足浴方治疗糖尿病性周围神经病变的临床研究
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摘要
目的探讨足浴方治疗糖尿病性周围神经病变(DPN)的临床疗效。方法 208例DPN患者,随机分为对照组和研究组各104例,对照组予甲钴胺片,0.5 mg/次,3次/d,口服;研究组在对照组基础上予中药足浴方治疗,两组均治疗4周。结果两组治疗后中医证候积分比较,研究组优于对照组(P <0.05);两组VPT治疗后比较,研究组优于对照组(P <0.05);两组MNCV(胫神经和腓总神经)、SNCV(胫后神经和腓肠神经)治疗后比较,研究组优于对照组(P <0.05)。两组疗效比较,研究组优于对照组(P <0.05)。结论足浴方可改善、修复受损的周围神经,改善DPN患者症状,提高神经传导速度,改善VPT,效果显著。
Objective To investigate the clinical efficacy of foot bath recipe in the treatment of diabetic peripheral neuropathy(DPN). Methods 208 patients with DPN were randomly divided into the control group and the study group, 104 cases in each group. The control group was given Mecobalamin Tablets, 0.5 mg/times, 3 times/d, orally. The study group was treated with Chinese medicine foot bath recipe on the basis of the control group. The two groups were treated for four weeks. Results The scores of TCM syndromes in the two groups after treatment were better than those in the control group(P < 0.05). Two groups of VPT were compared after treatment, the study group was better than the control group(P < 0.05). The two groups of MNCV(tibial and peroneal nerve) and SNCV(posterior tibial nerve and gastrocnemius nerve) were compared with the control group, and the study group was better than the control group(P < 0.05). The curative eff ect of the two groups was better than that of the control group(P < 0.05). Conclusion Foot bath recipe can improve and repair the damaged peripheral nerve, improve the symptoms of DPN patients, increase nerve conduction velocity, improve VPT, the eff ect is significant.
Objective To investigate the clinical efficacy of foot bath recipe in the treatment of diabetic peripheral neuropathy(DPN). Methods 208 patients with DPN were randomly divided into the control group and the study group, 104 cases in each group. The control group was given Mecobalamin Tablets, 0.5 mg/times, 3 times/d, orally. The study group was treated with Chinese medicine foot bath recipe on the basis of the control group. The two groups were treated for four weeks. Results The scores of TCM syndromes in the two groups after treatment were better than those in the control group(P < 0.05). Two groups of VPT were compared after treatment, the study group was better than the control group(P < 0.05). The two groups of MNCV(tibial and peroneal nerve) and SNCV(posterior tibial nerve and gastrocnemius nerve) were compared with the control group, and the study group was better than the control group(P < 0.05). The curative eff ect of the two groups was better than that of the control group(P < 0.05). Conclusion Foot bath recipe can improve and repair the damaged peripheral nerve, improve the symptoms of DPN patients, increase nerve conduction velocity, improve VPT, the eff ect is significant.
引文
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[14]张丽红.中西医结合治疗糖尿病周围神经病变临床疗效观察[J].深圳中西医结合杂志, 2016, 26(8):36-37.
[15]曹红蕾,施佩红.中药足浴对糖尿病性周围神经病变(DPN)的效果观察[J].海峡医药, 2015(1):87-88.
[16]王志强,庞国明,闫镛,等.糖尿病周围神经病变的中医证型分布规律研究[J].中医学报, 2011, 26(4):487-489.
[17]陈翠芝,王亚琼,裴友翠.足痹通络方治疗糖尿病性周围神经病变的疗效观察[J].世界中医药, 2017, 12(4):776-779.
[18]兰博雅,王国强,赵芸芸,等.活血化瘀通络法对糖尿病足神经病变影响的临床研究[J].时珍国医国药, 2015,26(12):2945-2946.
[19]王学妍,李明哲,冷玉杰.中药外洗(足浴)治疗糖尿病周围神经病变临床观察[J].辽宁中医药大学学报, 2017,19(9):159-161.
[20]王晓红.中药足浴配合甲钴胺治疗糖尿病周围神经病变的疗效观察[J].中国民间疗法, 2014, 22(7):49.
[2]张永文,韩康生,程燕.糖尿病周围神经病变的中医病因病机及证治[J].吉林中医药, 2014, 34(6):561-564.
[3]张贺成,魏苏.糖尿病周围神经病变诊断进展[J].中国医药导报, 2017, 14(2):45-48.
[4]王增梅,黄玉强,秦佑胜,等.糖尿病周围神经病变的中西医研究进展[J].湖南中医杂志, 2017, 33(2):162-164.
[5]尤良震,申国明,王浩,等.中医药治疗糖尿病周围神经病变[J].长春中医药大学学报, 2015(6):1160-1162.
[6]中华医学会糖尿病分会.中国2型糖尿病防治指南(2013年版)[J].中华糖尿病杂志, 2014, 6(7):447-498.
[7]吕仁和,赵进喜.糖尿病及其并发症中西医诊治学[M].北京:人民卫生出版社, 2014:645-646.
[8]中华人民共和国卫生部.中药新药临床研究指导原则[M].北京:中国医药科技出版社, 2002:236-237.
[9]高赛赛,杨宏,沈飞霞.中西医结合治疗糖尿病周围神经病变临床疗效分析[J].新中医, 2015, 47(12):96-98.
[10]张永健,徐江红,曹亮,等.灯盏细辛穴位注射治疗糖尿病周围神经病变[J].长春中医药大学学报, 2014, 30(1):98-100.
[11]黄飞平.中西医结合治疗糖尿病周围神经病变45例临床疗效观察[J].四川中医, 2013, 31(3):71-73.
[12]崔淼.中药足浴治疗2型糖尿病周围神经病变的临床观察[J].内蒙古中医药, 2014, 33(30):80.
[13]姚祈.补阳还五汤联合a-硫辛酸治疗气虚血瘀!脉络瘀阻型糖尿病周围神经病变临床疗效评价[J].中华中医药学刊, 2016, 34(5):1166-1168.
[14]张丽红.中西医结合治疗糖尿病周围神经病变临床疗效观察[J].深圳中西医结合杂志, 2016, 26(8):36-37.
[15]曹红蕾,施佩红.中药足浴对糖尿病性周围神经病变(DPN)的效果观察[J].海峡医药, 2015(1):87-88.
[16]王志强,庞国明,闫镛,等.糖尿病周围神经病变的中医证型分布规律研究[J].中医学报, 2011, 26(4):487-489.
[17]陈翠芝,王亚琼,裴友翠.足痹通络方治疗糖尿病性周围神经病变的疗效观察[J].世界中医药, 2017, 12(4):776-779.
[18]兰博雅,王国强,赵芸芸,等.活血化瘀通络法对糖尿病足神经病变影响的临床研究[J].时珍国医国药, 2015,26(12):2945-2946.
[19]王学妍,李明哲,冷玉杰.中药外洗(足浴)治疗糖尿病周围神经病变临床观察[J].辽宁中医药大学学报, 2017,19(9):159-161.
[20]王晓红.中药足浴配合甲钴胺治疗糖尿病周围神经病变的疗效观察[J].中国民间疗法, 2014, 22(7):49.