益生菌对猪大肠杆菌病防治作用的研究进展
|
摘要
动物大肠杆菌病是危害我国畜禽养殖行业的重要疾病,基于猪大肠杆菌病的病原学和流行特点,从益生菌的作用机理及其活性的限制性因素出发,以乳酸杆菌、双歧杆菌、肠球菌、酵母菌等常用益生菌的最新研究进展为根据,分析探索益生菌制剂代替抗生素在防治仔猪疾病中应用的可行性,显示了益生菌的潜力和优势,更好地推动畜禽养殖业的发展。
Animal colibacillosis is one of the major diseases that endanger the livestock and poultry breeding in our country. According to the pathogenic and epidemiological characteristics of porcine colibacillosis, the feasibility of the application of probiotics to piglet diseases is analyzed from the perspectives of the mechanism of action and activity limitation of probiotics, such as Lactobacillus, Bifidobacteria, Enterococcus and Yeast. The great potential and advantages of probiotics may promote the development of livestock and poultry breeding.
Animal colibacillosis is one of the major diseases that endanger the livestock and poultry breeding in our country. According to the pathogenic and epidemiological characteristics of porcine colibacillosis, the feasibility of the application of probiotics to piglet diseases is analyzed from the perspectives of the mechanism of action and activity limitation of probiotics, such as Lactobacillus, Bifidobacteria, Enterococcus and Yeast. The great potential and advantages of probiotics may promote the development of livestock and poultry breeding.
引文
[1] 姚淑红. 猪大肠杆菌病及其流行特点[J].山东畜牧兽医, 2016, 37(6):32.
[2] 谭娅, 史开志, 王婧, 等. 猪大肠杆菌病防治的研究进展[J].中国畜禽种业, 2016, 12(9):127-129.
[3] 刘志林. 益生菌对猪肠道菌群的调控研究进展[J].山东畜牧兽医, 2010, 31(3):71-73.
[4] Bhandari S K, Opapeju F O, Krause D O, et al. Dietary protein level and probiotic supplementation effects on piglet response to Escherichia coli K88 challenge: performance and gut microbial population[J].Livest Sci, 2010, 133(1-3):185-188.
[5] 侯成立, 季海峰, 周雨霞,等. 益生菌的作用机制及其在母猪生产中的应用[J].中国畜牧兽医, 2011, 38(7):20-22.
[6] Lindner C, Wahl B, Fohse L, et al. Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine[J].J Exp Med, 2012, 209(2):365-377.
[7] Pabst O, Cerovic V, Hornef M. Secretory IgA in the coordination of establishment and maintenance of the microbiota[J].Trends Immunol, 2016, 37(5):287-296.
[8] Ai W, Yan Y, Xiong S, et al. Enhanced protection against pulmonary mycobacterial challenge by chitosan-formulated polyepitope gene vaccine is associated with increased pulmonary secretory IgA and gamma-interferon+T cell responses[J].Microbiol Immunol, 2013, 57(3):224-235.
[9] Wu Y, Cui Z, Zhuang C, et al. Protective effects of Lactobacillus plantarum on epithelial barrier disruption caused by enterotoxigenic Escherichia coli in intestinal porcine epithelial cells[J].Vet Immunol Immunop, 2016, 172:55.
[10] 章文明, 汪海峰, 刘建新. 乳酸杆菌益生作用机制的研究进展[J].动物营养学报, 2012, 24(3):389-396.
[11] 陆克文, 姜平. 猪源乳酸菌对致病性大肠杆菌的体外抑制作用[J].畜牧与兽医, 2011, 43(11):51-53.
[12] 凌晨, 蒋光邻, 钱莹, 等. 猪源乳酸杆菌对致病性沙门菌、大肠埃希菌黏附仔猪小肠上皮细胞的影响[J].西北农业学报, 2013, 22(9):18-23.
[13] Kapila R, Sebastian R, Vivek P V D, et al. Comparison of innate immune activation after prolonged feeding of milk fermented with three species of Lactobacilli[J].Microbiol Immunol, 2013, 57(11):778-784.
[14] Kotani Y, Kunisawa J, Suzuki Y, et al. Role of Lactobacillus pentosus Strain b240 and the toll-like receptor 2 axis in Peyer's patch dendritic cell-mediated immunoglobulin a enhancement[J].Plos One, 2014, 9(3):e91857.
[15] 王四新, 季海峰, 刘辉, 等. 猪源发酵乳酸杆菌对保育猪生长性能、养分表观消化率、粪便微生物数量及血清免疫指标的影响[J].中国畜牧兽医, 2016, 43(5):1215-1220.
[16] Markowiak P, Slizewska K. The role of probiotics, prebiotics and synbiotics in animal nutrition[J].Gut Pathog, 2018, 10:21.
[17] 张志龙. 乳酸杆菌对仔猪生长效果的试验[J].湖南畜牧兽医, 2003(2) : 4-5.
[18] 黄红莹, 马远方, 杜耀武, 等. 青春型双歧杆菌的抗菌作用及其成分分析[J].中国微生态学杂志, 2006, 18(2):100-101.
[19] 史崇明. 双歧杆菌活菌制剂对肝硬化患者肠道菌群及内毒素血症的影响[J].临床消化病杂志, 2002, 14(6):266.
[20] 刘国荣, 潘伟好, 畅晓渊, 等. 双歧杆菌的黏附特性及其对肠道致病菌的体外拮抗作用[J].微生物学通报, 2009, 36(5):716-721.
[21] Bertkova I, Hijova E, Chmelarova A, et al. The effect of probiotic microorganisms and bioactive compounds on chemically induced carcinogenesis in rats[J].Neoplasma, 2010, 57(5):422.
[22] Yen C H, Kuo Y W, Tseng Y H, et al. Beneficial effects of fructo-oligosaccharides supplementation on fecal bifidobacteria and index of peroxidation status in constipated nursing-home residents-a placebo-controlled, diet-controlled trial[J].Nutrition, 2011, 27(3):323-328.
[23] Marcinakov M, Klingberg T D, Laukov A, et al. The effect of pH, bile and calcium on the adhesion ability of probiotic enterococci of animal origin to the porcine jejunal epithelial cell line IPEC-J2[J].Anaerobe, 2010, 16(2):120.
[24] Ross G R, Gusils C, Oliszewski R, et al. Effects of probiotic administration in swine[J].J Biosci Bioeng, 2010, 109(6):545-549.
[25] Jin L, Marquardt R, Zhao X. A strain of Enterococcus faecium (18C23) inhibits adhesion of enterotoxigenic Escherichia coli K88 to porcine small intestine mucus[J].Appl Environ Microb, 2000, 66(10):4200-4204.
[26] 黄怡, 黄琴, 崔志文, 等. 新生仔猪口服屎肠球菌对其肠道菌群组成及化学屏障的影响[J].中国兽医学报, 2012, 32(7):1007-1010.
[27] 史自涛, 姚焰础, 江山, 等. 粪肠球菌替代抗生素对断奶仔猪生长性能、腹泻率、血液生化指标和免疫器官的影响[J].动物营养学报, 2015, 27(6):1832-1840.
[28] Mallo J J. The addition of Enterococcus faecium to diet improves piglet's intestinal microbiota and performance[J].Livest Sci, 2010, 133(1):176-178.
[29] B?hmer B M, Kramer W, Roth-maier D A. Dietary probiotic supplementation and resulting effects on performance, health status, and microbial characteristics of primiparous sows[J].J Anim Physiol An N, 2006, 90(7-8):309-315.
[30] 周淑芹, 孙文志. 酵母培养物与抗生素对肉仔鸡生长性能及免疫机能影响的研究[J].畜牧与兽医, 2004, 36(11):9-11.
[31] Khatri I, Tomar R, Ganesan K, et al. Complete genome sequence and comparative genomics of the probiotic yeast Saccharomyces boulardii[J].Sci Rep-UK, 2017, 7(1):371.
[32] Orlean P. Architecture and biosynthesis of the Saccharomyces cerevisiae cell wall[J].Genetics, 2012, 192(3):775.
[33] Wojcik R. Reactivity of the immunological system of rats stimulated with Biolex-Beta HP after cyclophosphamide immunosuppression[J].Cent Eur J Immunol, 2014, 39(1):60-69.
[34] 赵瑜, 何闪, Bon M L. 酵母菌能够平衡哺乳仔猪断奶时胃肠道菌群组成[J].国外畜牧学(猪与禽), 2014, 34(12):6-8.
[35] 张宏福, 徐秀容, 卢庆萍, 等. 异麦芽低聚糖对早期断奶仔猪肠道主要菌群的影响[J].动物营养学报, 2001, 13(3):47-51.
[36] 韩春艳, 侯雨文, 刘志伟, 等. 不同日龄添加乳酸杆菌对早期断奶仔猪生长性能的影响[J].畜禽业, 2004, (7):12-13.
[37] 汪川, 张朝武. 以益生菌为载体的基因工程疫苗研究进展[J].卫生研究, 2008, 37(1):118-122.
[2] 谭娅, 史开志, 王婧, 等. 猪大肠杆菌病防治的研究进展[J].中国畜禽种业, 2016, 12(9):127-129.
[3] 刘志林. 益生菌对猪肠道菌群的调控研究进展[J].山东畜牧兽医, 2010, 31(3):71-73.
[4] Bhandari S K, Opapeju F O, Krause D O, et al. Dietary protein level and probiotic supplementation effects on piglet response to Escherichia coli K88 challenge: performance and gut microbial population[J].Livest Sci, 2010, 133(1-3):185-188.
[5] 侯成立, 季海峰, 周雨霞,等. 益生菌的作用机制及其在母猪生产中的应用[J].中国畜牧兽医, 2011, 38(7):20-22.
[6] Lindner C, Wahl B, Fohse L, et al. Age, microbiota, and T cells shape diverse individual IgA repertoires in the intestine[J].J Exp Med, 2012, 209(2):365-377.
[7] Pabst O, Cerovic V, Hornef M. Secretory IgA in the coordination of establishment and maintenance of the microbiota[J].Trends Immunol, 2016, 37(5):287-296.
[8] Ai W, Yan Y, Xiong S, et al. Enhanced protection against pulmonary mycobacterial challenge by chitosan-formulated polyepitope gene vaccine is associated with increased pulmonary secretory IgA and gamma-interferon+T cell responses[J].Microbiol Immunol, 2013, 57(3):224-235.
[9] Wu Y, Cui Z, Zhuang C, et al. Protective effects of Lactobacillus plantarum on epithelial barrier disruption caused by enterotoxigenic Escherichia coli in intestinal porcine epithelial cells[J].Vet Immunol Immunop, 2016, 172:55.
[10] 章文明, 汪海峰, 刘建新. 乳酸杆菌益生作用机制的研究进展[J].动物营养学报, 2012, 24(3):389-396.
[11] 陆克文, 姜平. 猪源乳酸菌对致病性大肠杆菌的体外抑制作用[J].畜牧与兽医, 2011, 43(11):51-53.
[12] 凌晨, 蒋光邻, 钱莹, 等. 猪源乳酸杆菌对致病性沙门菌、大肠埃希菌黏附仔猪小肠上皮细胞的影响[J].西北农业学报, 2013, 22(9):18-23.
[13] Kapila R, Sebastian R, Vivek P V D, et al. Comparison of innate immune activation after prolonged feeding of milk fermented with three species of Lactobacilli[J].Microbiol Immunol, 2013, 57(11):778-784.
[14] Kotani Y, Kunisawa J, Suzuki Y, et al. Role of Lactobacillus pentosus Strain b240 and the toll-like receptor 2 axis in Peyer's patch dendritic cell-mediated immunoglobulin a enhancement[J].Plos One, 2014, 9(3):e91857.
[15] 王四新, 季海峰, 刘辉, 等. 猪源发酵乳酸杆菌对保育猪生长性能、养分表观消化率、粪便微生物数量及血清免疫指标的影响[J].中国畜牧兽医, 2016, 43(5):1215-1220.
[16] Markowiak P, Slizewska K. The role of probiotics, prebiotics and synbiotics in animal nutrition[J].Gut Pathog, 2018, 10:21.
[17] 张志龙. 乳酸杆菌对仔猪生长效果的试验[J].湖南畜牧兽医, 2003(2) : 4-5.
[18] 黄红莹, 马远方, 杜耀武, 等. 青春型双歧杆菌的抗菌作用及其成分分析[J].中国微生态学杂志, 2006, 18(2):100-101.
[19] 史崇明. 双歧杆菌活菌制剂对肝硬化患者肠道菌群及内毒素血症的影响[J].临床消化病杂志, 2002, 14(6):266.
[20] 刘国荣, 潘伟好, 畅晓渊, 等. 双歧杆菌的黏附特性及其对肠道致病菌的体外拮抗作用[J].微生物学通报, 2009, 36(5):716-721.
[21] Bertkova I, Hijova E, Chmelarova A, et al. The effect of probiotic microorganisms and bioactive compounds on chemically induced carcinogenesis in rats[J].Neoplasma, 2010, 57(5):422.
[22] Yen C H, Kuo Y W, Tseng Y H, et al. Beneficial effects of fructo-oligosaccharides supplementation on fecal bifidobacteria and index of peroxidation status in constipated nursing-home residents-a placebo-controlled, diet-controlled trial[J].Nutrition, 2011, 27(3):323-328.
[23] Marcinakov M, Klingberg T D, Laukov A, et al. The effect of pH, bile and calcium on the adhesion ability of probiotic enterococci of animal origin to the porcine jejunal epithelial cell line IPEC-J2[J].Anaerobe, 2010, 16(2):120.
[24] Ross G R, Gusils C, Oliszewski R, et al. Effects of probiotic administration in swine[J].J Biosci Bioeng, 2010, 109(6):545-549.
[25] Jin L, Marquardt R, Zhao X. A strain of Enterococcus faecium (18C23) inhibits adhesion of enterotoxigenic Escherichia coli K88 to porcine small intestine mucus[J].Appl Environ Microb, 2000, 66(10):4200-4204.
[26] 黄怡, 黄琴, 崔志文, 等. 新生仔猪口服屎肠球菌对其肠道菌群组成及化学屏障的影响[J].中国兽医学报, 2012, 32(7):1007-1010.
[27] 史自涛, 姚焰础, 江山, 等. 粪肠球菌替代抗生素对断奶仔猪生长性能、腹泻率、血液生化指标和免疫器官的影响[J].动物营养学报, 2015, 27(6):1832-1840.
[28] Mallo J J. The addition of Enterococcus faecium to diet improves piglet's intestinal microbiota and performance[J].Livest Sci, 2010, 133(1):176-178.
[29] B?hmer B M, Kramer W, Roth-maier D A. Dietary probiotic supplementation and resulting effects on performance, health status, and microbial characteristics of primiparous sows[J].J Anim Physiol An N, 2006, 90(7-8):309-315.
[30] 周淑芹, 孙文志. 酵母培养物与抗生素对肉仔鸡生长性能及免疫机能影响的研究[J].畜牧与兽医, 2004, 36(11):9-11.
[31] Khatri I, Tomar R, Ganesan K, et al. Complete genome sequence and comparative genomics of the probiotic yeast Saccharomyces boulardii[J].Sci Rep-UK, 2017, 7(1):371.
[32] Orlean P. Architecture and biosynthesis of the Saccharomyces cerevisiae cell wall[J].Genetics, 2012, 192(3):775.
[33] Wojcik R. Reactivity of the immunological system of rats stimulated with Biolex-Beta HP after cyclophosphamide immunosuppression[J].Cent Eur J Immunol, 2014, 39(1):60-69.
[34] 赵瑜, 何闪, Bon M L. 酵母菌能够平衡哺乳仔猪断奶时胃肠道菌群组成[J].国外畜牧学(猪与禽), 2014, 34(12):6-8.
[35] 张宏福, 徐秀容, 卢庆萍, 等. 异麦芽低聚糖对早期断奶仔猪肠道主要菌群的影响[J].动物营养学报, 2001, 13(3):47-51.
[36] 韩春艳, 侯雨文, 刘志伟, 等. 不同日龄添加乳酸杆菌对早期断奶仔猪生长性能的影响[J].畜禽业, 2004, (7):12-13.
[37] 汪川, 张朝武. 以益生菌为载体的基因工程疫苗研究进展[J].卫生研究, 2008, 37(1):118-122.