头孢他啶结合多索茶碱对慢性阻塞性肺气肿患者疗效的影响观察
|
摘要
目的探讨头孢他啶结合多索茶碱对慢性阻塞性肺气肿患者疗效的影响观察。方法选取2017年7月—2018年7月进入四川省凉山州第一人民医院进行治疗的慢性肺气肿患者96例作为研究对象,按照治疗的方法随机将其随机分为观察组与对照组,各48例。其中对照组使用常规治疗方案进行治疗,观察组患者采用头孢他啶结合多索茶碱进行治疗,比较观察两组患者在经过治疗之后的肺部功能恢复情况、治疗效果以及患者的生活质量水平。结果两组患者在经过治疗之后,观察组患者的最大呼吸峰流速、1 s用力呼吸的容积以及最大呼气中段流量明显高于对照组患者的最大呼吸峰流速、1 s用力呼吸的容积以及最大呼气中段流量;观察组患者的生理功能评分、社会功能评分、角色限制评分以及总体健康评分明显高于对照组患者的生理功能评分、社会功能评分、角色限制评分以及总体健康评分;观察组患者的治疗有效率明显高于对照组患者的治疗有效率(P<0.05)。结论通过使用头孢他啶结合多索茶碱对慢性阻塞性肺气肿患者进行治疗,不仅仅可以改善患者的肺部功能(最大呼气峰流速、1 s用力呼吸的容积、最大呼气中段流量),还能够明显的提高患者的生活质量(生理功能、社会功能、角色限制以及总体健康),取得了非常好的治疗效果,值得在临床慢性阻塞性肺气肿中进行推广和应用。
Objective To investigate the effect of ceftazidime combined with doxofylline on the efficacy of patients with chronic obstructive emphysema. Methods Ninety-six patients with chronic emphysema who entered Sichuan Liangshan First People′s Hospital from July 2017 to May 2018 were selected as subjects. They were randomly divided into observation group and control group according to the treatment method. 48 cases in each group. The patients in the observation group were treated with ceftazidime combined with doxofylline. The recovery of lung function, the therapeutic effect and the quality of life of the patients after treatment were compared. Results After treatment, the maximum respiratory peak flow rate, the volume of 1 s forced breathing, and the maximum expiratory midstream flow of the observation group were significantly higher than the maximum respiratory peak flow rate of the control group, the volume of 1 s forced breathing, and the maximum call. Mid-gas flow;the physiological function score, social function score, role restriction score, and overall health score of the observation group were significantly higher than the physiological function score, social function score, role limit score, and overall health score of the control group; The treatment efficiency was significantly higher than that of the control group(P<0.05). Conclusion The treatment of patients with chronic obstructive emphysema by using ceftazidime combined with doxofylamine can not only improve the lung function of patients(maximum peak expiratory flow, volume of 1 s forced breathing, maximum mid-expiratory mid-flow). It can also significantly improve the patient's quality of life(physiological function, social function, role limitation and overall health), and has achieved very good therapeutic effects, which is worthy of promotion and application in clinical chronic obstructive emphysema.
Objective To investigate the effect of ceftazidime combined with doxofylline on the efficacy of patients with chronic obstructive emphysema. Methods Ninety-six patients with chronic emphysema who entered Sichuan Liangshan First People′s Hospital from July 2017 to May 2018 were selected as subjects. They were randomly divided into observation group and control group according to the treatment method. 48 cases in each group. The patients in the observation group were treated with ceftazidime combined with doxofylline. The recovery of lung function, the therapeutic effect and the quality of life of the patients after treatment were compared. Results After treatment, the maximum respiratory peak flow rate, the volume of 1 s forced breathing, and the maximum expiratory midstream flow of the observation group were significantly higher than the maximum respiratory peak flow rate of the control group, the volume of 1 s forced breathing, and the maximum call. Mid-gas flow;the physiological function score, social function score, role restriction score, and overall health score of the observation group were significantly higher than the physiological function score, social function score, role limit score, and overall health score of the control group; The treatment efficiency was significantly higher than that of the control group(P<0.05). Conclusion The treatment of patients with chronic obstructive emphysema by using ceftazidime combined with doxofylamine can not only improve the lung function of patients(maximum peak expiratory flow, volume of 1 s forced breathing, maximum mid-expiratory mid-flow). It can also significantly improve the patient's quality of life(physiological function, social function, role limitation and overall health), and has achieved very good therapeutic effects, which is worthy of promotion and application in clinical chronic obstructive emphysema.
引文
[1]陈蓉,冯钰.头孢他啶联合多索茶碱治疗对慢性阻塞性肺气肿患者外周血TNF-α、PDGF-B水平的影响[J].广西医科大学学报,2017,34(11):1604-1607.
[2]王芳,呙晓梅,朱可辉.多索茶碱联合头孢他啶治疗老年慢性肺气肿对肺功能及预后的影响[J].医学理论与实践,2017,30(24):3643-3644.
[3]徐春曦.多索茶碱联合头孢他啶治疗老年慢性肺气肿的临床效果观察[J].现代养生,2017(18):89.
[4]李久喜.多索茶碱联合头孢他啶治疗老年慢性肺气肿的临床观察[J].北方药学,2018,15(3):27-28.
[5]周军.多索茶碱联合头孢他啶治疗老年慢性肺气肿的疗效分析[J].临床医药文献电子杂志,2017,4(27):5283-5284.
[6]季芳.多索茶碱联合头孢他啶治疗老年慢性肺气肿患者的临床效果[J].医疗装备,2017,30(9):109-110.
[7]唐丽霞,周曙华,江雪红,等.1例慢性阻塞性肺疾病急性加重期老年患者的药学监护[J].中国药物应用与监测,2013(6):315-317.
[8]王彦雄.多索茶碱联合环丙沙星治疗慢性阻塞性肺气肿的疗效观察[J].临床医学研究与实践,2017,2(25):47-48.
[9]呼树国.苏子降气丸联合多索茶碱片治疗慢性阻塞性肺气肿的临床研究[J].中西医结合心血管病电子杂志,2016,4(7):119-121.
[10]叶琳.苏子降气丸联合多索茶碱片治疗慢性阻塞性肺气肿的临床研究[J].现代药物与临床,2015(2):166-170.
[11]马国选.苏子降气丸联合多索茶碱片治疗慢性阻塞性肺气肿的临床研究[J].生物技术世界,2015(11):184.
[12]赵俊,李永成.多索茶碱联合呼吸功能锻炼治疗肺气肿引起的呼吸衰竭患者对临床疗效、肺功能及血液相关指标的影响[J].实用临床医药杂志,2017,21(3):19-21.
[13]孙大圣.多索茶碱结合头孢他啶治疗老年慢性肺气肿患者的临床观察[J].中西医结合心血管病电子杂志,2017,5(36):106-108.
[14]腾小宝,韩明锋,时靖峰,等.多索茶碱联合头孢他啶治疗老年慢性肺气肿的临床观察[J].中国药房,2016,27(24):3359-3361.
[15]吴丽霞.多索茶碱、头孢他啶联合给药对老年慢性肺气肿的临床治疗效果分析[J].临床医药文献电子杂志,2018(27):29.
[2]王芳,呙晓梅,朱可辉.多索茶碱联合头孢他啶治疗老年慢性肺气肿对肺功能及预后的影响[J].医学理论与实践,2017,30(24):3643-3644.
[3]徐春曦.多索茶碱联合头孢他啶治疗老年慢性肺气肿的临床效果观察[J].现代养生,2017(18):89.
[4]李久喜.多索茶碱联合头孢他啶治疗老年慢性肺气肿的临床观察[J].北方药学,2018,15(3):27-28.
[5]周军.多索茶碱联合头孢他啶治疗老年慢性肺气肿的疗效分析[J].临床医药文献电子杂志,2017,4(27):5283-5284.
[6]季芳.多索茶碱联合头孢他啶治疗老年慢性肺气肿患者的临床效果[J].医疗装备,2017,30(9):109-110.
[7]唐丽霞,周曙华,江雪红,等.1例慢性阻塞性肺疾病急性加重期老年患者的药学监护[J].中国药物应用与监测,2013(6):315-317.
[8]王彦雄.多索茶碱联合环丙沙星治疗慢性阻塞性肺气肿的疗效观察[J].临床医学研究与实践,2017,2(25):47-48.
[9]呼树国.苏子降气丸联合多索茶碱片治疗慢性阻塞性肺气肿的临床研究[J].中西医结合心血管病电子杂志,2016,4(7):119-121.
[10]叶琳.苏子降气丸联合多索茶碱片治疗慢性阻塞性肺气肿的临床研究[J].现代药物与临床,2015(2):166-170.
[11]马国选.苏子降气丸联合多索茶碱片治疗慢性阻塞性肺气肿的临床研究[J].生物技术世界,2015(11):184.
[12]赵俊,李永成.多索茶碱联合呼吸功能锻炼治疗肺气肿引起的呼吸衰竭患者对临床疗效、肺功能及血液相关指标的影响[J].实用临床医药杂志,2017,21(3):19-21.
[13]孙大圣.多索茶碱结合头孢他啶治疗老年慢性肺气肿患者的临床观察[J].中西医结合心血管病电子杂志,2017,5(36):106-108.
[14]腾小宝,韩明锋,时靖峰,等.多索茶碱联合头孢他啶治疗老年慢性肺气肿的临床观察[J].中国药房,2016,27(24):3359-3361.
[15]吴丽霞.多索茶碱、头孢他啶联合给药对老年慢性肺气肿的临床治疗效果分析[J].临床医药文献电子杂志,2018(27):29.