振动声激发超声导波评估皮质骨厚度的研究
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摘要
利用振动声激发超声导波来评价长骨是一种较新的思路。基于超声轴向传播方法,首先通过三维有限元法对导波在长骨中的传播进行建模仿真,再根据接收波形求解0A导波模式的相速度,最后依据理论相速度频散曲线得出皮质骨厚度。对不同厚度(2~6 mm)的骨板仿真的结果表明,皮质骨厚度估计的平均误差仅为2.61%。所提出的方法能够有效评估皮质骨厚度,对发展超声导波反演长骨的新技术具有一定意义,同时为临床超声导波长骨诊断的研究提供了新的思路。
Using vibro-acoustic excited ultrasonic guided waves to evaluate long bone is a new attempt. Based on ultrasonic axial transmission technique and three-dimension finite element method, simulations are performed to analyze the transmission characteristics of vibro-acoustic excited ultrasonic guided waves. Then the phase velocity of 0 A mode is calculated according to the simulated signals. Finally the bone thickness is obtained by comparing the measured velocity with the theoretical dispersion curve of phase velocity. Bone plates with different thickness(2~6 mm) are used in simulations. Results show that the average error of thickness estimation is only 2.61%. This method can effectively estimate cortical bone thickness and provide a new idea for the clinical application of ultrasonic guided waves in disease diagnosis of long bone.
Using vibro-acoustic excited ultrasonic guided waves to evaluate long bone is a new attempt. Based on ultrasonic axial transmission technique and three-dimension finite element method, simulations are performed to analyze the transmission characteristics of vibro-acoustic excited ultrasonic guided waves. Then the phase velocity of 0 A mode is calculated according to the simulated signals. Finally the bone thickness is obtained by comparing the measured velocity with the theoretical dispersion curve of phase velocity. Bone plates with different thickness(2~6 mm) are used in simulations. Results show that the average error of thickness estimation is only 2.61%. This method can effectively estimate cortical bone thickness and provide a new idea for the clinical application of ultrasonic guided waves in disease diagnosis of long bone.
引文
[1]LI Y, LIU D, XU K, et al. Transverse and oblique long bone fracture evaluation by low order ultrasonic guided waves:a simulation study[J]. BioMed Res Int, 2017, 2017(4):3083141.
[2]TA D, WANG W, WANG Y Y, et al. Measurement of the dispersion and attenuation of cylindrical ultrasonic guided waves in long bone[J]. Ultrasound med biol, 2009, 35(4):641-652.
[3]KILAPPAV,XUK,MOILANENP,etal.Assessmentofthe fundamental flexural guided wave in cortical bone by an ultrasonic axial-transmissionarraytransducer[J].UltrasoundinMedicine&Biology, 2013, 39(7):1223-1232.
[4]MOILANEN P, SALMI A, KILAPPA V, et al. Phased laser diode arraypermitsselectiveexcitationofultrasonicguidedwavesin coated bone-mimicking tubes[J]. Journal of Applied Physics, 2017,122(14):144901.
[5]FATEMIM,GREENLEAFJF.Ultrasound-stimulatedvibro-acoustic spectrography[J]. Science, 1998, 280(5360):82-85.
[6]ALIZAD A, WHALEY D H, GREENLEAF J F, et al. Potential applicationsofvibro-acoustographyinbreastimaging[J].Technology in Cancer Research&Treatment, 2005, 4(2):151-158.
[7]MITRIFG,KINNICKRR.Vibroacoustographyimagingof kidney stones in vitro[J]. IEEE Transactions on Biomedical Engineering, 2012, 59(1):248-54.
[8]ALIZAD A, URBAN M W, MORRIS J C, et al. In vivo, thyroid vibro-acoustography:a pilot study[J]. Bmc Medical Imaging, 2013,13(1):12.
[9]MACCABI A, TAYLOR Z, BAJWA N, et al. An examination of theelasticpropertiesoftissue-mimickingphantomsusingvibro-acoustographyandamusclemotorsystem[J].Reviewof Scientific Instruments, 2016, 87(2):341-350.
[10]MOILANENP.Ultrasonicguidedwavesinbone[J].IEEEtrans on UFFC, 2008, 55(6):1277-1286.
[11]XUK,TAD,MOILANENP,WANGW.Modeseparationof Lambwavesbasedondispersioncompensationmethod[J].J Acoust Soc Am, 2012, 131(4):2714-2722.
[12]SUZ,YEL,LUY.GuidedLambwavesforidentificationof damage in composite structures:a review[J]. Journal of Sound&Vibration, 2006, 295(3-5):753-780.
[13]VIKTOROV I A. Rayleigh and Lamb waves:physical theory and applications[M]. New York:Plenum Press, 1967.
[14]LAUGIERP,HA?ATG.Bonequantitativeultrasound[M].Dordrecht:Springer, 2011.
[15]刘珍黎,宋亮华,白亮,等.长骨中振动声激发超声导波的方法[J].物理学报, 2017, 66(15):169-176.LIUZhenli,SONGLianghua,BAILiang,etal.Vibro-acoustic stimulating ultrasonic guided waves in long bone[J]. Acta Phys Sin,2017, 66(15):169-176.
[2]TA D, WANG W, WANG Y Y, et al. Measurement of the dispersion and attenuation of cylindrical ultrasonic guided waves in long bone[J]. Ultrasound med biol, 2009, 35(4):641-652.
[3]KILAPPAV,XUK,MOILANENP,etal.Assessmentofthe fundamental flexural guided wave in cortical bone by an ultrasonic axial-transmissionarraytransducer[J].UltrasoundinMedicine&Biology, 2013, 39(7):1223-1232.
[4]MOILANEN P, SALMI A, KILAPPA V, et al. Phased laser diode arraypermitsselectiveexcitationofultrasonicguidedwavesin coated bone-mimicking tubes[J]. Journal of Applied Physics, 2017,122(14):144901.
[5]FATEMIM,GREENLEAFJF.Ultrasound-stimulatedvibro-acoustic spectrography[J]. Science, 1998, 280(5360):82-85.
[6]ALIZAD A, WHALEY D H, GREENLEAF J F, et al. Potential applicationsofvibro-acoustographyinbreastimaging[J].Technology in Cancer Research&Treatment, 2005, 4(2):151-158.
[7]MITRIFG,KINNICKRR.Vibroacoustographyimagingof kidney stones in vitro[J]. IEEE Transactions on Biomedical Engineering, 2012, 59(1):248-54.
[8]ALIZAD A, URBAN M W, MORRIS J C, et al. In vivo, thyroid vibro-acoustography:a pilot study[J]. Bmc Medical Imaging, 2013,13(1):12.
[9]MACCABI A, TAYLOR Z, BAJWA N, et al. An examination of theelasticpropertiesoftissue-mimickingphantomsusingvibro-acoustographyandamusclemotorsystem[J].Reviewof Scientific Instruments, 2016, 87(2):341-350.
[10]MOILANENP.Ultrasonicguidedwavesinbone[J].IEEEtrans on UFFC, 2008, 55(6):1277-1286.
[11]XUK,TAD,MOILANENP,WANGW.Modeseparationof Lambwavesbasedondispersioncompensationmethod[J].J Acoust Soc Am, 2012, 131(4):2714-2722.
[12]SUZ,YEL,LUY.GuidedLambwavesforidentificationof damage in composite structures:a review[J]. Journal of Sound&Vibration, 2006, 295(3-5):753-780.
[13]VIKTOROV I A. Rayleigh and Lamb waves:physical theory and applications[M]. New York:Plenum Press, 1967.
[14]LAUGIERP,HA?ATG.Bonequantitativeultrasound[M].Dordrecht:Springer, 2011.
[15]刘珍黎,宋亮华,白亮,等.长骨中振动声激发超声导波的方法[J].物理学报, 2017, 66(15):169-176.LIUZhenli,SONGLianghua,BAILiang,etal.Vibro-acoustic stimulating ultrasonic guided waves in long bone[J]. Acta Phys Sin,2017, 66(15):169-176.