摘要
生物活性肽是一类源于生物且具有不同生物活性的产物。一般由几个到几十个氨基酸组成,氨基酸排列顺序各异、结构多样。这些肽生物活性多样,包括抗菌、抗病毒、抗肿瘤、抗氧化、心血管保护作用(抗高血压、抗动脉粥样化和抗凝血)、免疫调节、镇痛、抗焦虑、抗糖尿病、抑制食欲和神经活性等作用,一些生物活性肽具有一定的营养价值和药用价值,因此也吸引了保健品和制药行业对活性肽的关注。一些生物活性肽或其衍生物具有很高的商业价值,部分已经进入制药行业或营养食品的市场。其中的大部分如今已处于不同的临床试验阶段或临床前试验阶段。本文主要介绍了生物活性肽调节免疫功能目前的研究状况以及对未来发展前景进行展望,并着重介绍这些生物活性肽的营养价值。
the biologically active peptide is a kind of biological product with different biological activity. Dozens of amino acids in peptides vary from sequence to structure. Their bioactivities include anti-bacterium,anti-virus,anti-tumor,anti-oxidation,cardiovascular protection( anti-hypertension,anti-atheroma and anti-coagulant),immune regulation,analgesia,antianxiety,anti-diabetes,and suppressing appetite and neural activity. Some bioactive peptides contribute to the nutritional and medicinal value,so they attract the attention of the dietary supplements and pharmaceutical industry. Because of the high values in commerce of some bioactive peptides or its derivatives,some have been adopted in the pharmaceutical industry or nutrition food markets. Most of them are in different stages of clinical trials or in preclinical trials now. This paper mainly introduces the current research status and the development prospects about the regulating immune function of bioactive peptides,and emphatically introduces the nutritional value of them.
引文
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