摘要
药物化学是药学相关专业的核心课程,具有很强的实践性。实验教学是培养学生动手操作、理论运用及创新能力的重要环节。前药设计可有效改善化合物的类药特征,并避免相关不良反应,是药物分子设计中较为重要也是最为常见的一种改造方法。本教研室针对近几年在实验教学实践遇到的问题,对药化实验教学模式进行了改革,通过开展对乙酰氨基酚前药设计性实验,培养学生创新与科研能力。通过实践提高了学生的文献查阅与实践操作能力,进一步提高学生对药化课程的学习兴趣。
As one of the sole courses of Pharmacy,Medicinal Chemistry relies highly on practice. The practical teaching is the key segment in cultivating students' abilities of handling operation,theory usage and innovation. The prodrug strategy is important in improving the drug-likeness and avoiding side effect. Some reforms in practical education were carried out and the prodrug design of paracetamol was launched,with the aim of cultivating students' innovative and scientific ability. The accomplishment of this experiment raised students' abilities of literature searching and practical operation,and further promoted their interest in Medicinal Chemistry.
引文
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