1,5-双(苯并三氮唑)戊烷镉配合物的抑菌性研究
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摘要
以苯并三氮唑和1,5-二溴戊烷为原料,采用传统回流法合成1,5-双(苯并三氮唑)戊烷(BBTP)有机化合物.以自制的柔性1,5-双(苯并三氮唑)戊烷(BBTP)为桥联配体,以卤素离子(X-)或拟卤素离子(SCN-)为第二桥联配体,利用溶剂挥发法与硝酸镉反应成功得到四个镉配合物.通过红外光谱、热重分析等手段对配合物进行了全面的表征.此外,还研究了配体及其配合物对腐皮镰刀真菌生长的抑制作用,结果表明配合物的抑菌活性较配体的强.
Using benzotriazole and 1,5-dibromopentane as raw material,this experiment produced 1,5-bis(benzotriazole)pentane(BBTP)through the method of reflux.The self-assembly of Cd(NO3)2·4H2O with 1,5-bis(benzotriazole)pentane(BBTP)ligand and halogen ions(X-)or quasi halogen ion(SCN-)produce four Cd(Ⅱ)complexes,which are characterized by IR and TGA.Furthermore,the antibacterial activity of ligand and their complexes on the growth of fusarium solani have been studied.The results showed that complexes have relatively strong antibacterial activity than that of the ligand.
Using benzotriazole and 1,5-dibromopentane as raw material,this experiment produced 1,5-bis(benzotriazole)pentane(BBTP)through the method of reflux.The self-assembly of Cd(NO3)2·4H2O with 1,5-bis(benzotriazole)pentane(BBTP)ligand and halogen ions(X-)or quasi halogen ion(SCN-)produce four Cd(Ⅱ)complexes,which are characterized by IR and TGA.Furthermore,the antibacterial activity of ligand and their complexes on the growth of fusarium solani have been studied.The results showed that complexes have relatively strong antibacterial activity than that of the ligand.
引文
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[2]徐群杰,周国定,陆柱.苯并三氮唑和5-羧基苯并三氮唑对铜缓蚀作用的光电化学比较[J].中国有色金属学报,2001,11(5):925-929.
[3]史瑶,姚林辉,赵文芳,等.苯并三氮唑对硫增感溴化银乳剂的过增感效应[J].感光科学与光化学,2002,20(5):326-334.
[4]张胜涛,薛茗月,王艳波,等.苯并三氮唑缓蚀剂在铜表面覆盖行为的研究[J].腐蚀科学与防护技术,2006,18(5):313-316.
[5]张景玲,张新玲,周海晖,等.苯并三氮唑及其衍生物对铜的协同缓蚀效应[J].电镀与涂饰,2011,30(11):46-49.
[6]WANG Y,YI L,YANG X,et al.Synthesis,Crystal Structure,and Characterization of New Tetranuclear Ag(Ⅰ)Complexes with Triazole Bridges[J].Inorg Chem,2006,45:5822-5829.
[7]YAO Z F,GAN X,FU W F.The influence of the carbon double bond on the structure and photophysical properties of copper(Ⅰ)coordination polymers[J].Journal of Coord Chem,2009,62(11):1817-1826.
[8]MASSOUD S S,DEIFIK P J,BANKOLE P K,et al.Structural and magnetic characterization of a novel series of dinuclear Cu(Ⅱ)complexes bridging by 2,5-pyrazine dicarboxylate[J].Inorg Chim Acta,2010,363(5):1001-1007.
[9]TIAN L,NIU Z,YANG N,et al.Crystal structures and luminescent properties of zinc(Ⅱ)and cadmium(Ⅱ)compounds constructed from 5-sulfoisophthalic acid and flexible bis-triazole ligands[J].Inorg Chim Acta,2011,370(1):230-235.
[10]HAN S,LIU X Y,CAI Z F,et al.An unexpected coordination polymer containing one-dimensional chlorine-bridged copper(Ⅱ)magnetic chain induced by organic cation:Synthesis,crystal structure and magnetic properties[J].Inorg Chem Commun,2012,24:91-94.
[11]CAO D P,QIN L,YAO X Q,et al.Zheng.Synthesis,characterization and crystal structure of one Cu(Ⅱ)complex with flexible tetrapyridine and fatty acid ligand[J].Inorg Chem Commun,2013,29:27-29.
[12]YANG Y T,CHENG F X,TU C Z,et al.A novel(3,4)-connected Cd(Ⅱ)-coordination polymer with3-fold interpenetration assembled from 5-Nitrobenzene-1,2,3-tricarboxylate and flexible 1,6-bis(imidazol-1-yl)-hexane ligands[J].Inorg Chem Commun,2013,29:106-109.
[13]Hou H W,Meng X R,Song Y L,et al.Two-Dimensional Rhombohedral Grid Coordination Polymers[M(bbbt)2(NCS)2]n(M=Co,Mn,or Cd;bbbt=1,1′-(1,4-butanediyl)bis-1H-benzotriazole):Synthesis,Crystal Structures,and Third-Order Nonlinear Optical Properties[J].Inorg Chem,2002,41:4068-4075.
[14]MENG X R,SONG Y L,HOU H W,et al.Novel Pb and Zn Coordination Polymers:Synthesis,Molecular Structures,and Third-Order Nonlinear Optical Properties[J].Inorg Chem,2003,42:1306-1315.
[15]ZHOU J H,PENG Y F,ZHANG Y P,et al.Synthesis,Crystal Structure and Luminescent Properties of a Novel Cadmium Coordination Polymer with Unprecedented One-Dimensional Hetero-Triple-Stranded Chain[J].Inorg Chem Commun,2004,7:1181-1183.
[16]BSTING P,STEEL P J.Synthesis and X-ray Crystal Structures of Cobalt and Copper Complexes of 1,3-Bis(benzotriazolyl)propanes[J].Eur J Inorg Chem,2004(2):376-380.
[17]ZHOU J H,LIU X G,ZHANG Y P,et al.Synthesis,Structures and Luminescent Properties of Two Silver Supramolecular Isomers with One-Dimensional Concavo-Convex Chain and Dimer Metallacycle[J].Inorg Chem Commun,2006,9:216-219.
[18]ZHOU X L,MENG X R,CHENG W,et al.Crystal Structural,Electrochemical and Computational Studies of Two Cu(II)Complexes Formed by Benzotriazole Derivatives[J].Inorg Chim Acta,2007,360:3467-3474.
[19]MENG X R,LI J P,HOU H W,et al.Double Helix Chain Frameworks Constructed from Bis-Benzotriazole Building Blocks:Syntheses,Crystal Structures and Third-Order Nonlinear Optical Properties[J].J Mol Struct,2008,891:305-311.
[20]GAO X,ZHAI Q G,DUI X J,et al.Synthesis,Crystal Structure,and Characterizations of a 3D Cu(I)Organic-Inorganic Hybrid Solid with 1,6-Bi(benzotriazole)hexane Ligand[J].J Coord Chem,2010,63:214-222.
[21]HU M C,WANG Y,ZHAI Q G,et al.Synthesis,Crystal Structures,and Photoluminescence Properties of the Cu(Ⅰ)/X/α,ω-Bis(benzotriazole)alkane Hybrid Family(X=Cl,Br,I,and CN)[J].Inorg Chem,2009,8:1449-1468.
[22]GAO X,ZHAI Q G,LI S N,et al.Two Anionic[CuI6X7]n-n(X=Br and I)Chain-Based Organic-Inorganic Hybrid Solids with N-substituted Benzotriazole Ligands[J].J Solid State Chem,2010,183:1150-1158.
[23]高霞,张国春.1,5-双(苯并三氮唑)戊烷的合成和抑菌性研究[J].陕西科技大学学报,2016,34(2):107-111.