红外光谱法快速鉴别大黄不同炮制品配方颗粒
|
摘要
目的建立红外光谱法快速鉴别大黄不同炮制品配方颗粒的方法。方法采用红外光谱结合二阶导数光谱及二维相关光谱法分析不同炮制品配方颗粒光谱特征。结果二阶导数光谱在1200～1800/cm范围内差异较大,二维相关光谱图差异明显。结论通过比较不同炮制品红外光谱图、二阶导数光谱图及二维相关光谱图,可以准确、快速鉴别大黄不同炮制品配方颗粒。
OBJECTIVE To establish a rapid FTIR method for identifying of different processed products of Rhubarb Formula Granules.METHODS Different processed products of Rhubarb Formula Granules were researched by infrared、second derivative spectra and two-dimensional correlation spectroscopy.RESULTS In second derivative spectra,the intensity,shape and position of the peaks were different in the range of 1200～1800/cm,Two-dimensional correlation spectroscopy were obvious difference.CONCLUSION By comparing the infrared spectra、second derivative spectra and two-dimensional correlation spectroscopy of different processed products,It can be identified rapidly and accurately of different processed products of Rhubarb Formula Granules.
OBJECTIVE To establish a rapid FTIR method for identifying of different processed products of Rhubarb Formula Granules.METHODS Different processed products of Rhubarb Formula Granules were researched by infrared、second derivative spectra and two-dimensional correlation spectroscopy.RESULTS In second derivative spectra,the intensity,shape and position of the peaks were different in the range of 1200～1800/cm,Two-dimensional correlation spectroscopy were obvious difference.CONCLUSION By comparing the infrared spectra、second derivative spectra and two-dimensional correlation spectroscopy of different processed products,It can be identified rapidly and accurately of different processed products of Rhubarb Formula Granules.
引文
[1]国家药典委员会编.中国药典(一部)[S].北京:中国医药科技出版社,2015,23-24.
[2]陈亚,江滨,曾元儿.红外光谱在中药鉴别中的应用[J].广州中医药大学学报,2004,21(3):237.
[3]Liu H X,Sun S Q,Lv G H,et al.Study on Angelica and its different extracts by Fourier transform infrared spectroscopy and two-dimensional correlation IR spectroscopy[J].Spectro Acta Part A,2006,64:321.
[4]张特利,李军山,李振江.HPLC法测定儿茶配方颗粒中儿茶素和表儿茶素的含量[J].中国药房,2015,26(15):2114-2116.
[5]甄兰敏,李军山,姜海,等.牛蒡子配方颗粒的质量标准研究[J].中国药房,2015,26(18):2532-2534.
[6]吴镝,赵忠慧.中药配方颗粒的应用与研究[J].中国医药导报,2011,8(25):10.
[7]毕晓黎,彭丽诗,罗文汇.补骨脂与盐补骨脂配方颗粒的红外光谱鉴别[J].中成药,2014,36(10):2152-2155.
[8]曹岗,丛晓东,蔡皓,等.红外光谱与聚类分析法快速鉴别白术生品与炮制品[J].中国新药杂志,2012,21(12):1427-1430.
[9]高晗,李军山,郝鹏彬,等.近红外光谱法快速测定侧柏叶配方颗粒槲皮苷含量[J].中国现代中药,2015,17(7):722-725.
[10]徐海星,陈慧,许沛虎,等.不同产地苍耳子红外指纹图谱鉴别[J].中药材,2014,37(6):971-973.
[11]郭桂明,马莉,穆阳,等.红外光谱技术用于炙制大黄饮片辅料加入与否的快速测定[J].中国实验方剂学杂志,2010,16(13):25-27.
[12]陈影,刘慧,李普玲,等.黄芩不同炮制饮片的红外光谱特征分析[J].中国实验方剂学杂志,2015,21(22):77-81.
[13]周清,温金莲,肖树雄,等.黄芪的红外指纹图谱鉴别研究[J].中国实验方剂学杂志,2011,17(10):79-82.
[14]吴明侠,王晶娟,张贵君,等.野菊花药材不同炮制品的红外鉴别研究[J].时珍国医国药,2011,22(1):211-212.
[15]李普玲,陈建红,刘慧,等.栀子不同炒制饮片的红外光谱分析[J].中国实验方剂学杂志,2015,21(22):82-85.
[16]雷雨,图雅,张艳玲,等.野葛与粉葛的二维红外相关光谱鉴别[J].分析仪器,2010,3:47-49.
[17]毕晓黎,谭志灿,李素梅,等.大黄与酒大黄配方颗粒红外光谱研究[J].中国实验方剂学杂志,2013,19(12):86-88.
[18]毕晓黎,彭丽诗,罗文汇.补骨脂与盐补骨脂配方颗粒的红外光谱鉴别[J].中成药,2014,36(10):2152-2155.
[2]陈亚,江滨,曾元儿.红外光谱在中药鉴别中的应用[J].广州中医药大学学报,2004,21(3):237.
[3]Liu H X,Sun S Q,Lv G H,et al.Study on Angelica and its different extracts by Fourier transform infrared spectroscopy and two-dimensional correlation IR spectroscopy[J].Spectro Acta Part A,2006,64:321.
[4]张特利,李军山,李振江.HPLC法测定儿茶配方颗粒中儿茶素和表儿茶素的含量[J].中国药房,2015,26(15):2114-2116.
[5]甄兰敏,李军山,姜海,等.牛蒡子配方颗粒的质量标准研究[J].中国药房,2015,26(18):2532-2534.
[6]吴镝,赵忠慧.中药配方颗粒的应用与研究[J].中国医药导报,2011,8(25):10.
[7]毕晓黎,彭丽诗,罗文汇.补骨脂与盐补骨脂配方颗粒的红外光谱鉴别[J].中成药,2014,36(10):2152-2155.
[8]曹岗,丛晓东,蔡皓,等.红外光谱与聚类分析法快速鉴别白术生品与炮制品[J].中国新药杂志,2012,21(12):1427-1430.
[9]高晗,李军山,郝鹏彬,等.近红外光谱法快速测定侧柏叶配方颗粒槲皮苷含量[J].中国现代中药,2015,17(7):722-725.
[10]徐海星,陈慧,许沛虎,等.不同产地苍耳子红外指纹图谱鉴别[J].中药材,2014,37(6):971-973.
[11]郭桂明,马莉,穆阳,等.红外光谱技术用于炙制大黄饮片辅料加入与否的快速测定[J].中国实验方剂学杂志,2010,16(13):25-27.
[12]陈影,刘慧,李普玲,等.黄芩不同炮制饮片的红外光谱特征分析[J].中国实验方剂学杂志,2015,21(22):77-81.
[13]周清,温金莲,肖树雄,等.黄芪的红外指纹图谱鉴别研究[J].中国实验方剂学杂志,2011,17(10):79-82.
[14]吴明侠,王晶娟,张贵君,等.野菊花药材不同炮制品的红外鉴别研究[J].时珍国医国药,2011,22(1):211-212.
[15]李普玲,陈建红,刘慧,等.栀子不同炒制饮片的红外光谱分析[J].中国实验方剂学杂志,2015,21(22):82-85.
[16]雷雨,图雅,张艳玲,等.野葛与粉葛的二维红外相关光谱鉴别[J].分析仪器,2010,3:47-49.
[17]毕晓黎,谭志灿,李素梅,等.大黄与酒大黄配方颗粒红外光谱研究[J].中国实验方剂学杂志,2013,19(12):86-88.
[18]毕晓黎,彭丽诗,罗文汇.补骨脂与盐补骨脂配方颗粒的红外光谱鉴别[J].中成药,2014,36(10):2152-2155.