Profile of Dr. Jie Qiao
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摘要
<正>Dr. Jie Qiao is a reproductive medicine physician and a biological scientist. For more than 30 years, she has devoted herself to the molecular mechanism study of human gamete/embryo development, diagnosis and treatment of difficult infertility, especially the translation from basic research to clinical application. She studied Clinical Medicine and Obstetrics&Gynecology in Beijing Medical University, now
引文
Dang,Y.,Yan,L.,Hu,B.,Fan,X.,Ren,Y.,Li,R.,Lian,Y.,Yan,J.,Li,Q.,Zhang,Y.,et al.(2016).Tracing the expression of circular RNAs in human pre-implantation embryos.Genome Biol 17,130.
Gao,S.,Yan,L.,Wang,R.,Li,J.,Yong,J.,Zhou,X.,Wei,Y.,Wu,X.,Wang,X.,Fan,X.,et al.(2018).Tracing the temporal-spatial transcriptome landscapes of the human fetal digestive tract using single-cell RNA-sequencing.Nat Cell Biol 20,721-734.
Guo,F.,Yan,L.,Guo,H.,Li,L.,Hu,B.,Zhao,Y.,Yong,J.,Hu,Y.,Wang,X.,Wei,Y.,et al.(2015).The transcriptome and DNA methylome landscapes of human primordial germ cells.Cell 161,1437-1452.
Guo,H.,Hu,B.,Yan,L.,Yong,J.,Wu,Y.,Gao,Y.,Guo,F.,Hou,Y.,Fan,X.,Dong,J.,et al.(2017).DNA methylation and chromatin accessibility profiling of mouse and human fetal germ cells.Cell Res27,165-183.
Guo,H.,Zhu,P.,Yan,L.,Li,R.,Hu,B.,Lian,Y.,Yan,J.,Ren,X.,Lin,S.,Li,J.,et al.(2014).The DNA methylation landscape of human early embryos.Nature 511,606-610.
Hou,Y.,Fan,W.,Yan,L.,Li,R.,Lian,Y.,Huang,J.,Li,J.,Xu,L.,Tang,F.,Xie,X.S.,et al.(2013).Genome analyses of single human oocytes.Cell155,1492-1506.
Li,L.,Dong,J.,Yan,L.,Yong,J.,Liu,X.,Hu,Y.,Fan,X.,Wu,X.,Guo,H.,Wang,X.,et al.(2017).Single-cell RNA-seq analysis maps development of human germline cells and gonadal niche interactions.Cell Stem Cell 20,858-873.e4.
Li,L.,Guo,F.,Gao,Y.,Ren,Y.,Yuan,P.,Yan,L.,Li,R.,Lian,Y.,Li,J.,Hu,B.,et al.(2018).Single-cell multi-omics sequencing of human early embryos.Nat Cell Biol 20,847-858.
Li,R.,Yu,G.,Yang,D.,Li,S.,Lu,S.,Wu,X.,Wei,Z.,Song,X.,Wang,X.,Fu,S.,et al.(2014).Prevalence and predictors of metabolic abnormalities in Chinese women with PCOS:a cross-sectional study.BMC Endocr Disord 14,76.
Li,R.,Zhang,Q.,Yang,D.,Li,S.,Lu,S.,Wu,X.,Wei,Z.,Song,X.,Wang,X.,Fu,S.,et al.(2013).Prevalence of polycystic ovary syndrome in women in China:a large community-based study.Human Reprod 28,2562-2569.
Ren,Y.,Zhi,X.,Zhu,X.,Huang,J.,Lian,Y.,Li,R.,Jin,H.,Zhang,Y.,Zhang,W.,Nie,Y.,et al.(2016).Clinical applications of MARSALAfor preimplantation genetic diagnosis of spinal muscular atrophy.JGenets Genomics 43,541-547.
Wang,H.,Gao,H.,Chi,H.,Zeng,L.,Xiao,W.,Wang,Y.,Li,R.,Liu,P.,Wang,C.,Tian,Q.,et al.(2017).Effect of levothyroxine on miscarriage among women with normal thyroid function and thyroid autoimmunity undergoing in vitro fertilization and embryo transfer.JAMA 318,2190-2198.
Yan,L.,Yang,M.,Guo,H.,Yang,L.,Wu,J.,Li,R.,Liu,P.,Lian,Y.,Zheng,X.,Yan,J.,et al.(2013).Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells.Nat Struct Mol Biol 20,1131-1139.
Yan,L.,Huang,L.,Xu,L.,Huang,J.,Ma,F.,Zhu,X.,Tang,Y.,Liu,M.,Lian,Y.,Liu,P.,et al.(2015).Live births after simultaneous avoidance of monogenic diseases and chromosome abnormality by nextgeneration sequencing with linkage analyses.Proc Natl Acad Sci USA 112,15964-15969.
Yan,Z.,Wang,Y.,Nie,Y.,Zhi,X.,Zhu,X.,Qin,M.,Guan,S.,Ren,Y.,Kuo,Y.,Chang,D.,et al.(2018).Identifying normal embryos from reciprocal translocation carriers by whole chromosome haplotyping.JGenets Genomics 45,505-508.
Yang,Q.,Zhao,Y.,Qiu,X.,Zhang,C.,Li,R.,and Qiao,J.(2015).Association of serum levels of typical organic pollutants with polycystic ovary syndrome(PCOS):a case-control study.Hum Reprod 30,1964-1973.
Zhang,C.,Zhao,Y.,Li,R.,Yu,Y.,Yan,L.,Li,L.,Liu,N.,Liu,P.,and Qiao,J.(2014).Metabolic heterogeneity of follicular amino acids in polycystic ovary syndrome is affected by obesity and related to pregnancy outcome.BMC Pregnancy Childbirth 14,11.
Zhu,P.,Guo,H.,Ren,Y.,Hou,Y.,Dong,J.,Li,R.,Lian,Y.,Fan,X.,Hu,B.,Gao,Y.,et al.(2018).Single-cell DNA methylome sequencing of human preimplantation embryos.Nat Genet 50,12-19.
Gao,S.,Yan,L.,Wang,R.,Li,J.,Yong,J.,Zhou,X.,Wei,Y.,Wu,X.,Wang,X.,Fan,X.,et al.(2018).Tracing the temporal-spatial transcriptome landscapes of the human fetal digestive tract using single-cell RNA-sequencing.Nat Cell Biol 20,721-734.
Guo,F.,Yan,L.,Guo,H.,Li,L.,Hu,B.,Zhao,Y.,Yong,J.,Hu,Y.,Wang,X.,Wei,Y.,et al.(2015).The transcriptome and DNA methylome landscapes of human primordial germ cells.Cell 161,1437-1452.
Guo,H.,Hu,B.,Yan,L.,Yong,J.,Wu,Y.,Gao,Y.,Guo,F.,Hou,Y.,Fan,X.,Dong,J.,et al.(2017).DNA methylation and chromatin accessibility profiling of mouse and human fetal germ cells.Cell Res27,165-183.
Guo,H.,Zhu,P.,Yan,L.,Li,R.,Hu,B.,Lian,Y.,Yan,J.,Ren,X.,Lin,S.,Li,J.,et al.(2014).The DNA methylation landscape of human early embryos.Nature 511,606-610.
Hou,Y.,Fan,W.,Yan,L.,Li,R.,Lian,Y.,Huang,J.,Li,J.,Xu,L.,Tang,F.,Xie,X.S.,et al.(2013).Genome analyses of single human oocytes.Cell155,1492-1506.
Li,L.,Dong,J.,Yan,L.,Yong,J.,Liu,X.,Hu,Y.,Fan,X.,Wu,X.,Guo,H.,Wang,X.,et al.(2017).Single-cell RNA-seq analysis maps development of human germline cells and gonadal niche interactions.Cell Stem Cell 20,858-873.e4.
Li,L.,Guo,F.,Gao,Y.,Ren,Y.,Yuan,P.,Yan,L.,Li,R.,Lian,Y.,Li,J.,Hu,B.,et al.(2018).Single-cell multi-omics sequencing of human early embryos.Nat Cell Biol 20,847-858.
Li,R.,Yu,G.,Yang,D.,Li,S.,Lu,S.,Wu,X.,Wei,Z.,Song,X.,Wang,X.,Fu,S.,et al.(2014).Prevalence and predictors of metabolic abnormalities in Chinese women with PCOS:a cross-sectional study.BMC Endocr Disord 14,76.
Li,R.,Zhang,Q.,Yang,D.,Li,S.,Lu,S.,Wu,X.,Wei,Z.,Song,X.,Wang,X.,Fu,S.,et al.(2013).Prevalence of polycystic ovary syndrome in women in China:a large community-based study.Human Reprod 28,2562-2569.
Ren,Y.,Zhi,X.,Zhu,X.,Huang,J.,Lian,Y.,Li,R.,Jin,H.,Zhang,Y.,Zhang,W.,Nie,Y.,et al.(2016).Clinical applications of MARSALAfor preimplantation genetic diagnosis of spinal muscular atrophy.JGenets Genomics 43,541-547.
Wang,H.,Gao,H.,Chi,H.,Zeng,L.,Xiao,W.,Wang,Y.,Li,R.,Liu,P.,Wang,C.,Tian,Q.,et al.(2017).Effect of levothyroxine on miscarriage among women with normal thyroid function and thyroid autoimmunity undergoing in vitro fertilization and embryo transfer.JAMA 318,2190-2198.
Yan,L.,Yang,M.,Guo,H.,Yang,L.,Wu,J.,Li,R.,Liu,P.,Lian,Y.,Zheng,X.,Yan,J.,et al.(2013).Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells.Nat Struct Mol Biol 20,1131-1139.
Yan,L.,Huang,L.,Xu,L.,Huang,J.,Ma,F.,Zhu,X.,Tang,Y.,Liu,M.,Lian,Y.,Liu,P.,et al.(2015).Live births after simultaneous avoidance of monogenic diseases and chromosome abnormality by nextgeneration sequencing with linkage analyses.Proc Natl Acad Sci USA 112,15964-15969.
Yan,Z.,Wang,Y.,Nie,Y.,Zhi,X.,Zhu,X.,Qin,M.,Guan,S.,Ren,Y.,Kuo,Y.,Chang,D.,et al.(2018).Identifying normal embryos from reciprocal translocation carriers by whole chromosome haplotyping.JGenets Genomics 45,505-508.
Yang,Q.,Zhao,Y.,Qiu,X.,Zhang,C.,Li,R.,and Qiao,J.(2015).Association of serum levels of typical organic pollutants with polycystic ovary syndrome(PCOS):a case-control study.Hum Reprod 30,1964-1973.
Zhang,C.,Zhao,Y.,Li,R.,Yu,Y.,Yan,L.,Li,L.,Liu,N.,Liu,P.,and Qiao,J.(2014).Metabolic heterogeneity of follicular amino acids in polycystic ovary syndrome is affected by obesity and related to pregnancy outcome.BMC Pregnancy Childbirth 14,11.
Zhu,P.,Guo,H.,Ren,Y.,Hou,Y.,Dong,J.,Li,R.,Lian,Y.,Fan,X.,Hu,B.,Gao,Y.,et al.(2018).Single-cell DNA methylome sequencing of human preimplantation embryos.Nat Genet 50,12-19.