ICL术后应用溴芬酸钠滴眼液安全性的临床观察
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摘要
目的探讨溴芬酸钠滴眼液在ICL术后常规应用的临床效果。方法收集2014年1月—2015年3月的80例ICL手术患者的临床资料,按照数字表法将患者分为观察组和对照组。每组各40例(80只眼),观察组患者采用溴芬酸钠滴眼液,对照组患者用妥布霉素地塞米松滴眼液作为ICL术后治疗用药,比较两组患者用药后的临床效果和常见并发症。结果术后1个月时,两组患者在治愈率方面比较,差异无统计学意义(χ2=1.01,P> 0.05)。结膜炎发生率方面比较,差异无统计学意义(χ2=3.06,P> 0.05),眼部刺激感发生率方面比较,差异无统计学意义(χ2=1.03,P> 0.05),角膜糜烂发生率方面比较,差异无统计学意义(χ2=0.34,P> 0.05),在高眼症发生率比较,差异无统计学意义(χ2=2.03,P> 0.05)。结论 ICL术后可使用溴芬酸钠滴眼液替代或减少妥布霉素地塞米松滴眼液的使用量。
Objective To discuss the effect of bromfenac sodium eye drop after ICL surgery. Methods Clinical data of 80 ICL patients from January 2014 to March 2015 were collected and divided into two groups with 40 patients(80 eyes) in each group. The experimental gruop was treated with bromfenac sodium eye drop after ICL surgery. The congtrol group was treated with tobramycin dexamethasone eye drops instead. The effect and complications were compared. Results There was no statistics significance in cure rate between the two groups at one month(χ2=1.01, P > 0.05). There was no statistics significance in the incidence of conjunctivitis between the two groups at one month(χ2=3.06, P > 0.05). There was no statistics significance in incidence of ocular irritation between the two groups at one month(χ2=1.03, P > 0.05). There was no statistics significance in corneal erosion between the two groups at one month(χ2=0.34, P > 0.05). There was no statistics significance in OHT between the two groups at one month(χ2=2.03, P > 0.05). Conclusion Bromfenac sodium eye drop could replace or reduce the tobramycin dexamethasone eye drops after ICL surgery.
Objective To discuss the effect of bromfenac sodium eye drop after ICL surgery. Methods Clinical data of 80 ICL patients from January 2014 to March 2015 were collected and divided into two groups with 40 patients(80 eyes) in each group. The experimental gruop was treated with bromfenac sodium eye drop after ICL surgery. The congtrol group was treated with tobramycin dexamethasone eye drops instead. The effect and complications were compared. Results There was no statistics significance in cure rate between the two groups at one month(χ2=1.01, P > 0.05). There was no statistics significance in the incidence of conjunctivitis between the two groups at one month(χ2=3.06, P > 0.05). There was no statistics significance in incidence of ocular irritation between the two groups at one month(χ2=1.03, P > 0.05). There was no statistics significance in corneal erosion between the two groups at one month(χ2=0.34, P > 0.05). There was no statistics significance in OHT between the two groups at one month(χ2=2.03, P > 0.05). Conclusion Bromfenac sodium eye drop could replace or reduce the tobramycin dexamethasone eye drops after ICL surgery.
引文
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[6]李阳,廖荣丰.后房型有晶状体眼人工晶状体植入联合角膜松解矫正高度近视合并散光的疗效观察[J].临床眼科杂志,2016,24(4):296-299.
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[8]Rovere G,Nadal-Nicol S FM,Sobrado-Calvo P,et al. Topical treatment with bromfenac reduces retinal gliosis and inflammation after optic nerve crush[J]. Invest Ophthalmol Vis Sci,2016,57(14):6098-6106.
[9]李玉雯,吴保华,吴鹏程,等.探讨矫正高度近视的两种眼内屈光手术的临床效果[J].中国医学创新,2014,7(12):74-76.
[10]孙成淑,邓应平.中央孔型有晶状体眼后房型人工晶状体矫正高度近视性屈光不正的疗效[J].国际眼科杂志,2018,18(5):963-967.
[11]范华,季鹏,祖培培,等.新型后房型有晶状体眼IOL植入术治疗伴有低度散光的高度近视[J].国际眼科杂志,2018,18(7):1346-1348.
[12]杨夏玲,金奇芳,张倩,等.有晶状体眼后房屈光晶状体植入术治疗超高度近视的临床观察[J].江西医药,2014,61(12):1342-1345.
[2]胡锡彬,何建中,邱艳飞,等.有晶状体眼后房型人工晶状体植入术矫正高度近视的临床观察[J].临床医药实践,2017,26(3):189-192.
[3]李琴,张少维,黄毅.有晶状体眼后房型人工晶状体植入矫正高度近视的临床观察[J].国际眼科杂志,2016,16(9):1709-1711.
[4]唐磊,廖荣丰.中央孔型有晶状体眼后房型人工晶体矫正高度近视的临床研究[J].安徽医科大学学报,2017,52(6):915-920.
[5]胡盼,杨玉琼,黄菊.有晶状体眼后房型人工晶状体植入术治疗高度近视的围手术期护理[J].护理实践与研究,2015,12(4):78-79.
[6]李阳,廖荣丰.后房型有晶状体眼人工晶状体植入联合角膜松解矫正高度近视合并散光的疗效观察[J].临床眼科杂志,2016,24(4):296-299.
[7]Sheppard JD. Topical bromfenac for prevention and treatment of cystoid macular edema following cataract surgery:a review[J]. Clin Ophthalmol,2016,25(10):2099-2111.
[8]Rovere G,Nadal-Nicol S FM,Sobrado-Calvo P,et al. Topical treatment with bromfenac reduces retinal gliosis and inflammation after optic nerve crush[J]. Invest Ophthalmol Vis Sci,2016,57(14):6098-6106.
[9]李玉雯,吴保华,吴鹏程,等.探讨矫正高度近视的两种眼内屈光手术的临床效果[J].中国医学创新,2014,7(12):74-76.
[10]孙成淑,邓应平.中央孔型有晶状体眼后房型人工晶状体矫正高度近视性屈光不正的疗效[J].国际眼科杂志,2018,18(5):963-967.
[11]范华,季鹏,祖培培,等.新型后房型有晶状体眼IOL植入术治疗伴有低度散光的高度近视[J].国际眼科杂志,2018,18(7):1346-1348.
[12]杨夏玲,金奇芳,张倩,等.有晶状体眼后房屈光晶状体植入术治疗超高度近视的临床观察[J].江西医药,2014,61(12):1342-1345.