS prevention and control work, and carry out the CD4 cell detection of HIV/AIDS in time, so as to provide the basis for the evaluation of the effect of antiviral therapy. Strengthen AIDS anti-viral treatment, effectively improve the quality of life of HIV/AIDS. Treatment can effectively improve the quality of life of HIV/AIDS.
引文
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[5]李虹璇,何海,栾荣生,等.2006-2015年成都市成华区男男性行为人群艾滋病疫情分析[J].寄生虫病与感染性疾病,2017,15(1):21-25.
[6]李幼丽,李月宜,刘静,等.郴州市2007-2015年艾滋病疫情分析[J].实用预防医学,2017,24(5):617-619.
[7]王保山,赵琳,胡玉宏,等.2003-2016年德州市德城区艾滋病疫情分析[J].预防医学论坛,2017,23(9):680-682.
[8]熊馥,解瑞青,柯贤洲,等.黄石市2011-2017年艾滋病疫情及流行特征分析[J].中国热带医学,2018,18(9):906-909.
[9]姚书杰,潘珊,周金玲,等.辽宁省艾滋病抗病毒治疗效果评价[J].中国公共卫生,2013,29(9):1376-1377.
[10]陈洪森,温金平,黄晓明,等.1999-2011年岑溪市艾滋病感染者及病人生存分析[J].实用预防医学,2013,20(6):681-683.
[11]李斯斯,农全兴,徐永芳,等.广西南宁1999-2014年艾滋病感染者/患者生存状况分析[J].中国公共卫生,2015,31(12):1569-1573.
[12]金玫华,杨中荣,董正全,等.湖州市艾滋病抗病毒治疗效果分析[J].预防医学,2016,28(10):1019-1020.
[13]赵艳秋,赵秀萍,傅卓华,等.苏州市艾滋病抗病毒治疗效果分析[J].江苏预防医学,2015,26(2):7-9.
[14]张静,冯艳洁,刘毅,等.秦皇岛市2013-2015年新报告HIV/AIDS病例首次CD4~+T淋巴细胞检测结果[J].中国热带医学,2018,18(4):399-401.2018-11-21
[2]刘登来,甘松辉,吴文杰,等.1997-2016年舟山市艾滋病患者生存时间及影响因素分析[J].南昌大学学报(医学版),2018,58(3):56-61.
[3]中国疾病预防控制中心性病艾滋病预防控制中心.国家免费艾滋病抗病毒药物治疗手册[M].4版.北京:人民卫生出版社,2016.
[4]吴尊友.中国艾滋病防治面临新形势与新挑战[J].中国公共卫生,2011,27(12):1505-1507.
[5]李虹璇,何海,栾荣生,等.2006-2015年成都市成华区男男性行为人群艾滋病疫情分析[J].寄生虫病与感染性疾病,2017,15(1):21-25.
[6]李幼丽,李月宜,刘静,等.郴州市2007-2015年艾滋病疫情分析[J].实用预防医学,2017,24(5):617-619.
[7]王保山,赵琳,胡玉宏,等.2003-2016年德州市德城区艾滋病疫情分析[J].预防医学论坛,2017,23(9):680-682.
[8]熊馥,解瑞青,柯贤洲,等.黄石市2011-2017年艾滋病疫情及流行特征分析[J].中国热带医学,2018,18(9):906-909.
[9]姚书杰,潘珊,周金玲,等.辽宁省艾滋病抗病毒治疗效果评价[J].中国公共卫生,2013,29(9):1376-1377.
[10]陈洪森,温金平,黄晓明,等.1999-2011年岑溪市艾滋病感染者及病人生存分析[J].实用预防医学,2013,20(6):681-683.
[11]李斯斯,农全兴,徐永芳,等.广西南宁1999-2014年艾滋病感染者/患者生存状况分析[J].中国公共卫生,2015,31(12):1569-1573.
[12]金玫华,杨中荣,董正全,等.湖州市艾滋病抗病毒治疗效果分析[J].预防医学,2016,28(10):1019-1020.
[13]赵艳秋,赵秀萍,傅卓华,等.苏州市艾滋病抗病毒治疗效果分析[J].江苏预防医学,2015,26(2):7-9.
[14]张静,冯艳洁,刘毅,等.秦皇岛市2013-2015年新报告HIV/AIDS病例首次CD4~+T淋巴细胞检测结果[J].中国热带医学,2018,18(4):399-401.2018-11-21