活血灵在髋臼骨折围手术期的应用
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摘要
目的:总结活血灵在髋臼骨折围手术期的应用效果。方法:75例髋臼骨折患者按时间分为观察组38例和对照组37例,对照组在围手术期间给以常规处理,观察组在对照组基础上结合活血灵口服,观察两组术后2周血液流变学指标,统计深静脉血栓发生情况。结果:观察组在术后14 d血液流变学指标与对照组比较,差异有统计学意义(P<0.05)。同时,观察组术后14 d时D-二聚体为(2.57±0.51)mg/L,较术前(4.26±1.72)mg/L比较,差异有统计学意义(P<0.05),且观察组术后14 d时D-二聚体、下肢深静脉血栓较对照组减少(P<0.05)。结论:髋臼骨折围手术期应用活血灵,能有效改善术后血液流变学和D-二聚体指标,减少下肢深静脉血栓的发生。
Objective To observe the therapeutic effects of Huoxueling decoction on patients in periopera-tive period of acetabulum fracture.MethodsSeventy-five acetabulum fracture patients were randomly divid-ed into the observation group(38 patients) and the control group(37 patients); the control group attended symptom-atic treatment during perioperative period,while the observation group had Huoxueling decoction, then the wounddrainage, hemorheology indexes,D-dimmer, and lower extremity deep venous thrombosis of both groups were ob-served.ResultsCompared with the preoperative conditions,the hemorheology indexes of observation group onthe 14 d postoperative was lower(P < 0.05). Meanwhile,the D-dimmer of observation group was declined from(4.26±1.72)mg/L preoperatively to(2.57±0.51)mg/L on 14 d postoperatively,the difference was statisticallysignificant(P < 0.05). In addition,the D-dimmer,lower extremity deep venous thrombosis of observation groupon the 14 d was lower than that of control group(P < 0.05).ConclusionThe application of Huoxueling de-coction on patients in perioperative period of acetabulum fracture can effectively improve hemorheology indexesand D-dimmer,and can not increase wound drainage, thus worthy of clinical application.
Objective To observe the therapeutic effects of Huoxueling decoction on patients in periopera-tive period of acetabulum fracture.MethodsSeventy-five acetabulum fracture patients were randomly divid-ed into the observation group(38 patients) and the control group(37 patients); the control group attended symptom-atic treatment during perioperative period,while the observation group had Huoxueling decoction, then the wounddrainage, hemorheology indexes,D-dimmer, and lower extremity deep venous thrombosis of both groups were ob-served.ResultsCompared with the preoperative conditions,the hemorheology indexes of observation group onthe 14 d postoperative was lower(P < 0.05). Meanwhile,the D-dimmer of observation group was declined from(4.26±1.72)mg/L preoperatively to(2.57±0.51)mg/L on 14 d postoperatively,the difference was statisticallysignificant(P < 0.05). In addition,the D-dimmer,lower extremity deep venous thrombosis of observation groupon the 14 d was lower than that of control group(P < 0.05).ConclusionThe application of Huoxueling de-coction on patients in perioperative period of acetabulum fracture can effectively improve hemorheology indexesand D-dimmer,and can not increase wound drainage, thus worthy of clinical application.
引文
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[13]张舜欣,李俊来,刘萃,等.年龄校正的D-二聚体在老年深静脉血栓诊断中的价值[J].中华心血管病杂志,2013,41(11):945-949.
[14]胡勇斌,傅强,俞能宝,等.老年髋部骨折围手术期中医药治疗进展[J].中国药师,2013,16(4):616-618.
[15]张晓强,高菲菲,王战朝,等.膝伤活血灵口服配合低分子肝素钙皮下注射对全膝关节置换术后隐性失血的影响[J].中医正骨,2014,26(4):23-25.
[2]陈康,黄振飞,崔巍,等.高位髂腹股沟入路治疗累及四方区髋臼骨折[J].中华骨科杂志,2014,34(7):723-729.
[3]周钢,陈鸿奋,王富民,等.髋臼骨折术后并发症的荟萃分析[J].中华创伤骨科杂志,2013,15(8):653-659.
[4]唐天华,唐三元,杨辉.髋臼骨折手术入路与并发症关系的研究进展[J].中华创伤骨科杂志,2014,16(2):169-172.
[5]王武超,刘超,成传德,等.扩大的髋臼后壁骨折的治疗策略[J].中医正骨,2013,25(6):42-43,46.
[6]汤金城,刘超,郭跃生.微型钉在髋臼后壁粉碎性骨折中的应用[J].中国美容医学,2011,20(4):318.
[7]王爱国,谷福顺,郑昆仑,等.老年髋部骨折224例临床分析[J].中国中西医结合外科杂志,2014,20(4):377-379.
[8]谭旭仪,刘又文,高书图,等.益气活血通络汤在全髋关节置换围手术期中的应用研究[J].中国中医骨伤科杂志,2014,22(5):12-14.
[9]韦溦,杨星华,官正华,等.血液流变学及血浆D-9二聚体对骨科大手术后发生深静脉血栓的诊断价值[J].中华创伤杂志,2013,29(8):782-784.
[10]谭旭仪,刘又文,高书图,等.股骨头坏死愈胶囊对股骨头坏死患者血液流变学的影响[J].中成药,2014,36(10):2227-2228.
[11]孙瑜,周荣斌.D-二聚体检测在下肢骨折术后并发深静脉血栓诊断中的价值[J].中医正骨,2012,24(4):22-23.
[12]王刚,张英军,矫浩然,等.利伐沙班治疗骨科手术后下肢深静脉血栓形成35例[J].中国中西医结合外科杂志,2014,20(10):72-74.
[13]张舜欣,李俊来,刘萃,等.年龄校正的D-二聚体在老年深静脉血栓诊断中的价值[J].中华心血管病杂志,2013,41(11):945-949.
[14]胡勇斌,傅强,俞能宝,等.老年髋部骨折围手术期中医药治疗进展[J].中国药师,2013,16(4):616-618.
[15]张晓强,高菲菲,王战朝,等.膝伤活血灵口服配合低分子肝素钙皮下注射对全膝关节置换术后隐性失血的影响[J].中医正骨,2014,26(4):23-25.