孕产妇脑静脉血栓的磁共振应用及临床分析
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摘要
目的探讨孕产妇脑静脉血栓的临床特点及磁共振成像在孕产妇脑静脉血栓中的应用价值。方法回顾性分析本院25例孕产妇脑静脉血栓患者的临床特点,分别对患者进行治疗前及治疗后磁共振常规及静脉血管成像扫描,使用配对t检验对治疗前后磁共振静脉血管成像信号特点进行统计学分析,以P<0.05为差异有统计学意义。采用四格表,以DSA为金标准,观察其灵敏度及特异度。结果磁共振MRV对孕产妇脑静脉血栓的灵敏度为88%,特异度为100%;治疗前后MRV信号特点变化P<0.05,差异有统计学意义。25例患者中孕晚期2例,产褥期(剖宫产17例,自然分娩6例)23例。结论孕产妇脑静脉血栓以发生于剖宫产后多见,临床上缺乏明显特异性表现。磁共振静脉血管成像检查作为无创性检查有较高的灵敏度及特异度,可以为临床治疗及治疗疗效的判定提供可靠的影像评价指标,为临床后续治疗提供参考及制定治疗方案。
Objective To explore the clinical value and clinical value of magnetic resonance imaging(MRI)in the diagnosis of cerebral venous thrombosis in pregnant women. Methods Retrospective analysis of 25 cases of maternal clinical characteristics of patients with cerebral venous thrombosis, treatment of patients before and after treatment respectively conventional and veins of magnetic resonance imaging scans, using a paired t test for vein imaging signal characteristics before and after treatment were statistically analyzed,with P < 0.05 for the difference was statistically significant. The sensitivity and specificity were observed with DSA as the gold standard.Results The sensitivity and specificity of MRV to maternal cerebral venous thrombosis was 88% and 100%. The changes of MRV signal characteristics before and after treatment(P < 0.05)were statistically significant. There were 2 cases of late pregnancy and 23 cases of natural childbirth(17 cases of cesarean section and 6 cases of natural childbirth) Conclusion Cerebral venous thrombosis in pregnant and parturient women is more common after cesarean section, which lacks obvious specificity in clinic. As a non-invasive examination,magnetic resonance venography has high sensitivity and specificity. It can provide reliable imaging evaluation index for clinical treatment and therapeutic efficacy evaluation, and provide reference for clinical follow-up treatment and formulate treatment plan.
Objective To explore the clinical value and clinical value of magnetic resonance imaging(MRI)in the diagnosis of cerebral venous thrombosis in pregnant women. Methods Retrospective analysis of 25 cases of maternal clinical characteristics of patients with cerebral venous thrombosis, treatment of patients before and after treatment respectively conventional and veins of magnetic resonance imaging scans, using a paired t test for vein imaging signal characteristics before and after treatment were statistically analyzed,with P < 0.05 for the difference was statistically significant. The sensitivity and specificity were observed with DSA as the gold standard.Results The sensitivity and specificity of MRV to maternal cerebral venous thrombosis was 88% and 100%. The changes of MRV signal characteristics before and after treatment(P < 0.05)were statistically significant. There were 2 cases of late pregnancy and 23 cases of natural childbirth(17 cases of cesarean section and 6 cases of natural childbirth) Conclusion Cerebral venous thrombosis in pregnant and parturient women is more common after cesarean section, which lacks obvious specificity in clinic. As a non-invasive examination,magnetic resonance venography has high sensitivity and specificity. It can provide reliable imaging evaluation index for clinical treatment and therapeutic efficacy evaluation, and provide reference for clinical follow-up treatment and formulate treatment plan.
引文
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[3]徐伟华,杨金伟,张童予,等.脑静脉窦血栓形成的CT与MRI诊断价值分析[J].影像研究与医学应用, 2018,2(13):45-47.
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[7]姚炯涛.血浆纤维蛋白原及D-二聚体监测对进展性脑卒中的诊断价值[J].河南医学研究, 2018,27(3):34-36.
[8]刘宇庆,郭莉莎.妊娠高血压并发脑静脉窦血栓形成34例临床分析[J].新疆医学, 2012,42(4):46-48.
[2]王亚洁,曾友华.孕产妇颅内静脉窦血栓形成的临床特点及危险因素分析[J].中国医师杂志, 2017, 19(6):903-905.
[3]徐伟华,杨金伟,张童予,等.脑静脉窦血栓形成的CT与MRI诊断价值分析[J].影像研究与医学应用, 2018,2(13):45-47.
[4]吕卫琴,李晓琴,倪妍.围生期颅内静脉窦血栓形成8例临床分析[J].中国实用医药, 2013, 8(15):173-174.
[5]Linn J. Imaging of Cerebral Venous and Sinus Thrombosis[M]. Springer NewYork, 2016,6(12):56-58.
[6]赵永军.脑静脉窦血栓形成的诊治分析[J].中国医药科学, 2012, 2(18):223-223.
[7]姚炯涛.血浆纤维蛋白原及D-二聚体监测对进展性脑卒中的诊断价值[J].河南医学研究, 2018,27(3):34-36.
[8]刘宇庆,郭莉莎.妊娠高血压并发脑静脉窦血栓形成34例临床分析[J].新疆医学, 2012,42(4):46-48.