针刺联合穴位埋线治疗脾胃虚弱型慢性萎缩性胃炎临床观察
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摘要
目的:观察针刺联合穴位埋线治疗脾胃虚弱型慢性萎缩性胃炎的临床疗效。方法:将60例脾胃虚弱型慢性萎缩性胃炎患者分成观察组和对照组,每组30例。对照组采取西医常规治疗,予莫沙必利片,5 mg/次,口服,3次/d必要时加抗HP治疗。观察组予针刺联合穴位埋线治疗。2组疗程均为12周。观察2组治疗前后中医证候积分、病理组织学的变化情况及临床疗效。结果:证候积分治疗前后2组组内比较,差异有统计学意义(P<0.05);治疗后2组组间比较差异也有统计学意义(P<0.05)。治疗后,观察组慢性炎症、胃黏膜腺体萎缩、肠上皮化生、异型增生情况较治疗前明显改善(P<0.05),对照组患者的胃黏膜腺体萎缩、肠上皮化生、异型增生情况较治疗前亦明显改善(P<0.05),且观察组患者胃黏膜萎缩、肠上皮化生改善情况优于对照组(P<0.05)。总有效率观察组为86.7%,对照组为63.3%,2组比较差异有统计学意义(P<0.05)。结论:针刺联合穴位埋线治疗脾胃虚弱型慢性萎缩性胃炎可缓解临床症状,改善胃组织病理表现,提高临床疗效。
Objective: To observe clinical effects of acupuncture joined with catgut implantation at acupoints in treating chronic atrophic gastritis(CAG) of spleen-stomach deficiency pattern. Methods: Sixty patients were randomly allocated to the observation group and the control group, 30 cases each group. The control group used conventional therapy of Western medicine and took mosapride orally, 5 mg each time, tral administration, three times each day, performed anti-Hp therapy when necessary. The observation group were treated by acupuncture combined with catgut implantation at acupoints. The course was 12 weeks. Syndrome scores, pathological tissues and clinical effects of both groups were observed before and after treating. Results: The difference had statistical meaning in the comparisons of syndrome scores within two groups before and after treating(P< 0.05); the difference was statistically significant in the comparisons between both groups after treating(P < 0.05). After treating, chronic inflammation, gastric mucosa gland atrophy, intestinal metaplasia and dysplasia of the observation group improved compared with before treating notably(P< 0.05), the conditions of the control group improved than before treating remarkably(P< 0.05), the improvements of the observation group were superior to these of the control group(P<0.05). Total effective rate of the observation group was 86.7%, higher than 63.3% of the control group, and the difference showed statistical meaning(P < 0.05). Conclusion: Acupuncture joined with catgut implantation at acupoints could relieve clinical symptoms, improve clinical manifestations of stomach tissue and raise clinical effects in treating CAG of spleen-stomach deficiency pattern.
Objective: To observe clinical effects of acupuncture joined with catgut implantation at acupoints in treating chronic atrophic gastritis(CAG) of spleen-stomach deficiency pattern. Methods: Sixty patients were randomly allocated to the observation group and the control group, 30 cases each group. The control group used conventional therapy of Western medicine and took mosapride orally, 5 mg each time, tral administration, three times each day, performed anti-Hp therapy when necessary. The observation group were treated by acupuncture combined with catgut implantation at acupoints. The course was 12 weeks. Syndrome scores, pathological tissues and clinical effects of both groups were observed before and after treating. Results: The difference had statistical meaning in the comparisons of syndrome scores within two groups before and after treating(P< 0.05); the difference was statistically significant in the comparisons between both groups after treating(P < 0.05). After treating, chronic inflammation, gastric mucosa gland atrophy, intestinal metaplasia and dysplasia of the observation group improved compared with before treating notably(P< 0.05), the conditions of the control group improved than before treating remarkably(P< 0.05), the improvements of the observation group were superior to these of the control group(P<0.05). Total effective rate of the observation group was 86.7%, higher than 63.3% of the control group, and the difference showed statistical meaning(P < 0.05). Conclusion: Acupuncture joined with catgut implantation at acupoints could relieve clinical symptoms, improve clinical manifestations of stomach tissue and raise clinical effects in treating CAG of spleen-stomach deficiency pattern.
引文
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[10]田超.“俞募配穴通腑法”治疗反胃80例疗效观察[J].按摩与导引,2009,8(25):20-22.
[11]陈婷,余小夏,刘旭光.针刺胃经穴位对胃功能影响的研究与思考[J].针灸临床杂志,2009,25(3):49-51.
[12]贺大璞,莫靓,游咏,等.三种缝合材料对兔气管吻合口愈合质量的影响[J].中国组织工程研究与临床康复,2007,11(40):8034-8037.
[13]张红石,王富春.合募配穴与俞原配穴在脏腑辨证中的应用[J].中国针灸,2006,26(5):379-380.
[2]丁成华,李晶晶,方芳,等.慢性萎缩性胃炎中医病机与证候分布规律研究[J].中华中医药杂志,2011,26(3):582-586.
[3]朱海涛.穴位埋线治疗慢性萎缩性胃炎疗效观察[J].上海针灸杂志,2008,27(12):11-12.
[4]潘文斌,梁霞,王丽荣,等.四合汤合穴位埋线治疗慢性萎缩性胃炎伴肠上皮化生60例[J].中国中医药现代远程教育,2011,9(16):36-37.
[5]牛桦,李涛,何晓华,等.穴位埋线治疗慢性萎缩性胃炎的临床观察[J].宁夏医学杂志,2012,34(11):1178-1180.
[6]李国徽,陈佳,陈凌,等.穴位埋线治疗慢性萎缩性胃炎65例[J].陕西中医,2014,35(1):73-74.
[7]房静远,刘文忠.中国慢性胃炎共识意见[J].中华消化杂志,2013,33(1):5-15.
[8]郑筱萸.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002:125-126.
[9]张晓倩,鲁重美.幽门螺杆菌、慢性萎缩性胃炎与胃癌[J].临床消化病杂志,2016,28(3):192-195.
[10]田超.“俞募配穴通腑法”治疗反胃80例疗效观察[J].按摩与导引,2009,8(25):20-22.
[11]陈婷,余小夏,刘旭光.针刺胃经穴位对胃功能影响的研究与思考[J].针灸临床杂志,2009,25(3):49-51.
[12]贺大璞,莫靓,游咏,等.三种缝合材料对兔气管吻合口愈合质量的影响[J].中国组织工程研究与临床康复,2007,11(40):8034-8037.
[13]张红石,王富春.合募配穴与俞原配穴在脏腑辨证中的应用[J].中国针灸,2006,26(5):379-380.