ICU获得性肌无力的发病与中医“痿证”相关性的探讨
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摘要
根据痿证"肺热叶焦""湿热毒邪侵袭""内脏精血虚耗""脾病四肢不用""痰瘀阻络"等相关发病机制,结合促使ICU获得性肌无力(ICU-AW)发生的危险因素,探讨两者之间的相关性,并总结出润肺清热、解毒祛湿、补益脾肾、活血通络、通利关节等治法,旨在为ICU-AW的临床治疗提供思路。
According to the relevant pathogenesis of Wei syndrome, including lung heat scorching the lobes, dampness-heat-toxin invasion, deficiency of visceral essence and blood, extremities dysfunction due to spleen disease, and phlegm-stasis obstructing collateral, this study discussed the correlation between ICU acquired weakness and Wei Syndrome, based on risk factors that lead to the development of ICU-AW, and summarize some corresponding therapy of TCM, including clearing heat-moistening lung, resolving toxin-dispelling dampness, supplementing spleen-kidney, activating blood-dredging collaterals and lubricating the joints, in order to propose new ideas for the treatment of ICU-AW.
According to the relevant pathogenesis of Wei syndrome, including lung heat scorching the lobes, dampness-heat-toxin invasion, deficiency of visceral essence and blood, extremities dysfunction due to spleen disease, and phlegm-stasis obstructing collateral, this study discussed the correlation between ICU acquired weakness and Wei Syndrome, based on risk factors that lead to the development of ICU-AW, and summarize some corresponding therapy of TCM, including clearing heat-moistening lung, resolving toxin-dispelling dampness, supplementing spleen-kidney, activating blood-dredging collaterals and lubricating the joints, in order to propose new ideas for the treatment of ICU-AW.
引文
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[2]陈彦,邱海波.机械牵张在呼吸机相关性肺损伤中的作用机制[J].国外医学·呼吸系统分册,2004,24(5):332-335.
[3]关玲.降钙素原在危重症患者呼吸机相关性肺炎早期诊断价值的临床观察[J].齐齐哈尔医学院学报,2016,37(4):427-428.
[4]张子和.儒门事亲[M].天津:天津科技出版社,2000:10-11.
[5]Fenzi F,Latronico N,Refatti N,et al.Enhanced expression of Eselectin on the vascular endothelium of peripheral nerve in critically ill patients with neuromuscular disorders[J].Acta Neuropathol(Berl),2003(106):75-82.
[6]李际强,李俊.试论严重脓毒症与温病五死证的相关性及临床意义[J].辽宁中医杂志,2015,42(7):1234-1236.
[7]陈无择.医学全书·三因极一病证方论[M].北京:中国中医药出版社,2005:105-107.
[8]张景岳.景岳全书[M].北京:科学技术文献出版社,1996:574.
[9]刘清泉,李雁,寇兰俊.多脏器功能失常综合征中医病因病机及治法探讨[J].北京中医药大学学报,2000,23(3):57-58.
[10]Uncini A,Manzoli C,Notturno F,et al.Pitfalls in electrodiagnosis of Guillain-Barr syndrome subtypes[J].Neurol Neurosurg Psychiatry,2010,81(10):1157-1163.
[11]Staff NP,Engelstad J,Klein CJ,et al.Post-surgical inflammatory neuropathy[J].Brain,2010,133(10):2866-2880.
[12]张剑,陈雪楠.论“糖毒”性质与致病特点[J].北京中医药,2010,29(8):600-603.
[13]彭园国.糖尿病周围神经病变的病因机制研究探讨[J].中国中医药指南,2014,17(6):397-398.
[14]张锡纯.医学衷中参西录[M].石家庄:河北人民出版社,1974:118-121.