脂蛋白a与新疆维、汉族冠心病患者及冠脉病变支数的相关性研究
|
摘要
目的:调查脂蛋白a与冠心病、冠状动脉病变支数的相关性。方法:选取2017年12月～2018年3月行冠脉造影确诊冠心病的292例患者,分成维吾尔族88例,汉族204例,分析两组患者脂蛋白a及冠脉病变的特点。结果:维吾尔族冠心病患者的危险因素多、冠脉病变复杂,且脂蛋白a是维吾尔族冠心病的独立危险因素。结论:脂蛋白a与冠脉病变支数的严重程度呈正相关,可以作为维吾尔族冠心病患者更强的预测因子。
Objective:To investigate the changes of the lipoprotein(a) and coronary artery disease and to investigate the correlations of Lp( a)with coronary artery disease severity. Methods: A total of 292 patients were divided two groups with coronary heart disease were enrolled from December 2017 to March 2018, of which 88 Uyghur and 204 Han,analysis serum lipoprotein(a) level and severity of coronary artery stenosis. Results: Uygur patients have many risk factors and complicated coronary lesions,Lp(a) was the independent risk factors in Uygur patients. Conclusion: lipoprotein(a) are associated with the severity of coronary artery disease,the indicators of Lp(a) should be more detected in Uygur patients.
Objective:To investigate the changes of the lipoprotein(a) and coronary artery disease and to investigate the correlations of Lp( a)with coronary artery disease severity. Methods: A total of 292 patients were divided two groups with coronary heart disease were enrolled from December 2017 to March 2018, of which 88 Uyghur and 204 Han,analysis serum lipoprotein(a) level and severity of coronary artery stenosis. Results: Uygur patients have many risk factors and complicated coronary lesions,Lp(a) was the independent risk factors in Uygur patients. Conclusion: lipoprotein(a) are associated with the severity of coronary artery disease,the indicators of Lp(a) should be more detected in Uygur patients.
引文
[1] Laschkolnig A,Kollerits B,Lamina C,et al.Lipoprotein (a) concentrations,apolipoprotein (a) phenotypes,and peripheral arterial disease in three independent cohorts[J].Cardiovascular Research,2014,103(1):28-36.
[2] 罗仁,茶春喜,梁金排.不同年龄组维吾尔族与汉族冠心病患者的危险因素与冠状动脉病变特征分析[J].重庆医学,2014,43(04):445-447.
[3] 钱琦,姜海,郭守玉,等.血清脂蛋白(a)与冠心病的关系[J].中国循证心血管医学杂志,2016,8(10):1201-1203.
[4] Kamstrup P R,Tybj?rg-Hansen A,Nordestgaard B G.Extreme Lipoprotein(a) Levels and Improved Cardiovascular Risk Prediction[J].Journal of the American College of Cardiology,2013,61(11):1146-1156.
[5] 寇世杰,王凯,李静.血浆脂蛋白(a)水平与冠心病及冠脉病变程度的关系[J].赤峰学院学报(自然科学版),2016,32(05):20-21.
[6] Mitsuda T,Uemura Y,Ishii H,et al.Lipoprotein(a) levels predict adverse vascular events after acute myocardial infarction[J].Heart & Vessels,2016,31(12):1-7.
[7] 黄文军,刘俊明,谢伟,等.汉族、维吾尔族、哈萨克族冠心病患者冠状动脉病变的临床研究[J].中国介入心脏病学杂志,2012,20(04):212-216.
[8] 姚娟,李国庆,雷建新,等.维吾尔族和汉族冠心病危险因素与冠状动脉病变对照分析[J].心血管康复医学杂志,2008(01):24-27.
[9] 杨天伦,方叶青,李传昶,等.冠心病危险因素聚集与冠脉病变的相关分析[J].中国现代医学杂志,2003(17):68-70.
[10] 左瑞平,张建军,韩常宝.脂蛋白(α)的生理功能及其与冠心病的研究进展[J].心脏杂志,2016,28(02):244-247.
[2] 罗仁,茶春喜,梁金排.不同年龄组维吾尔族与汉族冠心病患者的危险因素与冠状动脉病变特征分析[J].重庆医学,2014,43(04):445-447.
[3] 钱琦,姜海,郭守玉,等.血清脂蛋白(a)与冠心病的关系[J].中国循证心血管医学杂志,2016,8(10):1201-1203.
[4] Kamstrup P R,Tybj?rg-Hansen A,Nordestgaard B G.Extreme Lipoprotein(a) Levels and Improved Cardiovascular Risk Prediction[J].Journal of the American College of Cardiology,2013,61(11):1146-1156.
[5] 寇世杰,王凯,李静.血浆脂蛋白(a)水平与冠心病及冠脉病变程度的关系[J].赤峰学院学报(自然科学版),2016,32(05):20-21.
[6] Mitsuda T,Uemura Y,Ishii H,et al.Lipoprotein(a) levels predict adverse vascular events after acute myocardial infarction[J].Heart & Vessels,2016,31(12):1-7.
[7] 黄文军,刘俊明,谢伟,等.汉族、维吾尔族、哈萨克族冠心病患者冠状动脉病变的临床研究[J].中国介入心脏病学杂志,2012,20(04):212-216.
[8] 姚娟,李国庆,雷建新,等.维吾尔族和汉族冠心病危险因素与冠状动脉病变对照分析[J].心血管康复医学杂志,2008(01):24-27.
[9] 杨天伦,方叶青,李传昶,等.冠心病危险因素聚集与冠脉病变的相关分析[J].中国现代医学杂志,2003(17):68-70.
[10] 左瑞平,张建军,韩常宝.脂蛋白(α)的生理功能及其与冠心病的研究进展[J].心脏杂志,2016,28(02):244-247.