电刺激强度在诊断糖尿病神经病变中的价值
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摘要
目的 探究电刺激强度在诊断糖尿病神经病变中的价值。方法 选择健康体检者50例健康人作为对照组和糖尿病周围神经病变50例作为观察组,检测两组下肢胫神经运动电位波幅、腓肠神经感觉电位波幅以及引出最佳胫神经动作电位波形的刺激强度(mA)和最佳腓肠神经动作电位波形的刺激强度(mA),通过上述指标观察分析胫神经运动电位波幅及腓肠神经感觉电位波幅,以及引出最佳动作电位刺激强度。结果 观察组胫神经运动电位、腓肠神经感觉电位波幅较对照组明显降低(P<0.05),且观察组需要引出最佳胫神经运动电位波形与腓肠神经感觉电位波形的刺激强度显著高于对照组。结论 糖尿病神经病变患者引出最佳动作电位波形的刺激强度明显增高,在诊断糖尿病神经病变中具有重要价值。
Objective To explore the value of electrical stimulation intensity in diagnosis of diabetic neuropathy. Methods Fifty healthy subjects in physical health examination were selected as a control group and 50 diabetic peripheral neuropathy patients as an observation group. The tibial nerve motor potential amplitude of lower limb, the sural nerve sensory potential amplitude, the stimulus intensity (mA) leading to the best tibial nerve action potential waveform and stimulus intensity (mA) leading to the best sural nerve action potential waveform were measured in patients' lower limbs of both groups. The tibial nerve motor potential amplitude, sural nerve sensory potential amplitude and the best stimulation intensity leading to the best action potential waveform were observed and analyzed. Results The amplitudes of tibial motor potential and sural nerve sensory potential in the observation group were significantly lower than those in the control group (P<0.05), furthermore, the needed stimulation intensities leading to the best tibial motor potential and sural nerve sensory potential waveforms in the observation group were significantly higher than those in the control group. Conclusion The stimulation intensity leading to the best action potential waveform in patients with diabetic neuropathy is significantly increased, which is of great value in diagnosis of diabetic neuropathy.
Objective To explore the value of electrical stimulation intensity in diagnosis of diabetic neuropathy. Methods Fifty healthy subjects in physical health examination were selected as a control group and 50 diabetic peripheral neuropathy patients as an observation group. The tibial nerve motor potential amplitude of lower limb, the sural nerve sensory potential amplitude, the stimulus intensity (mA) leading to the best tibial nerve action potential waveform and stimulus intensity (mA) leading to the best sural nerve action potential waveform were measured in patients' lower limbs of both groups. The tibial nerve motor potential amplitude, sural nerve sensory potential amplitude and the best stimulation intensity leading to the best action potential waveform were observed and analyzed. Results The amplitudes of tibial motor potential and sural nerve sensory potential in the observation group were significantly lower than those in the control group (P<0.05), furthermore, the needed stimulation intensities leading to the best tibial motor potential and sural nerve sensory potential waveforms in the observation group were significantly higher than those in the control group. Conclusion The stimulation intensity leading to the best action potential waveform in patients with diabetic neuropathy is significantly increased, which is of great value in diagnosis of diabetic neuropathy.
引文
[1] 符黄德,舒清峰,唐乾利,等.MEBT/MEBO对Wagner Ⅱ级糖尿病足溃疡病人28 d创面愈合率及周围神经病变的影响研究[J].右江民族医学院学报,2018,40(3):209-212.
[2] 郭妮.抗氧化应激在糖尿病周围神经病变治疗中的作用研究[ J].右江民族医学院学报,2013,35(5):678-680.
[3] 戚艳艳.神经电生理指标与糖尿病周围神经病变病情分级的相关性分析[J].河北医科大学学报,2019,40(2):161-164,168.
[4] 中国医师协会内分泌代谢科医师分会.糖尿病周围神经病变诊疗规范(征求意见稿)[J].中国糖尿病杂志,2009,17(8):638-640.
[5] 中华医学会神经病学分会,中华医学会神经病学分会肌肉病学组,中华医学会神经病学分会肌电图与临床神经生理学组.肌电图规范化检测与临床应用共识修订版[J].中华神经科杂志,2015,48(11):950-964.
[6] 孙庆权,赵蒙,殷宏宇,等.比较分析F波检测在糖尿病周围神经病变电生理检查中的价值[J].中国医师进修杂志,2017,40(12):1095-1099.
[7] 邹伟伟,刘鉴,王根保,等.舒芬太尼对糖尿病周围神经病变术后镇痛效应的影响[J].右江民族医学院学报,2015,37(3):380-383.
[8] 尹毅霞,李凤玲,王民登,等.氢化麦角碱治疗糖尿病周围神经病变效果观察[J].右江民族医学院学报,2001,23(4):530-531.
[9] 汪仁斌,杨兆军,孙少杰,等.F波和H反射对糖尿病近端神经病的诊断作用[J].中日友好医院学报,2013,27(3):135-137.
[10] 尚媛媛,陈香葵.糖尿病性周围神经病患者的神经电生理分析[J].癫痫与神经电生理学杂志,2018,27(6):346-348.
[11] Wiessman MP,Liberty IF,Segev RW,et al.Clinical characteristics and survival of patients with diabetes mellitus following non-traumatic lower extremity amputation[J].Isr Med Assoc J,2015,17(3):145-149.
[12] Erbas O,Oltulu F,Ylmaz M,et al.Neuroprotective effects of chronic administration of levetiracetam in a rat model of diabetic neuropathy[J].Diabetes Res Clin Pract,2016,114:106-116.
[13] Morales-Vidal S,Morgan C,McCoyd M,et al.Diabetic peripheral neuropathy and the management of diabetic peripheral neuropathic pain[J].Postgrad Med,2012,124(4):145-153.
[14] Deshmukh V,Deshmukh C.Achieving good glycaemic control effective use of self monitoring of blood glucose (SMBG) [J].J Indian Med Assoc,2012,110(3):161-163.
[15] 张继泽,潘颖华,代淑华,等.神经电生理检查在糖尿病周围神经病变中的应用[J].黑龙江医药科学,2018,41(3):118,120.
[16] 宋建敏,许瑾瑾,丁玲,等.神经传导检测对早期诊断1型糖尿病儿童周围神经病变的敏感性[J].中华糖尿病杂志,2018,10(11):718-723.
[17] 王玉珍,许樟荣.震动感觉阈值检查在糖尿病神经病变诊断中的应用[J].国际内分泌代谢杂志,2007,27(1):47-49.
[2] 郭妮.抗氧化应激在糖尿病周围神经病变治疗中的作用研究[ J].右江民族医学院学报,2013,35(5):678-680.
[3] 戚艳艳.神经电生理指标与糖尿病周围神经病变病情分级的相关性分析[J].河北医科大学学报,2019,40(2):161-164,168.
[4] 中国医师协会内分泌代谢科医师分会.糖尿病周围神经病变诊疗规范(征求意见稿)[J].中国糖尿病杂志,2009,17(8):638-640.
[5] 中华医学会神经病学分会,中华医学会神经病学分会肌肉病学组,中华医学会神经病学分会肌电图与临床神经生理学组.肌电图规范化检测与临床应用共识修订版[J].中华神经科杂志,2015,48(11):950-964.
[6] 孙庆权,赵蒙,殷宏宇,等.比较分析F波检测在糖尿病周围神经病变电生理检查中的价值[J].中国医师进修杂志,2017,40(12):1095-1099.
[7] 邹伟伟,刘鉴,王根保,等.舒芬太尼对糖尿病周围神经病变术后镇痛效应的影响[J].右江民族医学院学报,2015,37(3):380-383.
[8] 尹毅霞,李凤玲,王民登,等.氢化麦角碱治疗糖尿病周围神经病变效果观察[J].右江民族医学院学报,2001,23(4):530-531.
[9] 汪仁斌,杨兆军,孙少杰,等.F波和H反射对糖尿病近端神经病的诊断作用[J].中日友好医院学报,2013,27(3):135-137.
[10] 尚媛媛,陈香葵.糖尿病性周围神经病患者的神经电生理分析[J].癫痫与神经电生理学杂志,2018,27(6):346-348.
[11] Wiessman MP,Liberty IF,Segev RW,et al.Clinical characteristics and survival of patients with diabetes mellitus following non-traumatic lower extremity amputation[J].Isr Med Assoc J,2015,17(3):145-149.
[12] Erbas O,Oltulu F,Ylmaz M,et al.Neuroprotective effects of chronic administration of levetiracetam in a rat model of diabetic neuropathy[J].Diabetes Res Clin Pract,2016,114:106-116.
[13] Morales-Vidal S,Morgan C,McCoyd M,et al.Diabetic peripheral neuropathy and the management of diabetic peripheral neuropathic pain[J].Postgrad Med,2012,124(4):145-153.
[14] Deshmukh V,Deshmukh C.Achieving good glycaemic control effective use of self monitoring of blood glucose (SMBG) [J].J Indian Med Assoc,2012,110(3):161-163.
[15] 张继泽,潘颖华,代淑华,等.神经电生理检查在糖尿病周围神经病变中的应用[J].黑龙江医药科学,2018,41(3):118,120.
[16] 宋建敏,许瑾瑾,丁玲,等.神经传导检测对早期诊断1型糖尿病儿童周围神经病变的敏感性[J].中华糖尿病杂志,2018,10(11):718-723.
[17] 王玉珍,许樟荣.震动感觉阈值检查在糖尿病神经病变诊断中的应用[J].国际内分泌代谢杂志,2007,27(1):47-49.