寻常型天疱疮并发甲下出血1例
摘要
<正>1病历摘要患者女,48岁。因口腔糜烂4年,头部丘疹、水疱2年7个月,伴甲下出血1个月就诊。患者4年前无明显诱因口腔出现糜烂,伴疼痛,多次自行治疗,无明显好转。2年9个月前,头部出现丘疹、丘疱疹,伴瘙痒,逐渐波及全身。在我院经皮损组织病理检查诊断为天疱疮。后多次于外院住院治疗,经地塞米松每日9.75~10.5mg,联合环磷酰胺每周600 mg连续2周治疗,病情好转后出院。后患者病情反复,于2015年3月24日入我科住院治疗。既往无类似疾病史,否认有外伤病史。
引文
[1]张学军,陆洪光,高兴华.皮肤性病学[M].8版.北京:人民卫生出版社,2013:196.
[2]张建忠,高兴华.皮肤性病学[M].北京:人民卫生出版社,2015:261.
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[4]Patsatsi A,Sotiriou E,Devliotou-Panagiotidou D,et al.Pemphigus vulgaris affecting 19 nails[J].Clinical and Experimental Dermatology,2008,34(2):202-205.
[5]杨海平,顾恒,贾虹,等.寻常型天疱疮并甲下出血一例[J].中华皮肤科杂志,1998,31(4):217.
[6]朱晓浚,王亮春.寻常型天疱疮多个甲下出血2例[J].临床皮肤科杂志,2012,41(3)
[7]Fulton RA,Campbell I,Caryland D,et al.Nail bed immunofluorescence in pemphigus vulgaris[J].Acta Derm Venereol(Stockh),1983,63:170-172.
[8]Lee HE,Wong WR,Lee MC,et al.Acute paronyehia heralding the exacerbation of pemphigus vulgaris[J].Int J Clin Pract,2004,58(12):1174-1176.
[9]Engineer L,Norton LA,Ahmed AR.Nail involvement in pemphigus vulgaris[J].J Am Acad Dermmol,2000,43(3):529-535.
[2]张建忠,高兴华.皮肤性病学[M].北京:人民卫生出版社,2015:261.
[3]Schlesinger N,Katz M,Ingber A.Clinical Investigations Nail involvement in pemphigus vulgaris[J].Br J Dermatol,2002,146(3):836-839.
[4]Patsatsi A,Sotiriou E,Devliotou-Panagiotidou D,et al.Pemphigus vulgaris affecting 19 nails[J].Clinical and Experimental Dermatology,2008,34(2):202-205.
[5]杨海平,顾恒,贾虹,等.寻常型天疱疮并甲下出血一例[J].中华皮肤科杂志,1998,31(4):217.
[6]朱晓浚,王亮春.寻常型天疱疮多个甲下出血2例[J].临床皮肤科杂志,2012,41(3)
[7]Fulton RA,Campbell I,Caryland D,et al.Nail bed immunofluorescence in pemphigus vulgaris[J].Acta Derm Venereol(Stockh),1983,63:170-172.
[8]Lee HE,Wong WR,Lee MC,et al.Acute paronyehia heralding the exacerbation of pemphigus vulgaris[J].Int J Clin Pract,2004,58(12):1174-1176.
[9]Engineer L,Norton LA,Ahmed AR.Nail involvement in pemphigus vulgaris[J].J Am Acad Dermmol,2000,43(3):529-535.