摘要
阿尔茨海默病(AD)是一种常见的中枢神经系统变性疾病,是老年痴呆人群的主要病因。脑源性神经营养因子(BDNF)是神经营养蛋白家族的重要成员。BDNF及其前体蛋白脑源性神经营养因子前体(proBDNF)、脑源性神经营养因子前肽(pBDNF)在AD发病机制中起着重要作用。现对BDNF、proBDNF及pBDNF的表达、功能及其与AD之间的关系进行综述如下。
引文
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