中药足浴联合西药治疗气郁体质失眠临床研究
|
摘要
目的:观察中药足浴联合西药治疗气郁体质失眠的临床疗效。方法:选取气郁体质失眠患者126例,随机分成治疗组和对照组,各63例。对照组采用西药艾司唑仑片治疗,治疗组在对照组基础上给予中药足浴,比较2组治疗前后匹茨堡睡眠质量指数量表评分(PSQI)、临床疗效及气郁体质得分情况。结果:治疗前,2组睡眠质量、进入睡眠时间、睡眠时间、睡眠效率、睡眠障碍、催眠药物、日间功能及总分、气郁体质积分比较,差异均无统计学意义(P> 0.05)。治疗后,2组睡眠质量、进入睡眠时间、睡眠时间、睡眠效率、睡眠障碍、催眠药物、日间功能及总分较治疗前显著降低,差异均有统计学意义(P <0.05);治疗组气郁体质积分较治疗前显著降低(P <0.05);治疗组睡眠质量、催眠药物评分及总分、气郁体质积分显著低于对照组(P <0.05)。治疗组总有效率为95.08%,对照组总有效率为83.05%,2组比较,差异有统计学意义(P <0.05)。治疗组的不良反应率为3.28%,对照组的不良反应率为13.56%,2组比较,差异有统计学意义(P <0.05)。结论:中药足浴联合西药治疗气郁体质失眠疗效显著,中药熏洗治疗气郁体质失眠的优势在于改善睡眠质量及减少催眠药物使用。
Objective: To observe the clinical effect of Chinese medicine foot bath combined with western medicine for insomnia with qi depression constitution. Methods: Selected 126 cases of patients with insomnia with qi depression constitution and divided them into the treatment group and the control group randomly,63 cases in each group. The control group was given western medicine estazolam tablets,while the treatment group was additionally given Chinese medicine foot bath. Compared the scores of Pittsburgh sleep quality index(PSQI),clinical effect and qi depression constitution before and after treatment. Results: Before treatment, there were no significant differences being found in the comparisons of sleep quality, sleep time, time of falling asleep, sleep efficiency, sleep disorders, hypnotics, daytime function and its total score,and qi depression scores between the two groups(P > 0.05). After treatment,the sleep quality,sleep time,time of falling asleep, sleep efficiency, sleep disorders, hypnotics, daytime function and its total score in the two groups were significantly lower than those before treatment,differences being significant(P < 0.05);the score of qi depression constitution in the treatment group was obviously decreased when compared with that before treatment(P < 0.05);and the sleep quality,hypnotics score,the total score and qi depression score in the treatment group were clearly lower than those in the control group(P < 0.05). The total effective rate was 95.08% in the treatment group and 83.05% in the control group, difference being significant(P < 0.05). The adverse reaction rate was 3.28% in the treatment group and 13.56% in the control group,difference being significant(P < 0.05). Conclusion:The application of Chinese medicine foot bath combined with western medicine has significant effect in treating insomnia with qi depression constitution. The advantage of Chinese medicine fumigation and washing in treating insomnia with qi depression constitution is to improve the sleep quality and reduce the use of hypnotics.
Objective: To observe the clinical effect of Chinese medicine foot bath combined with western medicine for insomnia with qi depression constitution. Methods: Selected 126 cases of patients with insomnia with qi depression constitution and divided them into the treatment group and the control group randomly,63 cases in each group. The control group was given western medicine estazolam tablets,while the treatment group was additionally given Chinese medicine foot bath. Compared the scores of Pittsburgh sleep quality index(PSQI),clinical effect and qi depression constitution before and after treatment. Results: Before treatment, there were no significant differences being found in the comparisons of sleep quality, sleep time, time of falling asleep, sleep efficiency, sleep disorders, hypnotics, daytime function and its total score,and qi depression scores between the two groups(P > 0.05). After treatment,the sleep quality,sleep time,time of falling asleep, sleep efficiency, sleep disorders, hypnotics, daytime function and its total score in the two groups were significantly lower than those before treatment,differences being significant(P < 0.05);the score of qi depression constitution in the treatment group was obviously decreased when compared with that before treatment(P < 0.05);and the sleep quality,hypnotics score,the total score and qi depression score in the treatment group were clearly lower than those in the control group(P < 0.05). The total effective rate was 95.08% in the treatment group and 83.05% in the control group, difference being significant(P < 0.05). The adverse reaction rate was 3.28% in the treatment group and 13.56% in the control group,difference being significant(P < 0.05). Conclusion:The application of Chinese medicine foot bath combined with western medicine has significant effect in treating insomnia with qi depression constitution. The advantage of Chinese medicine fumigation and washing in treating insomnia with qi depression constitution is to improve the sleep quality and reduce the use of hypnotics.
引文
[1]Doghramji K.The epidemiology and diagnosis of insomnia[J].Am J Manag Care,2006,12(8 Suppl):214-220.
[2]李倩,傅小燕,曲丽芳.63例失眠患者与抑郁的相关性研究[J].中华中医药学刊,2013,31(1):141-143.
[3]李强.失眠病因病机及临床辨证论治分析[J].光明中医,2015,30(12):2655-2656.
[4]中华医学会精神病学分会.中国精神障碍分类与诊断标准第三版(CCMD-3)[J].中华精神科杂志,2001,34(3):184-188.
[5]中华中医药学会.中医体质分类与判定(ZYYXH/T157-2009)[J].世界中西医结合杂志,2009,4(4):303-304.
[6]王琦,朱燕,薛禾生,等.中医体质量表的初步编制[J].中国临床康复,2006,10(3):12-14.
[7]郑筱萸.中药新药临床研究指导原则(试行)[M].北京:中国医药科技出版社,2002:223-383.
[8]陈锹发,李秋艳,马学竹.李秋艳治疗失眠临床经验[J].世界中西医结合杂志,2017,12(1):37-39,77.
[9]付聪,陈云飞.慢性失眠---矛盾性失眠的临床及机制研究[J].生理科学进展,2015,25(4):295-298.
[10]张瀚元,刘兴山.失眠的中西医治疗[J].长春中医药大学学报,2015,31(5):966-967.
[11]陈俊玲.失眠症中医药诊治最新进展[J].世界中医药,2016,11(B06):1986-1987.
[12]唐楚英,郭静,王麟鹏,等.原发性失眠的中西医治疗概述[J].世界中西医结合杂志,2015,10(6):869-873.
[13]王琦,朱燕波.中国一般人群中医体质流行病学调查:基于全国9省市21948例流行病学调查数据[J].中华中医药杂志,2009,24(1):7-12.
[14]章莹,王飞,史话跃,等.气郁质与中医肝系亚健康状态关系的探讨[J].中华中医药杂志,2015,30(3):679-681.
[15]黄清苑,温利辉,徐金燕,等.柴胡加龙骨牡蛎汤治疗气郁质失眠症30例临床观察[J].北方药学,2016,13(5):87-88.
[16]张莺,沈叶静,胡炜,等.角调音乐疗法结合柴胡加龙骨牡蛎汤加减治疗气郁质失眠48例临床观察[J].中医杂志,2017,58(18):1577-1580.
[17]刘明月,侯献兵,周永梅,等.气郁体质体病相关的临床研究概况[J].中医药导报,2015,21(22):86-87.
[2]李倩,傅小燕,曲丽芳.63例失眠患者与抑郁的相关性研究[J].中华中医药学刊,2013,31(1):141-143.
[3]李强.失眠病因病机及临床辨证论治分析[J].光明中医,2015,30(12):2655-2656.
[4]中华医学会精神病学分会.中国精神障碍分类与诊断标准第三版(CCMD-3)[J].中华精神科杂志,2001,34(3):184-188.
[5]中华中医药学会.中医体质分类与判定(ZYYXH/T157-2009)[J].世界中西医结合杂志,2009,4(4):303-304.
[6]王琦,朱燕,薛禾生,等.中医体质量表的初步编制[J].中国临床康复,2006,10(3):12-14.
[7]郑筱萸.中药新药临床研究指导原则(试行)[M].北京:中国医药科技出版社,2002:223-383.
[8]陈锹发,李秋艳,马学竹.李秋艳治疗失眠临床经验[J].世界中西医结合杂志,2017,12(1):37-39,77.
[9]付聪,陈云飞.慢性失眠---矛盾性失眠的临床及机制研究[J].生理科学进展,2015,25(4):295-298.
[10]张瀚元,刘兴山.失眠的中西医治疗[J].长春中医药大学学报,2015,31(5):966-967.
[11]陈俊玲.失眠症中医药诊治最新进展[J].世界中医药,2016,11(B06):1986-1987.
[12]唐楚英,郭静,王麟鹏,等.原发性失眠的中西医治疗概述[J].世界中西医结合杂志,2015,10(6):869-873.
[13]王琦,朱燕波.中国一般人群中医体质流行病学调查:基于全国9省市21948例流行病学调查数据[J].中华中医药杂志,2009,24(1):7-12.
[14]章莹,王飞,史话跃,等.气郁质与中医肝系亚健康状态关系的探讨[J].中华中医药杂志,2015,30(3):679-681.
[15]黄清苑,温利辉,徐金燕,等.柴胡加龙骨牡蛎汤治疗气郁质失眠症30例临床观察[J].北方药学,2016,13(5):87-88.
[16]张莺,沈叶静,胡炜,等.角调音乐疗法结合柴胡加龙骨牡蛎汤加减治疗气郁质失眠48例临床观察[J].中医杂志,2017,58(18):1577-1580.
[17]刘明月,侯献兵,周永梅,等.气郁体质体病相关的临床研究概况[J].中医药导报,2015,21(22):86-87.