哮喘急性发作的病例分析及药物治疗
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摘要
目的:为提高临床医生对支气管哮喘及其急性发作的认识,做出及时正确诊断并给予规范化治疗,以减少误诊和医疗资源的浪费。方法:分析2例哮喘急性发作的病例并进行总结。结果:患儿均属于哮喘的急性发作,在明确的诊断和正确治疗下病情好转,并给予长期规范化管理。结论:哮喘急性发作治疗的关键是缓解气道痉挛、消除气道炎症。尽早明确诊断并给予正确规范化治疗对哮喘的愈后有积极的影响。
Objective: To improve the clinician's knowledge of bronchial asthma and asthma exacerbation. make correct diagnosis and standardized treatment. so as to reduce the misdiagnosis and waste of medical resources. Methods: Two cases of asthma exacerbation were analyzed and outlined. Results: Both of the two cases were diagnosed as asthma exacerbation, and the condition was relieved due to the correct diagnosis and treatment In addition, the patients were given long-term standardized management Conclusion : The crucial steps for the treatment of asthma exacerbation are to relieve the spasm of bronchiole smooth muscle, and alleviate airway inflammation. Therefore, correct diagnosis and normative treatment has a positive impact on the prognosis of asthma.
Objective: To improve the clinician's knowledge of bronchial asthma and asthma exacerbation. make correct diagnosis and standardized treatment. so as to reduce the misdiagnosis and waste of medical resources. Methods: Two cases of asthma exacerbation were analyzed and outlined. Results: Both of the two cases were diagnosed as asthma exacerbation, and the condition was relieved due to the correct diagnosis and treatment In addition, the patients were given long-term standardized management Conclusion : The crucial steps for the treatment of asthma exacerbation are to relieve the spasm of bronchiole smooth muscle, and alleviate airway inflammation. Therefore, correct diagnosis and normative treatment has a positive impact on the prognosis of asthma.
引文
[1]Wong G W K,Kwon N,Hong J G,et al.Pediatric asthma control in Asia:Phase 2 of the Asthma Insights and Reality in Asia-Pacific(AIRIAP 2)survey[J].Allergy,2013,68(4):524-530.
[2]中华医学会儿科学分会呼吸学组.儿童支气管哮喘诊断与防治指南(2016年版)[J].中华儿科杂志,2016,54(3):167-181.
[3]Lin S,Jones R,Munsie J P,et al.Childhood asthma and indoor allergen exposure and sensitization in Buffalo,New York[J].International Journal of Hygiene&Environmental Health,2012,215(3):297-305.
[4]Beck A F,Huang B,Kercsmar C M,et al.Allergen Sensitization Profiles in a Population-Based Cohort of Children Hospitalized for Asthma[J].Ann Am Thorac Soc.2015,12(3):376-384.
[5]张玉娥,魏琳,单蓓兰,等.支气管哮喘患儿急性发作期血清免疫球蛋白E、免疫球蛋白G_4和白三烯B_4水平的临床研究[J].中华实用儿科临床杂志,2014,29(21):1625-1627.
[6]Gern J E.Virus/Allergen Interaction in Asthma Exacerbation[J].Annals of the American Thoracic Society,2015,12(Supp1.2):S137-S143.
[7]Carroll C,Stoltz P,Schramm C M,et al.Beta_2-adrenergic receptor polymorphisms affect response to treatment in children with severe asthma exacerbations[J].Chest,2009,135(5):1186-1192.
[8]陈爱欢,陈荣昌,湛洁谊,等.雾化吸入高剂量糖皮质激素对儿童中重度支气管哮喘急性发作的疗效[J].中华结核和呼吸杂志,2012,35(4):269-274.
[2]中华医学会儿科学分会呼吸学组.儿童支气管哮喘诊断与防治指南(2016年版)[J].中华儿科杂志,2016,54(3):167-181.
[3]Lin S,Jones R,Munsie J P,et al.Childhood asthma and indoor allergen exposure and sensitization in Buffalo,New York[J].International Journal of Hygiene&Environmental Health,2012,215(3):297-305.
[4]Beck A F,Huang B,Kercsmar C M,et al.Allergen Sensitization Profiles in a Population-Based Cohort of Children Hospitalized for Asthma[J].Ann Am Thorac Soc.2015,12(3):376-384.
[5]张玉娥,魏琳,单蓓兰,等.支气管哮喘患儿急性发作期血清免疫球蛋白E、免疫球蛋白G_4和白三烯B_4水平的临床研究[J].中华实用儿科临床杂志,2014,29(21):1625-1627.
[6]Gern J E.Virus/Allergen Interaction in Asthma Exacerbation[J].Annals of the American Thoracic Society,2015,12(Supp1.2):S137-S143.
[7]Carroll C,Stoltz P,Schramm C M,et al.Beta_2-adrenergic receptor polymorphisms affect response to treatment in children with severe asthma exacerbations[J].Chest,2009,135(5):1186-1192.
[8]陈爱欢,陈荣昌,湛洁谊,等.雾化吸入高剂量糖皮质激素对儿童中重度支气管哮喘急性发作的疗效[J].中华结核和呼吸杂志,2012,35(4):269-274.