摘要
目的探讨ALCPS治疗对TH患者预后的影响。方法选取2014年3月至2017年3月我院收治的TH患者100例,依据随机数字表法分为ALCPS组和VPS组,ALCPS组给予ALCPS治疗,VPS组给予VPS治疗,比较两组治疗疗效、并发症、ADL得分和NSE、S100β水平。结果 ALCPS组术后血清NSE、S100β水平明显低于VPS组,差异有统计学意义(P <0. 05); ALCPS组治疗有效率明显高于VPS组,差异有统计学意义(P <0. 05); ALCPS组并发症发生率明显低于VPS组,差异有统计学意义(P <0. 05); ALCPS组术后3、6个月ADL得分明显高于PS组,差异有统计学意义(P <0. 05)。结论 ALCPS治疗可有效降低TH患者血清NSE、S100β水平及并发症发生风险,可有效提高患者的治疗疗效和生活质量,有利于改善患者的预后,值得临床作进一步推广。
Objective The effect of ALCPS on prognosis of TH was studied. Methods A total of 100 patients with TH admitted to our hospital from March 2014 and March 2017 were selected randomly,and all the patients were divided into ALCPS group(50 cases) and VPS(50 cases). ALCPS group was treated with ALCPS and VPS group was treated with VPS,respectively. The efficacy,complications,ADL score,NSE and S100β levels were compared between two groups. Results Serum NSE,S100β levels in ALCPS group after surgery were significantly lower than those before surgery,with statistically significant difference(P < 0. 05). The effective rate of ALCPS group was significantly higher than that of VPS group,with statistically significant difference(P <0. 05). The complication rate of ALCPS group was significantly lower than that of VPS group,with statistically significant difference(P < 0. 05).ADL scores of ALCPS group at 3 months and 6 months after operation were significantly lower than those before operation,and the difference was statistically significant(P <0. 05). Conclusion ALCPS treatment can effectively reduce the serum NSE,S100 beta levels and the risk of complications in patients with TH,and it is beneficial to improve the prognosis of the patients. So it's worth of further clinical promotion.
引文
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