补阳还五汤方穴位贴敷对气虚血瘀型脑卒中患者相关指标的影响
|
摘要
目的探讨补阳还五汤方穴位贴敷对气虚血瘀型脑卒中患者中医症状评分、神经功能缺损评分(NIHSS)和日常生活活动能力评分。方法选取111例气虚血瘀型脑卒中患者,按照随机数字表法分为对照组(n=55)和观察组(n=56)。对照组患者进行健康知识宣教和常规基础治疗,观察组患者则在对照组治疗基础上联合使用补阳还五汤穴位贴敷法进行治疗,观察2组患者治疗前后的日常生活活动能力评分、神经功能缺损评分、中医症状评分以及总有效率、复发率。结果治疗后,2组患者的中医症状评分、NIHSS评分、生活活动能力评分均优于治疗前(P <0.05),其中观察组患者的中医症状评分为(11.58±4.23)分,显著低于对照组的(13.22±7.01)分(P <0.05);NIHSS评分为(12.63±7.36)分,显著低于对照组的(10.25±4.83)分(P <0.05);生活活动能力评分为(59.85±19.77)分,显著高于对照组的(47.22±19.26)分(P <0.05)。观察组治疗后总有效率、复发率分别为87.50%、7.14%,显著优于对照组的69.09%、12.73%(P <0.05)。结论气虚血瘀型脑卒中患者采用补阳还五汤穴位贴敷法进行治疗,能够有效改善其中医症状评分和NIHSS评分、日常生活活动能力评分等指标,提高患者生活质量,减少复发。
Objective To study the effect of acupoint application of Buyang Huanwu decoction on TCM symptom score, neurologic deficit score(NIHSS) and activity of daily living of stroke patients with qi deficiency and blood stasis. Methods 111 cases of qi deficiency and blood stasis type of stroke patients were randomly divided into control group and observation group according to random number table method. The control group patients were conducted health knowledge education and treatment on a regular basis. On the basis of the treatment of the control group, the patients with the observation group were treated with the acupoint application of Buyang Huanwu decoction. The scores of activity of daily living, neurological deficit score, TCM symptom score, total effective rate and recurrence rate were observed before and after treatment in the two groups. Results After treatment, the scores of TCM symptom, NIHSS and activity of life in the two groups were better than those before treatment(P <0.05).The scores of TCM symptoms in the observation group were(11.58±4.23), it was significantly lower than that of control group(13.22±7.01)(P <0.05). The NIHSS score was(12.63±7.36), which was significantly lower than that in the control group(10.25±4.83)(P <0.05). The score of activity of living of the patients in the observation group were(59.85±19.77). It was significantly higher than that in the control group(47.22±19.26)(P <0.05).The total effective rate and the recurrence rate of the observation group were 87.50% and 7.14%, respectively, which was significantly better than 69.09% and 12.73% of the control group(P <0.05). Conclusion For the patients with apoplexy due to qi deficiency and blood stasis, the treatment with Buyang Huanwu decoction acupoint application can effectively improve the scores of TCM symptoms and NIHSS, the ability of daily life and so on, improve the quality of life and reduce recurrence.
Objective To study the effect of acupoint application of Buyang Huanwu decoction on TCM symptom score, neurologic deficit score(NIHSS) and activity of daily living of stroke patients with qi deficiency and blood stasis. Methods 111 cases of qi deficiency and blood stasis type of stroke patients were randomly divided into control group and observation group according to random number table method. The control group patients were conducted health knowledge education and treatment on a regular basis. On the basis of the treatment of the control group, the patients with the observation group were treated with the acupoint application of Buyang Huanwu decoction. The scores of activity of daily living, neurological deficit score, TCM symptom score, total effective rate and recurrence rate were observed before and after treatment in the two groups. Results After treatment, the scores of TCM symptom, NIHSS and activity of life in the two groups were better than those before treatment(P <0.05).The scores of TCM symptoms in the observation group were(11.58±4.23), it was significantly lower than that of control group(13.22±7.01)(P <0.05). The NIHSS score was(12.63±7.36), which was significantly lower than that in the control group(10.25±4.83)(P <0.05). The score of activity of living of the patients in the observation group were(59.85±19.77). It was significantly higher than that in the control group(47.22±19.26)(P <0.05).The total effective rate and the recurrence rate of the observation group were 87.50% and 7.14%, respectively, which was significantly better than 69.09% and 12.73% of the control group(P <0.05). Conclusion For the patients with apoplexy due to qi deficiency and blood stasis, the treatment with Buyang Huanwu decoction acupoint application can effectively improve the scores of TCM symptoms and NIHSS, the ability of daily life and so on, improve the quality of life and reduce recurrence.
引文
[1]王佩,宋志超,王翠,等.益气活血通络方配合康复训练治疗中风后遗症疗效观察[J].陕西中医,2013,34(2):155-156.
[2]BERLIT P.Neurological disorders and pregnancy[J].Fortschr Neurol Psychiatr,2016,84(2):103-111.
[3]江利敏,嵇朋,崔炜,等.血塞通联合补阳还五汤对缺血性脑中风的NIHSS及QLI的影响研究[J].时珍国医国药,2013,24(10):2394-2396.
[4]BEGGAN C,JABER K,LEADER M.Apoplexia uteri:a rarely described post-mortem finding[J].J Forensic Leg Med,2013,20(6):703-705.
[5]乔树真,韩祖成,宋志超,等.刚柔相济综合康复方案治疗中风病恢复期临床研究[J].陕西中医,2014,35(6):643-644.
[6]H?USSER L F.Empathy and mirror neurons:a view on contemporary neuropsychological empathy research[J].Prax Kinderpsychol Kinderpsychiatr,2012,61(5):322-335.
[7]周艳朋,张小建,焦雪蕾,等.补阳还五汤配合中医针灸治疗中风后肢体功能障碍的疗效[J].世界中医药,2018,13(1):183-185,189.
[8]ZHAO A M,QIU W R,MAO L J,et al.The efficacy and safety of Jiedu Tongluo granules for treating post-stroke depression with qi deficiency and blood stasis syndrome study protocol for a randomized controlled trial[J].Trials,2018,19(1):275.
[9]甘佳乐,徐武清,刘敬霞,等.中医药治疗脑梗死研究进展[J].吉林中医药,2016,36(2):214-216.
[10]LIU T L,LIU M N,XU X L,et al.Differential gene expression profiles between two subtypes of ischemic stroke with blood stasis syndromes[J].Oncotarget,2017,8(67):608-622.
[11]吴殷夏,孔雪倩,唐元如,等.穴位贴敷治疗气虚血瘀型中风疗效观察[J].上海针灸杂志,2016,35(5):504-506.
[12]DANG W T,XIE W G,ZHOU J G.Expression of PYCARDgene transcript variant mRNA in peripheral blood mononuclear cells of primary gout patients with different Chinese medicine syndromes[J].Chin J Integr Med,2018,24(1):24-31.
[13]李桂玲,名盛.补阳还五汤加减治疗中风后遗症60例临床观察[J].疾病监测与控制,2014,8(12):786-788.
[14]苏浩,赵苡,黄昭,等.针灸配合补阳还五汤治疗脑梗死后遗症68例临床观察[J].现代生物医学进展,2013,13(32):6347-6350.
[15]吴建峰.中西医结合治疗缺血性脑中风的疗效及对血液流变学指标的影响[J].现代中西医结合杂志,2014,23(34):3833-3834.
[16]荣立洋,王明三,李毓秋,等.中风病气虚血瘀证证候特点概述[J].吉林中医药,2016,36(7):750-752.
[2]BERLIT P.Neurological disorders and pregnancy[J].Fortschr Neurol Psychiatr,2016,84(2):103-111.
[3]江利敏,嵇朋,崔炜,等.血塞通联合补阳还五汤对缺血性脑中风的NIHSS及QLI的影响研究[J].时珍国医国药,2013,24(10):2394-2396.
[4]BEGGAN C,JABER K,LEADER M.Apoplexia uteri:a rarely described post-mortem finding[J].J Forensic Leg Med,2013,20(6):703-705.
[5]乔树真,韩祖成,宋志超,等.刚柔相济综合康复方案治疗中风病恢复期临床研究[J].陕西中医,2014,35(6):643-644.
[6]H?USSER L F.Empathy and mirror neurons:a view on contemporary neuropsychological empathy research[J].Prax Kinderpsychol Kinderpsychiatr,2012,61(5):322-335.
[7]周艳朋,张小建,焦雪蕾,等.补阳还五汤配合中医针灸治疗中风后肢体功能障碍的疗效[J].世界中医药,2018,13(1):183-185,189.
[8]ZHAO A M,QIU W R,MAO L J,et al.The efficacy and safety of Jiedu Tongluo granules for treating post-stroke depression with qi deficiency and blood stasis syndrome study protocol for a randomized controlled trial[J].Trials,2018,19(1):275.
[9]甘佳乐,徐武清,刘敬霞,等.中医药治疗脑梗死研究进展[J].吉林中医药,2016,36(2):214-216.
[10]LIU T L,LIU M N,XU X L,et al.Differential gene expression profiles between two subtypes of ischemic stroke with blood stasis syndromes[J].Oncotarget,2017,8(67):608-622.
[11]吴殷夏,孔雪倩,唐元如,等.穴位贴敷治疗气虚血瘀型中风疗效观察[J].上海针灸杂志,2016,35(5):504-506.
[12]DANG W T,XIE W G,ZHOU J G.Expression of PYCARDgene transcript variant mRNA in peripheral blood mononuclear cells of primary gout patients with different Chinese medicine syndromes[J].Chin J Integr Med,2018,24(1):24-31.
[13]李桂玲,名盛.补阳还五汤加减治疗中风后遗症60例临床观察[J].疾病监测与控制,2014,8(12):786-788.
[14]苏浩,赵苡,黄昭,等.针灸配合补阳还五汤治疗脑梗死后遗症68例临床观察[J].现代生物医学进展,2013,13(32):6347-6350.
[15]吴建峰.中西医结合治疗缺血性脑中风的疗效及对血液流变学指标的影响[J].现代中西医结合杂志,2014,23(34):3833-3834.
[16]荣立洋,王明三,李毓秋,等.中风病气虚血瘀证证候特点概述[J].吉林中医药,2016,36(7):750-752.