摘要
目的探讨磁共振乳腺非特殊类型浸润性癌动态增强表现与预后因子ER、PR、HER2、细胞核增殖抗原Ki-67、抑癌基因p53、上皮生长因子EGFR、细胞角蛋白CK5/6、术区淋巴结的相关性。方法分析80例乳腺非特殊类型浸润性癌患者的术前动态增强MR探讨特点与预后因子的相关性。结果乳腺非特殊类型浸润性癌形态不规则与Ki-67阳性表达存在正相关;环形强化与术区淋巴结阳性表达存在正相关;动态增强时间-信号强度曲线的Ⅲ型曲线与CK5/6阳性表达存在正相关;病灶中心层面最大长径2-5cm组病例与Ki-67、p53、术区淋巴结的阳性表达存在正相关。结论乳腺非特殊类型浸润性癌的动态增强特点与部分预后因子有显著相关性,磁共振动态增强检查是临床选择治疗方案的重要参考。
引文
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