肠道微生态促进肠道营养素吸收分子机制及临床意义
摘要
<正>近年来随着基因组学、蛋白质组学及代谢组学等领域不断进展,肠道微生态及其代谢模式改变在营养素代谢吸收方面越来越受到学者的重视。通过肠道微生态促进营养素代谢吸收分子机制研究,有利于更好指导临床合理应用营养支持,增强肠道黏膜屏障保护、改善肠道菌群结构、调节肠道代谢、调控机体内分泌免疫系统、修复组织器官损伤、缓解氧化应激等方面达到治疗疾病的目的。因此,笔者将从肠道微生态生理功能、营养素代谢吸收及临
引文
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[22]Yu HN,Zhu J,Pan WS,et al.Effects of fish oil with a high content of n-3 polyunsaturated fatty acids on mouse gut microbiota.Arch Med Res,2014,45(3):195-202.
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[24]Halmos EP,Gibson PR.Dietary management of IBD-insights and advice.Nat Rev Gastroenterol Hepatol,2015,12(3):133-146.
[25]Jackson AA,Gibson NR,Bundy R,Hounslow A,Millward DJ,Wootton SA.Transfer of(15)N from oral lactose-ureide to lysine in normal adults.Int J Food Sci Nutr,2004,55(6):455-462.
[26]Raj T,Dileep U,Vaz M,et al.Intestinal microbial contribution to metabolic leucine input in adult men.J Nutr,2008,138(11):2217-2221.
[27]Kroemer G,López-Otín C,Madeo F,et al.Carbotoxicity-Noxious Effects of Carbohydrates.Cell,2018,175(3):605-614.
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