基于超声医学应用的声传播的研究
|
摘要
目的:近年来,含气泡液体的声衰减和色散广泛应用于生物医学领域,利用这一特性可以对某些生物组织进行超声成像,也对血流进行超声多普勒成像,基于含气泡液体的声学特性对生物医学应用的影响,研究了声波在含有气泡粘性液体内的传播。方法:当液体中入射一列声波时,气泡的存在将改变液体内的传声特性,依据球贝塞尔和汉克尔函数,利用分界面处声波传播引起的质点振动速度和应力为边界条件研究其传播。结果:求解了声波在气-液混合介质内传播的声学参数,均与气泡含量、声波频率及粘滞系数等因素有关;并得到不同频率下声波的传播速度及衰减系数随气泡含量的变化曲线。结论:气泡和声波的传播频率都会影响声波在混合介质内的传播;具体表现在相同频率下,气泡含量增加使声波的传播速度不断下降,而其衰减系数却不断增大;气泡含量一定时,随着声波频率的升高,声波的传播速度下降越来越明显,衰减系数不断增大,即声波的传播能量损失越来越大。所得结论将对超声在医学上的研究和广泛应用有重要的指导意义。
Objective: The characteristics of high acoustic attenuation and sound dispersion in bubble-liquid, have been widely used in the biomedical field; and these features can be help for ultrasound imaging of biological tissue, and Doppler ultrasonic imaging of blood flow; the properties of sound propagation are studied based on ultrasonic medical applications. Methods:When acoustic wave acts on the liquid with bubble, which will change the characteristic of sound propagation, propagation of sound is researched in the condition of the particle vibration velocity and the stress at the interface of bubble-liquid, according to Beisel and Hankel function, Results: Acoustic parameters are soluted in the gas- liquid mixed media, which associated with bubble content, the acoustic frequency and viscous coefficient;at last changing curve are got, which include attenuation coefficient and the propagation velocity of sound waves of different frequencies and the bubble content. Conclusions: acoustic wave are influenced by transmission frequency and bubbles in the mixed medium; At the same frequency, increasing of bubble content lead to propagation velocity sank down, on the other hand, attenuation coefficient generally increases; If the bubble content is certain, With the increasing of sound frequency, the acoustic wave propagation velocity is slowed down, and the attenuation coefficient increase, In other words, the propagation of the acoustic energy loss more and more. It is important to the research in medical ultrasound and widely used.
Objective: The characteristics of high acoustic attenuation and sound dispersion in bubble-liquid, have been widely used in the biomedical field; and these features can be help for ultrasound imaging of biological tissue, and Doppler ultrasonic imaging of blood flow; the properties of sound propagation are studied based on ultrasonic medical applications. Methods:When acoustic wave acts on the liquid with bubble, which will change the characteristic of sound propagation, propagation of sound is researched in the condition of the particle vibration velocity and the stress at the interface of bubble-liquid, according to Beisel and Hankel function, Results: Acoustic parameters are soluted in the gas- liquid mixed media, which associated with bubble content, the acoustic frequency and viscous coefficient;at last changing curve are got, which include attenuation coefficient and the propagation velocity of sound waves of different frequencies and the bubble content. Conclusions: acoustic wave are influenced by transmission frequency and bubbles in the mixed medium; At the same frequency, increasing of bubble content lead to propagation velocity sank down, on the other hand, attenuation coefficient generally increases; If the bubble content is certain, With the increasing of sound frequency, the acoustic wave propagation velocity is slowed down, and the attenuation coefficient increase, In other words, the propagation of the acoustic energy loss more and more. It is important to the research in medical ultrasound and widely used.
引文
[1]张怀文,王运来,戴相昆等.影像引导放疗中常用CT设备影像质量的比较分析[J].中国医学物理学杂志.2011,28(2):2523-2538.Zhang Huaiwen,Wang Yunlai,Dai Xiangkun et al.Comparative analysis of image guided radiotherapy used CT image quality[J].Chinese Journal of Medical Physics,2011,28(2):2523-2538.
[2]钱晓琴,杨光,夏泽等。实施超声造影成像结合多普勒血流频谱形态评价乳腺良恶性肿块的血流动力学特性[J].中国临床医学影像杂志。2006:17(6).Qian Xiao-qin,Yang Guang,Xia Ze et al.Rcal contrast ultrasound combined with blood spectrum morphology in determining the character of blood dynamics in breast tumor[J].Chin Clin Med Imaging.2006,17(6):327-330
[3]邢晋放,杜联芳,姜露莹等.移植肾慢性排斥的Sono Vue超声造影临床研究[J].中国医学影像技术.2008,24(5):728-730.Xing Jinfang,Du Lian-fang,Jiang Lu-ying et al.Clinical study of chronic rejection of transplant kidney using sonovue contrast-enhanced ultrasound[J].Chin J Med Imaging Technol.2008,24(5):728-730.
[4]邵玉红,王彬.颈动脉血流的三维彩色多普勒成像研究[J].中国超声医学杂志2004,20(4):292-294.Color Doppler sonographic application for revealing vascular complications in liver transplantation.Chinese J Ultrasound Med.2004,20(4):292-294.
[5]孟贇,白景峰,陈亚珠.双层组织中相控聚焦超声声场分布的建模与计算[J].中国医学物理学杂志.2011,28(2):2567-2570.Meng Yun,Bai Jingfeng,Chen Yazhu.Phase control focusing ultrasonic field modeling and calculation of double tissues[J].Chinese Journal of Medical Physics,2011,28(2):2567-2570..
[6]陈道生,吴锦城.超声空化及其生物效应[J].中国医学物理学杂志.1987,4(3):37-39.Chen Daosheng,Wu Jincheng.Ultrasonic cavitation and biological effect[J].Chinese Journal of Medical Physics.1987,4(3):37-39.
[7]王建勤,李三兰.诊断超声的生物效应与其安全性[J].中国误诊学杂志.2002,2(10):1478-1479.Wang Jianqin,Li Sanlan.Biological effect and safety of diagnostic ultrasound[J].Chinese Journal of Misdiagnostics.2002,2(10):1478~1479.
[8]Ichihara M,Kameda M.Propagation of acoustic waves in visco-elastic two-phase system:influences of the liquid viscosity and the internal diffusion[J].Journal of Volcanology and Geothermal Research,2004,137:73-91.Ichihara M,Kameda M.两相粘滞弹性系统内的声传播:液体粘性和内扩散的影响[J].火山学和地热研究杂志,2004,137:73-91.
[9]王飞,高嵩.压缩传感理论在磁共振成像技术中的应用[J].中国医学物理学杂志,2012,29(6):3755-3758.Wang Fei,Gao Song.Application of compressed sensing theory in MRI technique[J].Chinese Journal of Medical Physics,2012,29(6):3755-3758.
[10]王成会,林书玉.空化对液体传声特性的影响[J].陕西师范大学学报(自然科学版),2008,36(5):30-34.Wang Chenghui,Lin Shuyu.Influence of cavitation on the characteristic of sound propagation in liquids[J].Journal of Shaanxi Normal University(Natural Science Edit ion),2008,36(5):30-34.
[11]王勇,林书玉,张小丽.声波在含气泡液体中的线性传播[J].物理学报,2013,62(6):0643041-0643045.Wang Yong,Lin Shuyu,Zhang Xiaoli.Linear wave propagation in bubbly liquid[J].Acta Phys.Sin.2013,62(6):0643041-0643045
[12]王成会,林书玉.容器形状对液体声波的影响[J].陕西师范大学学报(自然科学版),2010,38(2):29-34.Wang Chenghui,Lin Shuyu.Influence of container's shape on the sound in liquids[J].Journal of Shaanxi Normal University(Natural Science Edit ion),2010,38(2):29-34.
[13]姚文苇.气泡对声传播影响的研究[J].陕西教育学院学报,2008,24(1):107-109.Yao Wenwei.The Effect of Bubble to Propagation of Acoustic Wave[J].Journal of Shaanxi institute of education,2008,24(1):107-109.
[14]李灿苹,刘学伟,杨丽等.气泡半径和含量对含气泡海水声波波速的影响[J].现代地质,2010,24(3):528-533.Li Canping,Liu Xuewei,Yang Li et al.Study on the bubble radius and content effect on the acoustic velocity of sea water with bubbles[J].Geoscience,2010,24(3):528-533.
[2]钱晓琴,杨光,夏泽等。实施超声造影成像结合多普勒血流频谱形态评价乳腺良恶性肿块的血流动力学特性[J].中国临床医学影像杂志。2006:17(6).Qian Xiao-qin,Yang Guang,Xia Ze et al.Rcal contrast ultrasound combined with blood spectrum morphology in determining the character of blood dynamics in breast tumor[J].Chin Clin Med Imaging.2006,17(6):327-330
[3]邢晋放,杜联芳,姜露莹等.移植肾慢性排斥的Sono Vue超声造影临床研究[J].中国医学影像技术.2008,24(5):728-730.Xing Jinfang,Du Lian-fang,Jiang Lu-ying et al.Clinical study of chronic rejection of transplant kidney using sonovue contrast-enhanced ultrasound[J].Chin J Med Imaging Technol.2008,24(5):728-730.
[4]邵玉红,王彬.颈动脉血流的三维彩色多普勒成像研究[J].中国超声医学杂志2004,20(4):292-294.Color Doppler sonographic application for revealing vascular complications in liver transplantation.Chinese J Ultrasound Med.2004,20(4):292-294.
[5]孟贇,白景峰,陈亚珠.双层组织中相控聚焦超声声场分布的建模与计算[J].中国医学物理学杂志.2011,28(2):2567-2570.Meng Yun,Bai Jingfeng,Chen Yazhu.Phase control focusing ultrasonic field modeling and calculation of double tissues[J].Chinese Journal of Medical Physics,2011,28(2):2567-2570..
[6]陈道生,吴锦城.超声空化及其生物效应[J].中国医学物理学杂志.1987,4(3):37-39.Chen Daosheng,Wu Jincheng.Ultrasonic cavitation and biological effect[J].Chinese Journal of Medical Physics.1987,4(3):37-39.
[7]王建勤,李三兰.诊断超声的生物效应与其安全性[J].中国误诊学杂志.2002,2(10):1478-1479.Wang Jianqin,Li Sanlan.Biological effect and safety of diagnostic ultrasound[J].Chinese Journal of Misdiagnostics.2002,2(10):1478~1479.
[8]Ichihara M,Kameda M.Propagation of acoustic waves in visco-elastic two-phase system:influences of the liquid viscosity and the internal diffusion[J].Journal of Volcanology and Geothermal Research,2004,137:73-91.Ichihara M,Kameda M.两相粘滞弹性系统内的声传播:液体粘性和内扩散的影响[J].火山学和地热研究杂志,2004,137:73-91.
[9]王飞,高嵩.压缩传感理论在磁共振成像技术中的应用[J].中国医学物理学杂志,2012,29(6):3755-3758.Wang Fei,Gao Song.Application of compressed sensing theory in MRI technique[J].Chinese Journal of Medical Physics,2012,29(6):3755-3758.
[10]王成会,林书玉.空化对液体传声特性的影响[J].陕西师范大学学报(自然科学版),2008,36(5):30-34.Wang Chenghui,Lin Shuyu.Influence of cavitation on the characteristic of sound propagation in liquids[J].Journal of Shaanxi Normal University(Natural Science Edit ion),2008,36(5):30-34.
[11]王勇,林书玉,张小丽.声波在含气泡液体中的线性传播[J].物理学报,2013,62(6):0643041-0643045.Wang Yong,Lin Shuyu,Zhang Xiaoli.Linear wave propagation in bubbly liquid[J].Acta Phys.Sin.2013,62(6):0643041-0643045
[12]王成会,林书玉.容器形状对液体声波的影响[J].陕西师范大学学报(自然科学版),2010,38(2):29-34.Wang Chenghui,Lin Shuyu.Influence of container's shape on the sound in liquids[J].Journal of Shaanxi Normal University(Natural Science Edit ion),2010,38(2):29-34.
[13]姚文苇.气泡对声传播影响的研究[J].陕西教育学院学报,2008,24(1):107-109.Yao Wenwei.The Effect of Bubble to Propagation of Acoustic Wave[J].Journal of Shaanxi institute of education,2008,24(1):107-109.
[14]李灿苹,刘学伟,杨丽等.气泡半径和含量对含气泡海水声波波速的影响[J].现代地质,2010,24(3):528-533.Li Canping,Liu Xuewei,Yang Li et al.Study on the bubble radius and content effect on the acoustic velocity of sea water with bubbles[J].Geoscience,2010,24(3):528-533.