三仁润肠方治疗功能性便秘60例
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摘要
目的:评价三仁润肠方治疗功能性便秘的临床疗效。方法:将60例功能性便秘的患者分成治疗组、对照组各30例,治疗组用三仁润肠方治疗,每日早晚餐前100 m L,疗程4周;对照组用乳果糖口服液治疗,每次15 m L,每日2次,疗程4周。两组均于初诊首日、第2周、第4周、停药后1个月进行便秘的中医证候评分,比较两组之间中医证候积分,并计算有效率。结果:治疗4周后治疗组有效率(90%)较对照组有效率(46. 43%)有明显的优势(P <0. 05),停药1个月后治疗组有效率(76. 67%)仍高于对照组(21. 43%)。结论:三仁润肠方可以显著增加FC患者的排便次数、改善大便性状以及缓解腹胀,且复发率较低。
Objective: To observe and evaluate the clinical efficacy of functional constipation. Methods: Sixty patients with functional constipation were divided into the treatment group and the control group,30 cases in each. The treatment group was treated with Sanren Runchang Formula and took 100 m L before every morning and evening meals. The course of treatment was 4 weeks.The other group took lactulose,twice a day for 4 weeks at a time of 15 m L. TCM syndrome scores of constipation in two groups on first day of first medical treatment and at second and fourth week and 1 month after stopping the drug,comparing of TCM syndrome scores between the two groups and computing the efficiency. Results: The efficiency in treatment group( 90%) was more than the control group's( 46. 43%) after 4 weeks( P < 0. 05) and the treatment group's( 76. 67%) was higher than the control group's( 21. 43%) 1 month after stopping drugs. Conclusion: Sanren Runchang Formula can significantly increase the times of defecation,improve the character of stool and relieve abdominal distention and the treatment had a lower recurrence rate.
Objective: To observe and evaluate the clinical efficacy of functional constipation. Methods: Sixty patients with functional constipation were divided into the treatment group and the control group,30 cases in each. The treatment group was treated with Sanren Runchang Formula and took 100 m L before every morning and evening meals. The course of treatment was 4 weeks.The other group took lactulose,twice a day for 4 weeks at a time of 15 m L. TCM syndrome scores of constipation in two groups on first day of first medical treatment and at second and fourth week and 1 month after stopping the drug,comparing of TCM syndrome scores between the two groups and computing the efficiency. Results: The efficiency in treatment group( 90%) was more than the control group's( 46. 43%) after 4 weeks( P < 0. 05) and the treatment group's( 76. 67%) was higher than the control group's( 21. 43%) 1 month after stopping drugs. Conclusion: Sanren Runchang Formula can significantly increase the times of defecation,improve the character of stool and relieve abdominal distention and the treatment had a lower recurrence rate.
引文
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[11]Rao SS,Seaton K,Miller MJ,et al.Psychological profiles and quality of life differ between patients with dyssynergia and those with slow transit constipation[J].J Psychosomat Res,2007,63(4):441-449.
[12]Chan AO,Cheng C,Hui WM,et al.Differing coping mechanisms,stress level and anorectal physiology in patients with functional constipation[J].World J of Gastroenterol,2005,11(34):5362.
[13]顾珈裔,于冰娥,常玉娟,等.三仁润肠方治疗慢传输型功能性便秘临床研究[J].中国中西医结合消化杂志,2013,21(8):403-406.
[2]王晓艾.中医辨证治疗小儿功能性便秘研究进展[J].实用中医药杂志,2016,6,32(6):635-637.
[3]李军祥.芪黄通秘软胶囊治疗功能性便秘的临床研究[J].中成药,2016,38(8):1703-1707.
[4]杨春玲,马晓丽.临床治愈186例小儿功能性便秘的证候方药体会及远期疗效分析[J].中医临床研究,2017,9(21):101-104.
[5]杨洋,程遥,史海霞,等.功能性便秘合并焦虑抑郁状态中医诊疗思路[J].辽宁中医杂志,2017,44(3):492-493.
[6]翁剑锋,邱啸臣,李元新.功能性便秘的治疗进展[J].中国临床研究,2016,29(3):409-412.
[7]Zhou H,Yao M,Cheng GY,et al.Prevalence and associated factors of functional gastrointestinal disorders and bowel habits in Chinese adolescents:a school-based study[J].Pediatr Gastroenterol Nutr,2011,53(2):168-173.
[8]Shariati A,Maceda JS,Hale DS.High-fiber diet for treatment of constipation in women with pelvic floor disorders[J].Obstetrics Gynecol,2008,111(4):908-913.
[9]López RJ,Martínez GAB,Luque A,et al.The effect of a fibre enriched dietary milk product in chronic primary idiopatic constipation[J].Nutricion Hospitalaria,2008,23(1):12-19.
[10]Mugie SM,Benninga MA,Di LC.Epidemiology of constipation in children and adults:a systematic review[J].Best Practice&Research Clinical Gastroenterology,2011,25(1):3-18.
[11]Rao SS,Seaton K,Miller MJ,et al.Psychological profiles and quality of life differ between patients with dyssynergia and those with slow transit constipation[J].J Psychosomat Res,2007,63(4):441-449.
[12]Chan AO,Cheng C,Hui WM,et al.Differing coping mechanisms,stress level and anorectal physiology in patients with functional constipation[J].World J of Gastroenterol,2005,11(34):5362.
[13]顾珈裔,于冰娥,常玉娟,等.三仁润肠方治疗慢传输型功能性便秘临床研究[J].中国中西医结合消化杂志,2013,21(8):403-406.