多层螺旋CT联合肿瘤相关抗原对肺结核合并肺癌的诊断价值
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摘要
目的探寻多层螺旋CT联合肿瘤相关抗原对肺结核合并肺癌的诊断价值。方法选择我院2013年1月至2016年12月住院治疗的肺结核合并肺癌及继发型肺结核患者各50例作为研究对象,对其资料进行回顾性分析。结果多层螺旋CT诊断肺结核合并肺癌的敏感性较高,但特异度较低;而肿瘤相关抗原诊断肺结核合并肺癌的敏感性较低,特异度较高;两者联合可以提高肺结核合并肺癌的诊断敏感性。结论多层螺旋CT与肿瘤相关抗原联合诊断能及早确诊肺结核合并肺癌,有效避免误诊、漏诊,有助于提高患者生存率。
Objective To explore the diagnostic value of multi-slice spiral CT combined with tumor-associated antigen in pulmonary tuberculosis with lung cancer.MethodsChoose tuberculosis with lung cancer and secondary tuberculosis patients in our hospital in January 2013 to December 2016 hospitalized each 50 cases as the research object,its data were retrospectively analyzed.Results Multi-slice spiral CT diagnosis of pulmonary tuberculosis with lung cancer is more sensitive,but the specificity is low.The tumorassociated antigen diagnosis of pulmonary tuberculosis with lung cancer is less sensitive,specificity is higher.The combination of the two can improve the diagnostic sensitivity of pulmonary tuberculosis with lung cancer.Conclusion Multi-slice spiral CT combined with tumor-associated antigen can diagnose pulmonary tuberculosis with lung cancer,effectively avoid misdiagnosis,help improve patient survival.
Objective To explore the diagnostic value of multi-slice spiral CT combined with tumor-associated antigen in pulmonary tuberculosis with lung cancer.MethodsChoose tuberculosis with lung cancer and secondary tuberculosis patients in our hospital in January 2013 to December 2016 hospitalized each 50 cases as the research object,its data were retrospectively analyzed.Results Multi-slice spiral CT diagnosis of pulmonary tuberculosis with lung cancer is more sensitive,but the specificity is low.The tumorassociated antigen diagnosis of pulmonary tuberculosis with lung cancer is less sensitive,specificity is higher.The combination of the two can improve the diagnostic sensitivity of pulmonary tuberculosis with lung cancer.Conclusion Multi-slice spiral CT combined with tumor-associated antigen can diagnose pulmonary tuberculosis with lung cancer,effectively avoid misdiagnosis,help improve patient survival.
引文
[1]赵铭,陈晓峰,刘鸿程,等.肺结核合并肺癌的危险因素及预后分析[J].实用医学杂志,2010,8(11):1951-1953.
[2]Mohebbi HA,Saburi A,Bagheri MH,et al.A complicated case of lung cancer and pulmonary tuberculosis initially presented with painful scapular metastasis in other side[J].Chin German J Clin Oncol,2012,11(5):294-296.
[3]Wu CY,Hu HY,Pu CY,e t al.Pulmonary tuberculosis in-creases the risk of lung cancer[J].Cancer,2011,117(3):618-624.
[4]Christopoulos A,Saif MW,Sarris EG,et al.Epidemiology of active tuberculosis in lung cancer patients:a systematic review[J].Clin Respir J,2014,8(4):375-381.
[5]梁伟强,喻延,吴泽龙.支气管镜刷检薄层液基细胞学检查在肺癌诊断中的临床价值[J].现代诊断与治疗,2012,23(8):1127-1128.
[6]中华医学会结核病学分会.肺结核诊断和治疗指南[J].中国实用乡村医生杂志,2013,20(2):7-10.
[7]朱琦,孙学智,曾洁,等.76例肺癌合并肺结核临床特点分析[J].临床肺科杂志,2011,16(8):1233-1234.
[8]Zhi Z,You min P,Feng wei G,et al.Multimodality FDG PET/CT appearance of pulmonary tuberculoma mimic-king lung cancer and pathologic correlation in a tuberculosisendemic country[J].Southern Med J,2011,104(6):440-445.
[9]王昌盛,代敏,任建松,等.中国2008年肺癌发病、死亡和患病情况的估计及预测[J].中华流行病学杂志,2012,33(4):391-394.
[10]吕章春,李可,黄金莲,等.浙江省永康市2008-2010年肺癌发病分析[J].中国肿瘤,2013,22(9):706-708.
[11]古颖春,宋业琳,刘玉峰.肺结核合并肺癌患者的临床特征及预后影响因素[J].中华医学杂志,2014,94(36):2838-2840.
[12]阮军忠,王子彤,李世业,等.肺结核合并肺癌89例临床分析[J].中国防痨杂志,2008,30(5):448.
[13]张越野.肺结核合并肺癌早期诊疗效果观察[J].中国保健营养,2013,24(3):675-676.
[14]王宏,贾文霄.多层螺旋CT在肺结核诊断和鉴别诊断中的应用价值[J].中国CT和MRI杂志,2010,8(5):34-38.
[15]舒凯,肖立珠,范子田,等.痰液肿瘤标志物在中老年肺结核合并肺癌早期诊断中的应用价值[J].实用医学杂志,2012,28(19):3243-3245.
[16]曹丹庆,蔡祖龙.全身CT诊断学[M].北京:人民军医出版社,2004:361-388.
[17]周连坤,俊玲.老年人肺癌3 5例误诊分析[J].临床肺科杂志,2009,14(10):1395.
[18]李传资,陈向红,黄菁慧,等.肺结核合并肺癌的临床表现及其肺内占位CT特征对比研究[J].实用医学杂志,2010,26(13):2401-2403.
[19]Indranath Ghosh,Debojyoti Bhattacharjee,Anjan Kumar Das.Diagnostic Role of Tumour Markers CEA,CA15-3,CA19-9 and CA125 in Lung Cancer[J].Indian J Clin Biochem,2013,28(1):24-29.
[20]刘喆,朱允中,张新勇,等.多项肿瘤标志物在肺癌诊断中的应用[J].北京医学,2002,24(6):384-387.
[21]张洁,陈正福,景欣等.血清CEA和CA125联合检测在肺结核及肺癌诊断中价值探讨[J].航空航天医学杂志,2011,22(11):1334-1335.
[2]Mohebbi HA,Saburi A,Bagheri MH,et al.A complicated case of lung cancer and pulmonary tuberculosis initially presented with painful scapular metastasis in other side[J].Chin German J Clin Oncol,2012,11(5):294-296.
[3]Wu CY,Hu HY,Pu CY,e t al.Pulmonary tuberculosis in-creases the risk of lung cancer[J].Cancer,2011,117(3):618-624.
[4]Christopoulos A,Saif MW,Sarris EG,et al.Epidemiology of active tuberculosis in lung cancer patients:a systematic review[J].Clin Respir J,2014,8(4):375-381.
[5]梁伟强,喻延,吴泽龙.支气管镜刷检薄层液基细胞学检查在肺癌诊断中的临床价值[J].现代诊断与治疗,2012,23(8):1127-1128.
[6]中华医学会结核病学分会.肺结核诊断和治疗指南[J].中国实用乡村医生杂志,2013,20(2):7-10.
[7]朱琦,孙学智,曾洁,等.76例肺癌合并肺结核临床特点分析[J].临床肺科杂志,2011,16(8):1233-1234.
[8]Zhi Z,You min P,Feng wei G,et al.Multimodality FDG PET/CT appearance of pulmonary tuberculoma mimic-king lung cancer and pathologic correlation in a tuberculosisendemic country[J].Southern Med J,2011,104(6):440-445.
[9]王昌盛,代敏,任建松,等.中国2008年肺癌发病、死亡和患病情况的估计及预测[J].中华流行病学杂志,2012,33(4):391-394.
[10]吕章春,李可,黄金莲,等.浙江省永康市2008-2010年肺癌发病分析[J].中国肿瘤,2013,22(9):706-708.
[11]古颖春,宋业琳,刘玉峰.肺结核合并肺癌患者的临床特征及预后影响因素[J].中华医学杂志,2014,94(36):2838-2840.
[12]阮军忠,王子彤,李世业,等.肺结核合并肺癌89例临床分析[J].中国防痨杂志,2008,30(5):448.
[13]张越野.肺结核合并肺癌早期诊疗效果观察[J].中国保健营养,2013,24(3):675-676.
[14]王宏,贾文霄.多层螺旋CT在肺结核诊断和鉴别诊断中的应用价值[J].中国CT和MRI杂志,2010,8(5):34-38.
[15]舒凯,肖立珠,范子田,等.痰液肿瘤标志物在中老年肺结核合并肺癌早期诊断中的应用价值[J].实用医学杂志,2012,28(19):3243-3245.
[16]曹丹庆,蔡祖龙.全身CT诊断学[M].北京:人民军医出版社,2004:361-388.
[17]周连坤,俊玲.老年人肺癌3 5例误诊分析[J].临床肺科杂志,2009,14(10):1395.
[18]李传资,陈向红,黄菁慧,等.肺结核合并肺癌的临床表现及其肺内占位CT特征对比研究[J].实用医学杂志,2010,26(13):2401-2403.
[19]Indranath Ghosh,Debojyoti Bhattacharjee,Anjan Kumar Das.Diagnostic Role of Tumour Markers CEA,CA15-3,CA19-9 and CA125 in Lung Cancer[J].Indian J Clin Biochem,2013,28(1):24-29.
[20]刘喆,朱允中,张新勇,等.多项肿瘤标志物在肺癌诊断中的应用[J].北京医学,2002,24(6):384-387.
[21]张洁,陈正福,景欣等.血清CEA和CA125联合检测在肺结核及肺癌诊断中价值探讨[J].航空航天医学杂志,2011,22(11):1334-1335.