奥曲肽微量注射泵持续注射治疗急性胰腺炎
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摘要
目的探究对急性胰腺炎患者进行奥曲肽微量注射泵持续注射治疗的临床效果。方法选取2015年8月—2018年8月医院收治的85例急性胰腺炎患者作为研究对象,将其随机分为两组。研究组(43例)行奥曲肽微量注射泵持续注射治疗;对照组(42例)行奥曲肽皮下注射治疗。观察、比较两组患者的具体治疗效果。结果研究组患者的腹痛消失情况、血淀粉酶恢复情况、进食恢复情况均优于对照组,差异均具有统计学意义(P <0.05);研究组患者的住院时间短于对照组,差异具有统计学意义(P <0.05);研究组患者的总有效率(97.67%)高于对照组(85.71%),差异具有统计学意义(P <0.05);研究组患者的腹泻发生率(4.65%)低于对照组(14.29%),差异具有统计学意义(P <0.05)。结论对急性胰腺炎患者行奥曲肽微量注射泵持续注射治疗,既可显著增强临床疗效,由可减少不良反应,提高临床治疗安全性。
Objective To explore the clinical effect of continuous octreotide microinjection pump in the treatment of acute pancreatitis. Methods 85 patients with acute pancreatitis admitted to our hospital from August 2015 to August 2018 were selected as the study subjects. They were randomly divided into two groups. The study group(43 cases) received continuous injection of octreotide by microinjection pump. The control group(42 cases)received subcutaneous injection of octreotide. To observe and compare the specific therapeutic effect of two groups of patients. Results The abdominal pain disappearance, blood amylase recovery and food recovery in the study group were better than those in the control group, and the difference was statistically significant(P < 0.05). The hospitalization time of the study group was shorter than that of the control group, and the difference was statistically significant(P < 0.05). The total effective rate of the study group(97.67%) was higher than that of the control group(85.71%). The difference was statistically significant(P < 0.05). The incidence of diarrhea in the study group(4.65%) was lower than that in the control group(14.29%). The difference was statistically significant(P < 0.05). Conclusion Continuous octreotide microinjection pump for the treatment of acute pancreatitis can significantly enhance the clinical efficacy, reduce adverse reactions and improve the safety of clinical treatment, which is worthy of promotion.
Objective To explore the clinical effect of continuous octreotide microinjection pump in the treatment of acute pancreatitis. Methods 85 patients with acute pancreatitis admitted to our hospital from August 2015 to August 2018 were selected as the study subjects. They were randomly divided into two groups. The study group(43 cases) received continuous injection of octreotide by microinjection pump. The control group(42 cases)received subcutaneous injection of octreotide. To observe and compare the specific therapeutic effect of two groups of patients. Results The abdominal pain disappearance, blood amylase recovery and food recovery in the study group were better than those in the control group, and the difference was statistically significant(P < 0.05). The hospitalization time of the study group was shorter than that of the control group, and the difference was statistically significant(P < 0.05). The total effective rate of the study group(97.67%) was higher than that of the control group(85.71%). The difference was statistically significant(P < 0.05). The incidence of diarrhea in the study group(4.65%) was lower than that in the control group(14.29%). The difference was statistically significant(P < 0.05). Conclusion Continuous octreotide microinjection pump for the treatment of acute pancreatitis can significantly enhance the clinical efficacy, reduce adverse reactions and improve the safety of clinical treatment, which is worthy of promotion.
引文
[1]蔡少薇,张刚庆,许鸣.泵注与静滴奥曲肽治疗77例急性胰腺炎的随机对照研究[J].胃肠病学和肝病学杂志,2014,23(12):1468-1470.
[2]宋辉,刘金煌,杨志伟.奥曲肽不同应用方式治疗胰腺炎75例疗效分析[J].临床医学,2016,36(2):76-77.
[3]黄志明.奥曲肽不同应用方式治疗胰腺炎患者90例疗效研究[J].中国医药科学,2016,6(21):90-92.
[4]樊启源,陈红霞.对胰腺炎行奥曲肽不同应用方式治疗的效果对比探析[J].当代医学,2016,22(17):141-142.
[5]熊伟.奥曲肽不同应用方式治疗130例胰腺炎患者的临床效果分析[J].中外医学研究,2016,14(17):117-118.
[6]莫有海.奥曲肽不同给药方式在胰腺炎患者中的应用及疗效对比观察[J].中国社区医师,2015,31(12):54-55.
[7]朱文通.对比奥曲肽的不同给药方式治疗胰腺炎的效果[J].中国卫生标准管理,2018,9(14):80-82.
[8]崔宝月.奥曲肽不同给药方法治疗急性胰腺炎的临床效果[J].北方药学,2018,15(10):103-104.
[9]王艳玲,何建军.奥曲肽不同应用方式治疗胰腺炎的临床效果分析[J].中外医疗,2015,34(26):127-128.
[10]张卫静.急性水肿型胰腺炎采用奥曲肽治疗的临床探讨[J].中外医疗,2017,36(9):135-137.
[11]刘晓娟.奥曲肽与乌司他丁联用治疗胰腺炎分析[J].中国社区医师,2016,32(23):32-33.
[12]郭秀花.奥曲肽联合乳果糖灌肠治疗急性胰腺炎的效果观察[J].中国基层医药,2018,25(3):387-389.
[2]宋辉,刘金煌,杨志伟.奥曲肽不同应用方式治疗胰腺炎75例疗效分析[J].临床医学,2016,36(2):76-77.
[3]黄志明.奥曲肽不同应用方式治疗胰腺炎患者90例疗效研究[J].中国医药科学,2016,6(21):90-92.
[4]樊启源,陈红霞.对胰腺炎行奥曲肽不同应用方式治疗的效果对比探析[J].当代医学,2016,22(17):141-142.
[5]熊伟.奥曲肽不同应用方式治疗130例胰腺炎患者的临床效果分析[J].中外医学研究,2016,14(17):117-118.
[6]莫有海.奥曲肽不同给药方式在胰腺炎患者中的应用及疗效对比观察[J].中国社区医师,2015,31(12):54-55.
[7]朱文通.对比奥曲肽的不同给药方式治疗胰腺炎的效果[J].中国卫生标准管理,2018,9(14):80-82.
[8]崔宝月.奥曲肽不同给药方法治疗急性胰腺炎的临床效果[J].北方药学,2018,15(10):103-104.
[9]王艳玲,何建军.奥曲肽不同应用方式治疗胰腺炎的临床效果分析[J].中外医疗,2015,34(26):127-128.
[10]张卫静.急性水肿型胰腺炎采用奥曲肽治疗的临床探讨[J].中外医疗,2017,36(9):135-137.
[11]刘晓娟.奥曲肽与乌司他丁联用治疗胰腺炎分析[J].中国社区医师,2016,32(23):32-33.
[12]郭秀花.奥曲肽联合乳果糖灌肠治疗急性胰腺炎的效果观察[J].中国基层医药,2018,25(3):387-389.