一种氰乙酸乙酯合成的新方法
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摘要
以氰乙酸、无水乙醇为原料,采用酸性树脂催化合成氰乙酸乙酯。分析和讨论了反应温度,氰乙酸与无水乙醇的摩尔比,精馏前粗品质量和精馏操作条件对氰乙酸乙酯的纯度和收率的影响,在该条件下,氰乙酸乙酯的产品纯度可以达到99.5%以上,收率在93.0%以上。
With cyanoacetic acid and anhydrous ethanol as raw material,ethyl cyanoacetate was synthesized by catalysis of acid resin catalyst.The influences of reaction condition,including reaction temperature,the molar ratio of cyanoacetic acid and anhydrous ethanol,crude product's quality before rectification and operating condition of rectification on product quality and yield was analyzed.In this condition.product purity of ethyl cyanoacetate can reach more than 99.5%,the yield over 93.0%.
With cyanoacetic acid and anhydrous ethanol as raw material,ethyl cyanoacetate was synthesized by catalysis of acid resin catalyst.The influences of reaction condition,including reaction temperature,the molar ratio of cyanoacetic acid and anhydrous ethanol,crude product's quality before rectification and operating condition of rectification on product quality and yield was analyzed.In this condition.product purity of ethyl cyanoacetate can reach more than 99.5%,the yield over 93.0%.
引文
[1]杨英,李德臣.α-氰基丙烯酸酯生产新工艺[J].中国胶黏剂,2003,13(5):46-47.
[2]陈晓曼,庞春安.用固体酸催化和相转移进行氰乙酸乙酯的合成[J].陕西化工,1994(4):18-21.
[3]邱滔,李桂勇,吕新宇.类水滑石催化氰乙酸甲酯与乙醇的酯交换反应[J].石油化工,2008,37(3):272-276.
[4]尚会建,康丽娜,赵叶,等.杂多酸催化合成氰乙酸乙酯的研究[J].精细石油化工,2012.5,29(3):48-51.
[5]杨德明,郭新连.连续精馏分离氰乙酸甲酯工艺[J].化工进展,2008,27(3):
[2]陈晓曼,庞春安.用固体酸催化和相转移进行氰乙酸乙酯的合成[J].陕西化工,1994(4):18-21.
[3]邱滔,李桂勇,吕新宇.类水滑石催化氰乙酸甲酯与乙醇的酯交换反应[J].石油化工,2008,37(3):272-276.
[4]尚会建,康丽娜,赵叶,等.杂多酸催化合成氰乙酸乙酯的研究[J].精细石油化工,2012.5,29(3):48-51.
[5]杨德明,郭新连.连续精馏分离氰乙酸甲酯工艺[J].化工进展,2008,27(3):