疏壅通络方联合腹针治疗肥胖2型糖尿病(痰热互结证)临床观察
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摘要
目的观察中药疏壅通络方联合腹针治疗肥胖2型糖尿病(痰热互结证)的临床疗效。方法将64例肥胖2型糖尿病患者(采用盐酸二甲双胍片治疗血糖不达标者),随机分为中药组(疏壅通络方)和针药组(疏壅通络方+腹针)各32例。观察治疗前后各组血糖、血脂、体重、胰岛素抵抗的指标变化。结果针药组有效率93.75%,中药组有效率81.25%,差异有统计学意义(P<0.05);两组治疗前后中医证候积分、血糖、血脂、体重、胰岛素抵抗指数组内对比差异有统计学意义(P<0.05,P<0.01);治疗后组间对比差异有统计学意义(P<0.05,P<0.01)。结论疏壅通络方能够改善肥胖2型糖尿病患者(痰热互结证)临床症状,调节糖脂代谢紊乱,减轻体重,提高胰岛素敏感性,在此基础上联合腹针疗效更佳。
Objective To observe the clinical efficacy of Shuyongtongluo Prescription combined with abdominal acupuncture for obese type 2 diabetes mellitus(T2 DM).Methods 64 obese patients with type 2 diabetes,who received metformin but whose blood glucose level was not up to standard,were divided into the control group and the acupuncture-medicine group with 32 cases in each group.The control group was given traditional Chinese medicine Shuyongtongluo Prescription,and the acupuncture-medicine group was given abdominal acupuncture treatment on the basis of the control group.The indexes of blood glucose,blood lipid,body weight and insulin resistance were observed before and after treatment.Results The total effective rate of acupuncture-medicine group was 93.75%,and that of the Chinese medicine group was 81.25%,the difference was statistically significant(P<0.05).After treatment,TCM syndrome integral,blood glucose,blood lipid,body weight and insulin resistance index were statistically significant(P<0.05 or P<0.01) between two group,the difference was statistically significant(P<0.05 or P<0.01).Conclusion Shuyongtongluo-Prescription can improve the symptoms of obese type 2 diabetic patients(phlegm-heat syndrome),regulate glucose and lipid metabolism disorders,reduce body weight and improve insulin sensitivity,and combined with abdominal acupuncture is better.
Objective To observe the clinical efficacy of Shuyongtongluo Prescription combined with abdominal acupuncture for obese type 2 diabetes mellitus(T2 DM).Methods 64 obese patients with type 2 diabetes,who received metformin but whose blood glucose level was not up to standard,were divided into the control group and the acupuncture-medicine group with 32 cases in each group.The control group was given traditional Chinese medicine Shuyongtongluo Prescription,and the acupuncture-medicine group was given abdominal acupuncture treatment on the basis of the control group.The indexes of blood glucose,blood lipid,body weight and insulin resistance were observed before and after treatment.Results The total effective rate of acupuncture-medicine group was 93.75%,and that of the Chinese medicine group was 81.25%,the difference was statistically significant(P<0.05).After treatment,TCM syndrome integral,blood glucose,blood lipid,body weight and insulin resistance index were statistically significant(P<0.05 or P<0.01) between two group,the difference was statistically significant(P<0.05 or P<0.01).Conclusion Shuyongtongluo-Prescription can improve the symptoms of obese type 2 diabetic patients(phlegm-heat syndrome),regulate glucose and lipid metabolism disorders,reduce body weight and improve insulin sensitivity,and combined with abdominal acupuncture is better.
引文
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[8]杨礼泛,黄龙坚,吕艳,等.腹针治疗单纯性肥胖临床疗效Meta分析[J].中医临床研究,2015,7(31):1.
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[2]中国肥胖问题工作组.中国成人超重和肥胖症预防控制指南[N].光明日报,2004-05-14(002).
[3]中华医学会内分泌分会肥胖学组.中国成人肥胖症防治专家共识[J].中华内分泌代谢杂志,2011,27(9):711.
[4]仝小林.糖尿病中医防治指南解读[M].北京:中国中医药出版社,2009:35.
[5]郑筱萸.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002:233.
[6]马锐,夏丽芳.通心络胶囊联合津力达颗粒对2型糖尿病患者血糖及血管内皮功能的影响[J].国际中医中药杂志,2016,38(5):411.
[7]杨媛,刘云霞.薄氏腹针治疗肥胖型2型糖尿病临床观察[J].中国针灸,2015,35(4):330.
[8]杨礼泛,黄龙坚,吕艳,等.腹针治疗单纯性肥胖临床疗效Meta分析[J].中医临床研究,2015,7(31):1.
[9]河恩惠.腹针治疗2型糖尿病胰岛素抵抗的临床观察[D].北京中医药大学硕士学位论文,2012.