活血利咽汤治疗慢性咽喉炎疗效及对患者血清SIgA水平影响的研究
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摘要
目的:探讨自拟活血利咽汤治疗慢性咽喉炎效果及对患者血清SIgA水平的影响。方法:选取我院收治的慢性咽喉炎患者100例,随机分为两组,对照组应用口服金嗓利咽丸治疗,研究组应用自拟活血利咽汤治疗,分析两组患者的治疗效果、炎症因子水平变化以及临床症状改善情况。结果:研究组的治疗有效率为96.0%,复发率为12.0%;对照组患者的治疗有效率为78.0%,复发率为28.0%,研究组的患者治疗及复发情况要优于对照组(P<0.05)。研究组与对照组患者在接受治疗1个疗程后与治疗前相比临床体征均有明显改善(P<0.05),研究组与对照组治疗后相比研究组咽干、咽痛、异物改善情况更明显(P<0.05)。研究组与对照组患者在接受治疗1个疗程后与治疗前相比炎症因子水平变化均有改善(P<0.05),研究组与对照组治疗后相比改善情况更明显(P<0.05)。研究组与对照组治疗后相比研究组倦怠懒言、腹胀便溏、舌质舌苔、脉象改善情况更明显(P<0.05)。两组患者治疗前SIgA含量无明显变化,治疗后研究组SIgA含量为(25.5±3.7)g/L,对照组SIgA含量为(22.3±3.8)g/L,研究组与对照组治疗后相比研究组SIgA含量改善情况更明显(P<0.05)。结论:在慢性咽炎的治疗过程当中,自拟活血利咽汤的治疗效果较理想。
引文
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[2]朱明馨,金凤,杨丹枫.肃肺利咽汤治疗儿童喉源性咳嗽风邪犯肺证30例[J].辽宁中医杂志,2016,30(8):1657-1658.
[3]Hotta O,Tanaka A,Torigoe A,et al.Involvement of chronic epipharyngitis in autoimmune(auto-inflammatory)syndrome induced by adjuvants(ASIA)[J].Immunologic Research,2016:1-6.
[4]Jara L J,Izquierdo E,Medina G.Is the immune neuroendocrine system the connection between epipharyngitis and chronic fatigue syndrome induced by HPV vaccine?:Editorial[J].Immunologic Research,2017,65(1):1-3.
[5]李娜,杨丰文,陆中英,等.蓝芩口服液治疗慢性咽炎随机对照试验的系统评价和Meta分析[J].中国中药杂志,2017,42(8):1489-1494.
[6]陈建军,殷善开,刘世喜,等.冰连清咽喷雾剂治疗急性咽炎及慢性咽炎急性发作多中心随机对照研究[J].临床耳鼻咽喉头颈外科杂志,2018,20(1):1-6.
[7]Pham L L,Bourayou R,Maghraoui-Slim V,et al.25-Laryngitis,Epiglottitis and Pharyngitis[J].Infectious Diseases,2017,26(23):229-235.
[8]Czerwińska ME,Swierczewska A,Wozniak M,et al.Bioassay-guided isolation of iridoids and phenylpropanoids from aerial parts of lamium album and their anti-inflammatory activity in human neutrophils[J].Planta Medica,2017,83(12/13):1011-1019.
[9]曹景诚,梁茂新.慢性咽炎辨证存在问题及对策[J].中华中医药杂志,2016,33(4):1332-1335.
[10]王慧敏,余文发,周航,等.中医辨证治疗慢性咽炎临床疗效[J].陕西中医,2017,38(4):487-489.
[11]张驰,杜锦朵,冉程.疏肝祛瘀化痰汤配合西药治疗慢性咽喉炎疗效观察[J].陕西中医,2016,37(3):316-317.
[12]张丹红,董春梅.滋阴活血利咽汤用于慢性咽炎患者治疗中的临床效果[J].双足与保健,2017,35(3):36-38.
[13]雷剑波,荣堃,杨丽,等.养阴利咽饮联合玉液散吹喉治疗阴虚肺燥型慢性咽炎效果及对血清炎症因子水平的影响[J].现代中西医结合杂志,2016,25(27):3041-3044.
[14]郭维娟.金莲清热泡腾片雾化吸入治疗慢性咽炎效果观察[J].临床合理用药杂志,2017,10(13):70-71.
[15]梁祖文.利咽汤治疗慢性咽炎70例的临床效果评价[J].北方药学,2016,13(12):104-105.
[16]Krivan G,Chernyshova L,Kostyuchenko L,et al.Amulticentre study on the efficacy,safety and pharmacokinetics of IqYmune,a highly purified 10%liquid intravenous immunoglobulin,in patients with primary immune deficiency[J].Journal of Clinical Immunology,2017,37(6):539-547.