摘要
生物昼夜节律钟基因的发现开创了生物钟研究的新时代。通过对果蝇昼夜节律钟分子机制的研究首次提出了TTFL模型,并在此基础上,通过对其他模式生物尤其是小鼠的研究使该模型得到进一步的发展和完善,对模式生物表型和生理学方面的研究及对模式生物基因克隆的研究,不仅揭示出生物钟演化的过程,而且也展示了科学家对之认识深化的历程。
引文
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