无创通气联合信必可对慢性阻塞性肺疾病合并慢性呼吸衰竭的疗效评价
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摘要
目的分析无创通气联合信必可治疗慢性阻塞性肺疾病(COPD)合并慢性呼吸衰竭的临床效果。方法将120例COPD合并慢性呼吸衰竭患者随机分为两组,各60例。对照组接受无创通气治疗,观察组接受无创通气联合信必可治疗。比较两组治疗后动脉血气指标、肺功能参数和临床疗效的差异。结果治疗后,两组患者的动脉血气指标和肺功能水平均有显著改善(P <0. 01),且观察组的Pa CO_2、PaO_2、FEV_1和FEV_1/FVC变化幅度均大于对照组(P <0. 01);观察组治疗效果优于对照组(P <0. 01)。结论应用无创通气联合信必可疗法,可有效改善COPD合并慢性呼吸衰竭的肺通气功能,降低Pa CO_2升高PaO_2,缓解临床症状。
Objective To discuss the clinical significance of combined application of noninvasive ventilation and the Xin Bi Ke for treatment of chronic obstructive pulmonary disease( COPD) with chronic respiratory failure. Methods Randomly divided 120 cases of COPD with chronic respiratory failure into observation group and control group,60 patients in each group. The control one received non-invasive ventilation treatment and the observation one received noninvasive ventilation plus the Xin Bi Ke. Comparison of arterial blood gas component,pulmonary ventilation function and clinical curative effect was finished between the two groups. Results After treatment,Pa CO_2,PaO_2,FEV_1 and FEV_1/FVC changed significantly in both groups. However,the changes in the above parameters in the observation group displayed higher magnitude compared with the control group( P < 0. 01). The total efficiency of the observation group appeared better than that of the control group( P < 0. 01). Conclusion The treating scheme in this paper improved pulmonary ventilation function,reduced Pa CO_2,raised PaO_2 and alleviated clinical manifestations in the COPD patients with chronic respiratory failure.
Objective To discuss the clinical significance of combined application of noninvasive ventilation and the Xin Bi Ke for treatment of chronic obstructive pulmonary disease( COPD) with chronic respiratory failure. Methods Randomly divided 120 cases of COPD with chronic respiratory failure into observation group and control group,60 patients in each group. The control one received non-invasive ventilation treatment and the observation one received noninvasive ventilation plus the Xin Bi Ke. Comparison of arterial blood gas component,pulmonary ventilation function and clinical curative effect was finished between the two groups. Results After treatment,Pa CO_2,PaO_2,FEV_1 and FEV_1/FVC changed significantly in both groups. However,the changes in the above parameters in the observation group displayed higher magnitude compared with the control group( P < 0. 01). The total efficiency of the observation group appeared better than that of the control group( P < 0. 01). Conclusion The treating scheme in this paper improved pulmonary ventilation function,reduced Pa CO_2,raised PaO_2 and alleviated clinical manifestations in the COPD patients with chronic respiratory failure.
引文
[1]周春霞,江山平.慢性阻塞性肺疾病合并心血管疾病的研究进展[J].中华结核和呼吸杂志,2015,38(1):72-75.
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[5]赵静,刘瑞娟.肺功能检查在慢性阻塞性肺疾病诊治中的临床价值评估[J].中国医药指南,2013,11(26):333-334.
[6]李佳倩,章璐,陈芳,等.慢性阻塞性肺疾病患者生活质量评估研究近况[J].现代医药卫生,2012,28(16):2481-2482.
[7]王银娟.慢性阻塞性肺疾病合并呼吸衰竭患者应用无创通气联合信必可治疗的效果[J].大家健康(学术版),2015,9(22):101-102.
[8]王晓雯.信必可联合无创通气治疗老年慢性阻塞性肺疾病呼吸衰竭患者的疗效观察[J].黑龙江医药,2014,27(4):924-926.
[2]丁晓英,李雯.舒利迭联合无创通气治疗老年慢性阻塞性肺疾病呼吸衰竭的疗效[J].实用医学杂志,2009,25(11):2823-2825.
[3]汪利华,何玉萍.无创通气联合福莫特罗布地奈德粉吸入剂治疗重度COPD合并慢性呼吸衰竭效果观察[J].海峡药学,2015,27(7):117-119.
[4]王会娟,王昌明.慢性阻塞性肺疾病与全身炎症反应相关性的研究进展[J].国际呼吸杂志,2011,31(7):531-535.
[5]赵静,刘瑞娟.肺功能检查在慢性阻塞性肺疾病诊治中的临床价值评估[J].中国医药指南,2013,11(26):333-334.
[6]李佳倩,章璐,陈芳,等.慢性阻塞性肺疾病患者生活质量评估研究近况[J].现代医药卫生,2012,28(16):2481-2482.
[7]王银娟.慢性阻塞性肺疾病合并呼吸衰竭患者应用无创通气联合信必可治疗的效果[J].大家健康(学术版),2015,9(22):101-102.
[8]王晓雯.信必可联合无创通气治疗老年慢性阻塞性肺疾病呼吸衰竭患者的疗效观察[J].黑龙江医药,2014,27(4):924-926.