改良口腔护理在预防急性淋巴细胞白血病MTX化疗后口腔黏膜炎的效果探讨
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摘要
目的:探讨分析改良口腔护理对急性淋巴细胞白血病(ALL)甲氨蝶呤(MTX)化疗后口腔黏膜炎的预防效果。方法:随机选取笔者所在科54例接受MTX化疗的急性淋巴白血病患者,按化疗顺序编号分组,单数者为常规组(n=27),实施常规口腔护理;双数者为观察组(n=27),实施改良式口腔护理,比较两组临床护理效果。结果:观察组口腔黏膜炎发病率、重度口腔黏膜炎发生率均明显低于常规组,差异有统计学意义(P<0.05);观察组患者口腔卫生清洁率高于常规组,差异有统计学意义(P<0.05)。结论:急性淋巴细胞白血病患者在接受MTX化疗的同时配合改良式口腔护理,可有效预防口腔黏膜炎发生,且能降低口腔黏膜炎的严重程度,值得在临床中推广。
Objective:To explore the effect of improved oral care on oral mucositis after MTX chemotherapy in acute lymphoblastic leukemia.Method:54 patients with ALL after MTX chemotherapy in the author's department were randomly divided into routine group(n=27,routine oral care)and observation group(n=27,improved oral care) according to the sequence number of chemotherapy.Result:The oral mucositis incidence rate and the severe oral mucositis incidence rate of observation group was lower than those of routine group,the differences were statistically significant(P<0.05);the oral health compliance rate of observation group was higher than that of routine group,the difference was statistically significant(P<0.05).Conclusion:Improved oral care can effectively prevent the occurrence of oral mucositis,reduce the severity of oral mucositis.
Objective:To explore the effect of improved oral care on oral mucositis after MTX chemotherapy in acute lymphoblastic leukemia.Method:54 patients with ALL after MTX chemotherapy in the author's department were randomly divided into routine group(n=27,routine oral care)and observation group(n=27,improved oral care) according to the sequence number of chemotherapy.Result:The oral mucositis incidence rate and the severe oral mucositis incidence rate of observation group was lower than those of routine group,the differences were statistically significant(P<0.05);the oral health compliance rate of observation group was higher than that of routine group,the difference was statistically significant(P<0.05).Conclusion:Improved oral care can effectively prevent the occurrence of oral mucositis,reduce the severity of oral mucositis.
引文
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[9]董桐俊,刘卫华,闫微,等.大剂量甲氨喋呤化疗致口腔黏膜炎的观察与护理[J].护理实践与研究,2012,9(12):96-97.
[10]何建群,方珍,吴燕,等.冰镇液口腔护理加口腔喷雾对预防乳腺癌化疗患者口腔黏膜炎的作用[J].中国现代医生,2016,54(11):150-153,163.
[2]周晔敏,周馥敏.大剂量甲氨蝶呤在儿童急性淋巴细胞性白血病化疗中的疗效观察及不良反应护理[J].海峡药学,2012,24(2):201-203.
[3]庞晓阳.大剂量甲氨蝶呤化疗引起口腔炎的护理体会[J].中国实用医药,2012,7(2):233.
[4]赵慧慧,洪鸣,钱思轩.世界卫生组织2016年急性髓系白血病及淋巴细胞白血病/淋巴瘤分类更新解读[J].中国实用内科杂志,2016,36(8):654-657.
[5]单倩倩.鼻咽癌患者放化疗致口腔粘膜炎的护理[J].辽宁医学院学报,2016,37(3):96-97.
[6]陈永娟,覃靖彬.两种漱口液对经口气管插管患者行口腔护理的效果研究[J].河北医药,2016,38(6):950-952.
[7]刘凤菊,王慧丽.对急性白血病鞘内注射疗效的护理探讨[J].河南职工医学院学报,2013,25(2):188-189.
[8]李晓芳,牛俊丽,申巧红,等.大剂量甲氨蝶呤化疗致口腔黏膜溃疡的护理[J].基层医学论坛,2011,15(36):1185.
[9]董桐俊,刘卫华,闫微,等.大剂量甲氨喋呤化疗致口腔黏膜炎的观察与护理[J].护理实践与研究,2012,9(12):96-97.
[10]何建群,方珍,吴燕,等.冰镇液口腔护理加口腔喷雾对预防乳腺癌化疗患者口腔黏膜炎的作用[J].中国现代医生,2016,54(11):150-153,163.