双氯芬酸钠联合聚乙烯醇滴眼液对白内障术后干眼症的效果及泪膜破裂时间的影响
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摘要
目的观察双氯芬酸钠和聚乙烯醇滴眼液对白内障术后干眼症的效果及泪膜破裂时间的影响。方法 86例白内障术后干眼症患者单用聚乙烯醇滴眼液(对照组)或联用双氯芬酸钠滴眼液(观察组)治疗,比较两组的临床症状评分、泪膜破裂时间、角膜荧光染色评分。结果治疗1、2、3周后,两组的临床症状评分和角膜荧光染色评分明显降低,而泪膜破裂时间延长,其中观察组明显优于对照组(P<0.01或0.05)。结论联用双氯芬酸钠和聚乙烯醇滴眼液可缓解白内障术后干眼症及延长泪膜破裂时间。
Objective To observe the effect of diclofenac sodium and polyvinyl alcohol eye drops on dry eye and tear break-up time(TBUT) after cataract surgery. Methods Eighty-six patients with dry eyes following cataract surgery were randomly treated with polyvinyl alcohol eye drops(control group) or diclofenac sodium and polyvinyl alcohol eye drops(observation group). Clinical symptom score, TBUT, and corneal fluorescence staining were compared between two groups.Results Clinical symptom score and corneal fluorescence staining were decreased, while TBUT increased in two groups 1-3 weeks after therapy, especially in observation group(P<0.01 or 0.05). Conclusion Combined diclofenac sodium and polyvinyl alcohol eye drops can improve clinical symptoms and TBUT in patients with dry eyes following cataract surgery.
Objective To observe the effect of diclofenac sodium and polyvinyl alcohol eye drops on dry eye and tear break-up time(TBUT) after cataract surgery. Methods Eighty-six patients with dry eyes following cataract surgery were randomly treated with polyvinyl alcohol eye drops(control group) or diclofenac sodium and polyvinyl alcohol eye drops(observation group). Clinical symptom score, TBUT, and corneal fluorescence staining were compared between two groups.Results Clinical symptom score and corneal fluorescence staining were decreased, while TBUT increased in two groups 1-3 weeks after therapy, especially in observation group(P<0.01 or 0.05). Conclusion Combined diclofenac sodium and polyvinyl alcohol eye drops can improve clinical symptoms and TBUT in patients with dry eyes following cataract surgery.
引文
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[3]崔健怡,胡水清.普拉洛芬联合玻璃酸钠治疗白内障术后干眼症的临床疗效分析[J].中国药物经济学, 2018, 13(12):71-73.
[4]邬永娟,黎作为,李德全.超声乳化联合人工晶体植入术治疗高度近视眼白内障患者的疗效观察[J].广东医学院学报, 2013, 31(3):286-287.
[5]徐为海,高桂芬,代丽玲.白内障超声乳化术后局部用药治疗白内障患者干眼症的效果观察[J].中国实用医药, 2018,13(33):104-106.
[6]王建新,佟宝莉.双氯芬酸钠联合聚乙烯醇滴眼液治疗白内障术后干眼症的临床效果分析[J].世界最新医学信息文摘, 2018, 18(91):95, 98.
[7]王蕊,绳月华.双氯芬酸钠联合聚乙烯醇滴眼液治疗白内障术后干眼症200例[J].当代医学, 2018, 24(11):158-160.
[8]唐春舟,徐学东,任洁,等.聚乙烯醇滴眼液预防超声乳化白内障摘除术后干眼症267例分析[J].南通大学学报(医学版), 2017, 37(6):592-594.
[9]李影.聚乙烯醇滴眼液联合中医辨证治疗白内障术后干眼症的疗效分析[J].中医临床研究, 2017, 9(25):11-13.
[10]周和平,汪银彩.双氯芬酸钠联合人工泪液治疗白内障术后干眼症的疗效分析[J].中外医疗, 2017, 36(5):135-137.