皮耐克在大面积烧伤患者关节部位瘢痕挛缩修复中的应用
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摘要
目的:探讨人工真皮皮耐克在大面积烧伤患者关节部位瘢痕挛缩修复中的应用效果。方法:在大面积烧伤患者关节部位瘢痕挛缩的修复应用中,一期行瘢痕切除联合皮耐克覆盖术,2~3周后行二期自体刃厚皮片移植术,观察手术效果。结果:移植皮片全部成活,修复关节功能良好,外观满意。远期随访供皮区仅轻度色素沉着,无瘢痕增生。结论:皮耐克联合自体刃厚皮移植在大面积烧伤患者关节部位瘢痕挛缩的修复中具有良好的应用价值,值得临床推广。
Objective To investigate the application effect of artificial dermis PELNAC in the repair of joints' scar in patients with large area burn. Methods Repairing of scar contracture of joint in patients with large area burn, scar excision combined with artificial dermis(PELNAC) transplantation was carried out on stage I, silicone of PELNAC membrane was removed and own split-thickness skin was grafted 2 to 3 weeks later, and then the operation effect were analysised. Results All grafts survived with satisfactory cosmetic and functional results, but only mild pigmentation appeared the donor site without scar hyperplasia in long term follow-up. Conclusion PELNAC combined with autologous thick skin graft has a good application value in the repair of scar contracture in patients with large area burn. It is worthy of clinical application
Objective To investigate the application effect of artificial dermis PELNAC in the repair of joints' scar in patients with large area burn. Methods Repairing of scar contracture of joint in patients with large area burn, scar excision combined with artificial dermis(PELNAC) transplantation was carried out on stage I, silicone of PELNAC membrane was removed and own split-thickness skin was grafted 2 to 3 weeks later, and then the operation effect were analysised. Results All grafts survived with satisfactory cosmetic and functional results, but only mild pigmentation appeared the donor site without scar hyperplasia in long term follow-up. Conclusion PELNAC combined with autologous thick skin graft has a good application value in the repair of scar contracture in patients with large area burn. It is worthy of clinical application
引文
[1]吴胜刚,李华涛,海恒林,等.皮能快愈敷料在瘢痕整形治疗中的应用[J].中国美容医学,2013,22(7):719-721.
[2]李伟萍,朱志祥,杨维琦,等.人工真皮模板在烧伤瘢痕整复中的应用[J].中华整形外科杂志,2006,5(3):210-212.
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[4]孙杨丹,梅海波,张溪英,等.人工真皮复合自体薄皮移植治疗皮肤软组织缺损[J].中国组织工程研究与临床康复,2011,15(24):4503-4506.
[5]陈欣,王晓军,王成,等.应用人工真皮和自体皮移植修复难愈性创面[J].中华烧伤外科杂志,2011,15(24):444-447.
[6]杨苓山,江榕.用人工真皮重建伴颅骨外露的全层头皮缺损[J].中国美容医学,2012,21(7):1099-1011.
[7]徐成,王峰,范锟铻,等.人工真皮联合自体刃厚皮片移植在烧伤瘢痕整复中的应用[J].江西医药,2015,50(7):676-677.
[8]陈杏晔,李凡,刘爱军,等.皮耐克组织工程皮肤修复皮肤创面的研究[J].广州中医药大学学报,2015,32(3):529-533.
[9]俞泽浩,肖亮,邹崎葩,等.人工真皮复合自体刃厚皮片修复关节处皮肤缺损创面的临床研究[J].重庆医学,2015,43(28):3727-3729.
[10]杨华莲,刘攀,丁华荣,等.人工真皮联合自体薄层皮片移植修复难愈性创面的疗效观察[J].中国临床新医学,2015,7(5):424-428.
[11]张卫峰,冯亚高,陶忠生,等.人工真皮修复手足部肌腱和骨外露创面[J].临床骨科杂志,2016,19(4):448-450.
[12]杨力,陈欣.应用人工真皮与自体刃厚皮移植修复全颅骨外露一例[J].中华损伤与修复杂志(电子版),2014,9(4):85.
[13]吴显培,张立,张新颖.人工真皮在骨、肌腱外露创面中的应用[J].海南医学,2016,27(5):807-809.
[14]朱邦中,曹东升,丁以春.人工真皮加超薄皮片修复复杂性骨外露创面临床应用[J].安徽医学,2016,32(12):1488-1490.
[15]张琮,周业平,于东宁,等.人工真皮联合自体薄断层皮片移植修复创伤后四肢重度软组织缺损临床观察[J].山东医药,2015,55(8):88-89.
[2]李伟萍,朱志祥,杨维琦,等.人工真皮模板在烧伤瘢痕整复中的应用[J].中华整形外科杂志,2006,5(3):210-212.
[3]陈志勇,李栋梁.皮耐克联合自体刃厚皮移植修复瘢痕切除后创面[J].中国美容医学,2014,23(17):1426-1427.
[4]孙杨丹,梅海波,张溪英,等.人工真皮复合自体薄皮移植治疗皮肤软组织缺损[J].中国组织工程研究与临床康复,2011,15(24):4503-4506.
[5]陈欣,王晓军,王成,等.应用人工真皮和自体皮移植修复难愈性创面[J].中华烧伤外科杂志,2011,15(24):444-447.
[6]杨苓山,江榕.用人工真皮重建伴颅骨外露的全层头皮缺损[J].中国美容医学,2012,21(7):1099-1011.
[7]徐成,王峰,范锟铻,等.人工真皮联合自体刃厚皮片移植在烧伤瘢痕整复中的应用[J].江西医药,2015,50(7):676-677.
[8]陈杏晔,李凡,刘爱军,等.皮耐克组织工程皮肤修复皮肤创面的研究[J].广州中医药大学学报,2015,32(3):529-533.
[9]俞泽浩,肖亮,邹崎葩,等.人工真皮复合自体刃厚皮片修复关节处皮肤缺损创面的临床研究[J].重庆医学,2015,43(28):3727-3729.
[10]杨华莲,刘攀,丁华荣,等.人工真皮联合自体薄层皮片移植修复难愈性创面的疗效观察[J].中国临床新医学,2015,7(5):424-428.
[11]张卫峰,冯亚高,陶忠生,等.人工真皮修复手足部肌腱和骨外露创面[J].临床骨科杂志,2016,19(4):448-450.
[12]杨力,陈欣.应用人工真皮与自体刃厚皮移植修复全颅骨外露一例[J].中华损伤与修复杂志(电子版),2014,9(4):85.
[13]吴显培,张立,张新颖.人工真皮在骨、肌腱外露创面中的应用[J].海南医学,2016,27(5):807-809.
[14]朱邦中,曹东升,丁以春.人工真皮加超薄皮片修复复杂性骨外露创面临床应用[J].安徽医学,2016,32(12):1488-1490.
[15]张琮,周业平,于东宁,等.人工真皮联合自体薄断层皮片移植修复创伤后四肢重度软组织缺损临床观察[J].山东医药,2015,55(8):88-89.