我国清风藤属药用植物研究概况
详细信息    查看全文 | 推荐本文 |
  • 英文篇名:Research progress on Sabia medicinal plants in China
  • 作者:张雪晴 ; 李曼姝 ; 李玉玲 ; 张学学 ; 卢顺光 ; 温秀凤 ; 胡建忠 ; 邹坤
  • 英文作者:ZHANG Xueqing;LI Manshu;LI Yuling;ZHANG Xuexue;LU Shunguang;WEN Xiufeng;HU Jianzhong;ZOU Kun;Hubei Key Laboratory of Natural Products Research & Development,College of Biotechnology & Pharmacy,China Three Gorges University;Soil and Water Conservation Center,the Ministry of Water Resources;
  • 关键词:清风藤属 ; 小花清风藤 ; 化学成分
  • 英文关键词:Sabia;;Sabia parviflora;;chemical constituent
  • 中文刊名:AJSH
  • 英文刊名:Biotic Resources
  • 机构:三峡大学生物与制药学院天然产物研究与利用湖北省重点实验室;水利部水土保持植物开发管理中心;
  • 出版日期:2019-01-02 15:01
  • 出版单位:生物资源
  • 年:2018
  • 期:v.40;No.164
  • 基金:水利部水土保持植物开发管理中心合作项目(No.2017-zg-kj-4/SDHZ2017015;2018-zg-kj-03);; 国家自然科学基金青年科学基金项目(81803383)
  • 语种:中文;
  • 页:AJSH201806001
  • 页数:14
  • CN:06
  • ISSN:42-1886/Q
  • 分类号:4-17
摘要
清风藤属(Sabia)植物是传统民间中药材,具有抗炎止痛、保肝、抗病毒等多种功效,因此具有重要的开发应用前景。通过查阅相关文献资料,从化学成分、临床药理作用、资源分布、生药鉴定、质量标准和提取工艺6个方面对该属植物的研究现状进行综述,为该属植物的进一步研究与开发提供参考。
        The plants of Sabia genus are traditional Chinese herbal medicines with anti-inflammatory,analgesic,liver-protecting,and anti-viral effects,and thus have important development and application prospects. Through literature review,we summarize the research status of this genus of plants from 6 aspects,including chemical constituent,pharmacological effect and clinical application,resource distribution,biopharmaceutical identification,quality standard and extraction process,which provide a reference for further development and utilization.
引文
[1] Chen Y. Studies on the chemical constituents of Sabia parviflora and the nuclear magnetic resonance fingerprint of the genuine medicinal materials[D]. Guiyang:Guizhou University, 2016.陈艳.小花清风藤化学成分的研究和道地药材核磁共振指纹图谱的研究[D].贵阳:贵州大学, 2016.
    [2] Lin C, Cao P X, Liang G Y. Chemical constituents of Sabia parviflora Wal1. ex Roxb.[J]. Nat Prod Res Dev, 2006, 18(B6):42-44.林材,曹佩雪,梁光义.小花清风藤的化学成分研究[J].天然产物研究与开发, 2006, 18(B6):42-44.
    [3] Chen Y, Huang T, Yuan C M, et al. Chemical constituents of Sabia parviflora[J]. Chin Traditi Herbal Drugs, 2015, 46(5), 3146-3150.陈艳,黄滔,苑春茂,等.小花清风藤化学成分的研究[J].中草药, 2015, 46(5):3146-3150.
    [4] Chen J, Deng Y, Tang T J, et al. Study on the constituents of triterpenoids from Sabia parviflora[J]. Chin Tradit Herbal Drugs, 2004, 35(1):16-17.陈谨,邓赟,唐天君,等.小花清风藤三萜成分的研究[J].中草药, 2004, 35(1):16-17.
    [5] Fan D H, Li Z F, Zhao L J, et al. Chemical constituents from the stems and leaves of Sabia parviflora[J]. J Chin Med Mater, 2018, 41(6):1372-1375.樊东辉,李志峰,赵兰君,等.小花清风藤茎叶的化学成分研究[J].中药材, 2018, 41(6):1372-1375.
    [6] Chen J, Chen B, Tian J, et al. Two new pentacyclic triterpenes from Sabia parviflora[J]. Chin Chem Lett,2002, 13(4):345-348.
    [7] Huang Y, Li Q X, Liu Y, et al. Chemical constituents of Sabia fasciculate[J]. Chin Tradit Herbal Drugs,2014, 45(6):765-769.黄艳,李齐修,刘元,等.簇花清风藤的化学成分研究[J],中草药, 2014, 45(6):765-769.
    [8] Liang G Y, Wu K Y, Xu R S, et al. Chemical constituents of Sabia swinhoei[J], Acta Pharm Sin, 1995, 30(5):367-371.梁光义,武孔云,徐任生,等.尖叶清风藤化学成分的研究[J],药学学报, 1995, 30(5):367-371.
    [9] Liang G Y, Zhou Y, Cao P X, et al. Studies on the chemical constituents of Sabia schumanniana[J], Chin Pharm J, 2005, 40(12):900-902.梁光义,周莹,曹佩雪,等.四川清风藤的化学成分研究[J],中国药学杂志, 2005, 40(12):900-902.
    [10] Yuan X, Wang G L, Gong F J. Studies on triterpenoids constituents iaolated from the roots of Sabia schumanniana[J], Acta Bot Sin, 1994, 36(2):153-158.袁晓,王国亮,龚复俊.四川清风藤根皮中三萜成分的研究[J],植物学报, 1994, 36(2):153-158.
    [11] Deng Y, Li X, Wu F E. Studies on the chemical constituents of Sabia yunnanensis[J], Chin Tradit Herbal Drugs, 2006, 37(2):183-185.邓赟,李翔,吴凤锷.云南清风藤化学成分的研究[J],中草药, 2006, 37(2):183-185.
    [12] Liu B M, Huang Y, Li Q X, et al. Chemical constituents of Sabia discolor Dunn[J], Guangxi Sci, 2014, 21(3):257-259.刘布鸣,黄艳,李齐修,等.瑶药白背清风藤的化学成分研究[J],广西科学, 2014, 21(3):257-259.
    [13] Deng Y, Chen J, Chen B, et al. Study on the alkaloids of Sabia parviflora[J]. Nat Prod Res Dev, 2003, 15(4):322-323.邓赟,陈谨,陈斌,等.小花清风藤生物碱成分的研究[J],天然产物研究与开发, 2003, 15(4):322-323.
    [14] Fan D H, Wang Q, Wang Y W, et al. New compounds inhibiting lipid accumulation from the stems of Sabia parviflora[J], Fitoterapia, 2018, 128:218-223.
    [15] Zhao L J, Wang Y W, Li Z F, et al. Isolation and identification of chemical constituents from Sabia parviflora[J], Chin Tradit Herbal Drugs, 2018, 49(3):544-548.赵兰君,王玉伟,李志峰,等.小花清风藤化学成分的分离与鉴定[J],中草药, 2018, 49(3):544-548.
    [16] Wu K Y, Liang G Y, He Z Y, et al. Isolation and identification of fuseine from Sabia swinhoei Hemsl ex Forb et Hemsl[J], J Guizhou Univ(Natural Sciences):2003,20(1):64-65.武孔云,梁光义,贺祝英,等.尖叶清风滕中5-氧阿朴菲碱的分离鉴定[J],贵州大学学报(自然科学版):2003, 20(1):64-65.
    [17] Zhu R H, Luo Q Y, Zhou Y L. The alkaloid of Sinomenium acutum[J], Acta Chem Sin, 1964, 30(3):265-269.朱任宏,罗琦义,周韵麓.清风藤中的生物碱[J],化学学报, 1964, 30(3):265-269.
    [18] Chen Z Y, Qiu C C, Gao C Y, et al. Study on the trace alkaloids of Sinomenium acutum[J], J Beijing Med Univ, 1991, 23(3):235-237.陈稚研,邱翠嫦,高从元,等.清风藤微量生物碱的研究[J],北京医科大学学报, 1991, 23(3):235-237.
    [19] Kou L Q, Wang X L. Chemical constituents of Sinomenium acutum[J], Chin J Med Chem, 2008, 18(4):294-297.寇立群,王晓玲.清风藤化学成分的研究[J],中国药物化学杂志, 2008, 18(4):294-297.
    [20] Lin J, Hao X J, Liang G Y, et al. Chemical constituents of Sabia parviflora[J]. Chin Tradit Herbal Drugs,1999, 30(5):334-335.林佳,郝小江,梁光义,等.小花清风藤化学成分的研究[J],中草药, 1999, 30(5):334-335.
    [21] Zheng J Y, Huang Y, Lin X, et al. GC-MS analysis of liposoluble components in Sabia fasciculata Lecomte ex L. Chen[J], J Pharm Res, 2015, 34(5):195-198.郑金燕,黄艳,林霄,等.簇花清风藤脂溶性成分的GC-MS分析[J],药学研究, 2015, 34(5):195-198.
    [22] Liu Y R, Qiu X C, Chen H. Hepatoprotective effect of Sabia parviflorawall:an experimental study[J], China Pharm, 2008, 19(30):2341-2342.刘易蓉,邱晓春,陈惠.小花清风藤保肝作用实验研究[J],中国药房, 2008, 19(30):2341-2342.
    [23] Yang Y, Zhang Y P, Liang G Y. Protective effect of Xiaohuaqingfengteng capsule on acute liver injury mice and its acute toxicity test[J], Chin JMAP, 2013, 30(11):1166-1170.杨莹,张永萍,梁光义.小花清风藤胶囊的保肝作用研究及其急毒实验[J],中国现代应用药学, 2013, 30(11):1166-1170.
    [24] Yang L F, Jin J X, Gao W X, et al. Protective effect of Qinggan extract on experimental liver injury model in mice[J], Chin J Exp Tradit Med Form, 2006, 12(6):41-42.杨龙飞,金家兴,高文秀,等.清肝浸膏对小鼠实验性肝损伤模型的保护作用[J],中国实验方剂学杂志,2006, 12(6):41-42.
    [25] Yang L F, Jin J X, Zhao H, et al. Effect of Qinggan extract on liver function and pathological changes in rat model of liver injury induced by D-galactose[J], Chin J Exp Tradit Med Form, 2006, 12(4):40-42.杨龙飞,金家兴,赵晖,等.清肝浸膏对D-氨基半乳糖致肝损伤模型大鼠肝功能及病理改变的影响[J],中国实验方剂学杂志, 2006, 12(4):40-42.
    [26] Zhang S S, Fu S X, Li Y S, et al. Pharmacological action of sabianine A[J], Acta Pharm Sinica, 1960, 8(4):177-180.张士善,傅绍萱,李蕴山,等.清风藤硷甲的药理作用[J],药学学报, 1960, 8(4):177-180.
    [27] Li J F, Wu Z D. Anti-inflammatory effect of the extract from Sinomenium acutum[J], J Chin Med Mater,1999, 22(9):472-473.李瑾翡,吴招娣.清风藤水提物"风湿可克"的消炎作用[J],中药材, 1999, 22(9):472-473.
    [28] Xu C M, Wang W S, Lu C F, et al. Qing Feng Teng:an experimental study of anti-inflammation effect[J],Heilongjiang Med Pharm, 1999, 22(6):7-8.徐春媚,王文生,卢春凤,等.清风藤抗炎作用的实验研究[J],黑龙江医药科学, 1999, 22(6):7-8.
    [29] Pan Z B, Li F C, Liao Y E, et al. Study on anti-inflammatory and analgesic effects of water extract of Qinghuateng[J], Chin J ethnomed ethnopharm, 2012, 21(2):27-29.潘照斌,李棐朝,廖月娥,等.簇花清风藤水提物抗炎镇痛作用研究[J],中国民族民间医药, 2012, 21(2):27-29.
    [30] Pan Z B, Li F C, Liao Y E, et al. Study on anti-inflammatory and analgesic effects of alcohol extract of Qinghuateng[J], Yunnan J Tradit Chin Med Mater Med,2012, 33(1):61-62.潘照斌,李棐朝,廖月娥,等.簇花清风藤醇提物镇痛抗炎作用研究[J],云南中医中药杂志, 2012, 33(1):61-62.
    [31] Qu X Y, Zhang H M, Zhang X J, et al. Anti-influenza A virus activity of the extract from Sabia parviflora Wall in vivo[J], Lett Biotechnol, 2015, 26(6):802曲新艳,张会敏,张晓娟,等,小花清风藤水提物体内抗流感病毒的研究[J],生物技术通讯, 2015, 26(6):802-804.
    [32] Wang M L, Wang Y P, Yang Y Y, et al. Effect of Sabia parviflora on the expression of tumor necrosis factor-αand matrix metalloproteinase-9 in rats with rheumatoid arthritis[J], Hunan J Tradit Chin Med, 2018, 34(3):154-157.王茂林,王永萍,杨奕樱,等.小花清风藤对类风湿关节炎大鼠TNF-α和MMP-9表达的影响[J],湖南中医杂志, 2018, 34(3):154-157.
    [33] Long X J. Research progress of sinomenine[J], Cent South Pharm, 2003, 1(5):299-301.龙湘俊.青藤碱研究进展[J],中南药学, 2003, 1(5):299-301.
    [34] Xu S Y. Application research of ten ethnic medicines in Guizhou[J]. World Sci Technol/moderni tradit Chin Med Mater Med, 2006, 8(6):73-78.徐树芸.贵州十种民族药的应用研究[J].世界科学技术中医药现代化, 2006, 8(6):73-78.
    [35] Hu Z J, Xu S W, Xu Y Z. Clinical summary of 84 cases of viral hepatitis treated with Sabia parviflora[J],Guizhou Med J, 1989, 13(1):48.胡柞俊,徐少文,徐耀中.小花清风藤治疗病毒性肝炎84例临床总结[J],贵州医药, 1989, 13(1):48.
    [36] Li C F, Tong S Q, Huang W. Treatment of 56 Cases of Rheumatoid Arthritis with Sinomenium acutum and Methotrexate[J], Capital Med, 2002, 62.李春芬,佟胜全,黄炜.清风藤联合氨甲喋吟治疗类风湿关节炎56例[J],首都医药, 2002, 62.
    [37] Xiong L Q, Yu S P, Li W L, et al. Survey of clinical application research of Sinomenium acutum[J], Asia Pacific Tradit Med, 2017, 13(5):63-65.熊力群,余舒鹏,李文龙,等.清风藤临床应用研究概况[J],亚太传统医药, 2017, 13(5), 63-65.
    [38] Han Y Z, Pan H Y, Yan J K. Experimental observation on the effect of Sabia limoniacea on uterus[J],Guangxi Med J, 1982, 4(2):59-61.韩延宗,潘汉焰,颜吉魁.柠檬清风藤对子宫作用的实验观察[J],广西医学, 1982, 4(2):59-61.
    [39] Wen D, Sun Q W, Pan G J, et al. Research progress in Sabia medical plants[J], Guizhou Sci, 2016, 34(3):25-31.温迪,孙庆文,潘国吉,等.清风藤属药用植物研究进展[J],贵州科学, 2016, 34(3):25-31.
    [40] Tang J F, Deng C Y, Lu Y C, Investigation on the distribution and utilization of the resources of Sabia parviflora in Southwest Guizhou[J], Guizhou Forest Sci Technol, 2002, 30(3):8-10.唐继方,邓朝义,卢永成,黔西南州小花清风藤资源分布及利用状况调查[J],贵州林业科技, 2002, 30(3):8-10.
    [41] Sui X Y, Huang Y, Tan Y, et al. Molecular authentication of the ethnomedicinal plant Sabia parviflora and its adulterants by DNA barcoding technique[J], Planta Med, 2011, 77, 492-496.
    [42] Sun Q W, Qi W N, Wang B. Microstructure characteristics and identification significance of leaf epidermis of medicinal plants from Sabia genus[J], J Chin Med Mater, 2013, 36(10):1594-1598.孙庆文,齐维娜,王波.清风藤属药用植物叶表皮特征及其鉴定学意义[J],中药材, 2013, 36(10):1594-1598.
    [43] Wang B, Qi W N, Sun Q W. Appearance and microscopic characteristics of four kinds of Sabia medicinal plants[J], Guizhou Agri Sci, 2014, 42(9):75-80.王波,齐维娜,孙庆文. 4种清风藤属药用植物的外观形态与显微特征[J],贵州农业科学, 2014, 42(9):75-80.
    [44] Liu K C, Zhang Y S. Identification of the microscopic characteristics of leaf epidermis of 9 medicinal plants of the Sabia genus[J], J Sichun Tradit Chin Med, 2015,33(7):106-109.刘科成,张银素.清风藤属9种药用植物的叶表皮显微特征统计的鉴定意义[J],四川中医, 2015, 33(7):106-109.
    [45] Wen D, Sun Q W, Chen J Z, et al. Stone cell characteristics of medicinal plants of the Sabia genus and its identification significance[J], J Chin Med Mater, 2016,39(9):1989-1992.温迪,孙庆文,陈敬忠,等.清风藤属药用植物石细胞特征及其鉴定学意义[J],中药材, 2016, 39(9):1989-1992.
    [46] Guizhou Science and Technology Press. Quality standard of Chinese herbal medicines and ethnic medicinal materials in Guizhou province[B], 2003.贵州科技出版社.?贵州省中药材、民族药材质量标准?[B], 2003年.
    [47] Chen X P, Yuan H F, Chou Y J, et al. Study on quality standard of Qing Feng Teng[J], China Pharm,2014, 23(24):68-71.陈骁鹏,袁华峰,仇雅静,等.清风藤质量标准研究[J],中国药业, 2014, 23(24):68-71.
    [48] Pan G J, Xu W F, Sun Q W, et al. Extraction process and content determination of total flavonoids from Sabia parviflora[J], West China J Pharm Sci, 2018, 33(3):295-300.潘国吉,徐文芬,孙庆文,等.小花清风藤总黄酮的提取工艺及其含量的测定[J],华西药学杂志, 2018, 33(3):295-300.
    [49] Liu Y R, Liang G Y, Zhang Y P. Determination of quercetin in Sabia parviflora by high performance liquid chromatography[J], Guizhou Med J, 2006,(4):363-364.刘易蓉,梁光义,张永萍.高效液相色谱法测定小花清风藤中榭皮素的含量[J],贵州医药, 2006,(4):363-364.
    [50] Liu Y R, Liang G Y, Zhang Y P. Study on extraction process of quercetin from Sabia parviflora[J], Guizhou Med J, 2006, 30(6):566-567.刘易蓉,梁光义,张永萍.小花清风藤中槲皮素的提取工艺研究[J],贵州医药, 2006, 30(6):566-567.
    [51] Zhang M, Yang J, Wei X, et al. Comparison of quercetin content in different parts of Sabia parviflora[J], Herald of Medicine, 2014, 33(10):1379-1380.张敏,杨剑,韦欣,等.贵州产小花清风藤不同部位槲皮素含量比较[J],医学导报, 2014, 33(10):1379-1380.
    [52] Liu Z H, Huang P, Xia G C. Content determination of oleanollc acid in Sabla parvlflora by HPLC[J], Chin J of Ethnomed Ethnopharm, 2015, 24(19):8-11.刘志海,黄沛,夏高春. HPLC测定小花清风藤中齐墩果酸的含量[J],中国民族民间医药, 2015, 24(19):8-11.
    [53] Liu Y R, Zhang Y P, Liang G Y, et al. Extraction process of oleanolic acid from Sabla parvlflora in Qingnan[J], China J Chin Mater Med, 2006, 31(16):1373-1374.刘易蓉,张永萍,梁光义,等.黔南小花清风藤中齐墩果酸的提取工艺[J],中国中药杂志, 2006, 31(16):1373-1374.
    [54] Liu Y R, Zhang Y P, Liang G Y, et al. Study on the extraction process of oleanolic acid from Sabla parvlflora[J], China Pharm, 2006, 15(14):33-34.刘易蓉,张永萍,梁光义,等.小花清风藤提取齐墩果酸工艺研究[J],中国药业, 2006, 15(14):33-34.

© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号

地址:北京市海淀区学院路29号 邮编:100083

电话:办公室:(+86 10)66554848;文献借阅、咨询服务、科技查新:66554700