冠脉CTA对降主动脉弹性的研究与冠脉病变支数的相关性
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摘要
目的:通过冠状动脉CT血管造影(冠脉CTA)检查,研究降主动脉弹性与冠状动脉病变支数的相关性。方法:选取行冠脉CTA检查的121例患者作为研究对象(男84例,女37例),按冠状动脉病变支数分4组(正常组;一支病变组;二支病变组;多支病变组)。将原始数据间隔5%RR间期进行重建,并测量每一时相肺动脉分叉处降主动脉的横截面积,计算出4个弹性指标(AoD、AoC、%Ao、%AoSI)。利用方差分析及S-N-K检验分析四组间降主动脉弹性参数的差异。结果:冠状动脉异常组的%Ao、AoD及AoC明显低于对照组,AoSI明显高于对照组;随着病变支数的增加冠状动脉异常组患者的%Ao、AoD及AoC数值逐渐减小,AoSI数值逐渐增加,各组间差异均具有统计学意义(P<0.05)。结论:降主动脉弹性与冠状动脉病变支数呈负相关。冠状动脉CTA可以定量评价动脉弹性值。
Objective: To study the correlation between the number of descending aorta and the number of coronary artery lesions by coronary CT angiography(coronary CTA), 176 patients(108 males and 68 females) from the coronary artery CTA examination in First Affiliated Hospital of Jiamusi University were selected as the coronary artery lesions. The data were divided into 4 groups(normal group, one lesion group, two lesion group, and multiple lesion group). The 5% RR interval of the original data was reconstructed, and the cross sectional area of the descending aorta in the bifurcation of each phase of the pulmonary artery was measured, and 4 elastic indexes(AoD, AoC,%Ao,%AoSI) were calculated. Variance analysis and S-N-K test were used to analyze the difference of elastic parameters of descending aorta between the four groups.Results: the%Ao, AoD and AoC of the coronary artery abnormal group were significantly lower than those in the control group, and the AoSI was significantly higher than that of the control group. With the increase of the number of lesions, the%Ao, AoD and AoC values gradually decreased, and the AoSI value increased gradually. The differences in each group were statistically significant(P<0.05). Conclusion: the descending aortic elasticity was negatively correlated with the number of coronary artery lesions. Coronary artery CTA can quantitatively evaluate arterial elasticity.
Objective: To study the correlation between the number of descending aorta and the number of coronary artery lesions by coronary CT angiography(coronary CTA), 176 patients(108 males and 68 females) from the coronary artery CTA examination in First Affiliated Hospital of Jiamusi University were selected as the coronary artery lesions. The data were divided into 4 groups(normal group, one lesion group, two lesion group, and multiple lesion group). The 5% RR interval of the original data was reconstructed, and the cross sectional area of the descending aorta in the bifurcation of each phase of the pulmonary artery was measured, and 4 elastic indexes(AoD, AoC,%Ao,%AoSI) were calculated. Variance analysis and S-N-K test were used to analyze the difference of elastic parameters of descending aorta between the four groups.Results: the%Ao, AoD and AoC of the coronary artery abnormal group were significantly lower than those in the control group, and the AoSI was significantly higher than that of the control group. With the increase of the number of lesions, the%Ao, AoD and AoC values gradually decreased, and the AoSI value increased gradually. The differences in each group were statistically significant(P<0.05). Conclusion: the descending aortic elasticity was negatively correlated with the number of coronary artery lesions. Coronary artery CTA can quantitatively evaluate arterial elasticity.
引文
[1] 赵锋仓,景蕴华.动脉弹性的检测方法[J].西藏医药杂志,2009,30(04):24-26.
[2] Orlova Ia A,Ageev FT.Arterial stiffness as a predictor of cardiovascular events in coronary heart disease[J].Ter A rkh,2010,82(1):68-73.
[3] 刘芳,于晶.双源CT冠状动脉成像对升主动脉弹性与广庄动脉狭窄程度的相关性研究[J].临床放射学杂志,2013,32(10):1436-1439.
[4] 贾崇富,王照谦.影像学检查在主动脉弹性功能评估中的价值[J].中老年心脑血管病杂志,2015,17(8):895-896.
[5] Ning LI,Thomas Beck,Jiuhong Chen,et al.Assesment of thoracic aortic elasticity;a preliminary study using electocardiographically gateddual-source CT[J].Eue Radiol,2011,21:1564-1572.
[6] lalande A,Khau VanKien P,Walker PM,et al.Compliance and pulse wave velocity assessed by MRI detect early aortic impairment in young patients with mutation of the smoth muscle myosin heavy chain[J].J Magn Reson Imaging,2008,28(5):1180-1187.
[7] 许传斌,陈晶,刘健,等.256层螺旋CT观测胃左动脉解剖变异及临床意义[J].黑龙江医药科学,2015,38(01):136-138.
[8] 邹欣瑾,何为,余传祥,等.动脉弹性功能参数检测与临床研究[J].生物医学工程学杂志,2010,27(03):565-569.
[2] Orlova Ia A,Ageev FT.Arterial stiffness as a predictor of cardiovascular events in coronary heart disease[J].Ter A rkh,2010,82(1):68-73.
[3] 刘芳,于晶.双源CT冠状动脉成像对升主动脉弹性与广庄动脉狭窄程度的相关性研究[J].临床放射学杂志,2013,32(10):1436-1439.
[4] 贾崇富,王照谦.影像学检查在主动脉弹性功能评估中的价值[J].中老年心脑血管病杂志,2015,17(8):895-896.
[5] Ning LI,Thomas Beck,Jiuhong Chen,et al.Assesment of thoracic aortic elasticity;a preliminary study using electocardiographically gateddual-source CT[J].Eue Radiol,2011,21:1564-1572.
[6] lalande A,Khau VanKien P,Walker PM,et al.Compliance and pulse wave velocity assessed by MRI detect early aortic impairment in young patients with mutation of the smoth muscle myosin heavy chain[J].J Magn Reson Imaging,2008,28(5):1180-1187.
[7] 许传斌,陈晶,刘健,等.256层螺旋CT观测胃左动脉解剖变异及临床意义[J].黑龙江医药科学,2015,38(01):136-138.
[8] 邹欣瑾,何为,余传祥,等.动脉弹性功能参数检测与临床研究[J].生物医学工程学杂志,2010,27(03):565-569.