碘131联合射频消融治疗儿童甲状腺功能亢进症伴重度甲状腺肿一例
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摘要
一例12岁8个月女童,发现颈部肿块5年余,喉部不适、呼吸困难一周入院。患儿5年前被诊断为"桥本甲状腺炎、甲状腺功能亢进症",药物治疗后甲状腺功能仍有波动。本次入院后颈部超声检查提示左侧甲状腺大小为8.1 cm×3.2 cm,右侧为8.2 cm×4.8 cm。行碘131联合射频消融治疗后,患儿喉部不适、呼吸困难症状消失,超声检查提示左侧甲状腺缩小至2.3 cm×1.7 cm,右侧缩小至2.8 cm×2.0 cm。随访两年半,无复发。
A 12-year-old girl presented with a history of cervical mass,and one week of throat discomfort and dyspnea.Five years ago,the patient was diagnosed as Hashimoto's thyroiditis and hyperthyroidism;she received antithyroid drug treatment,but the result was not satisfactory.B-ultrasonic showed that the size of thyroid gland was 8.1 cm × 3.2 cm in the left and 8.2 cm × 4.8 cm in the right.After iodine 131 combined with radiofrequency ablation(RFA) treatment,throat discomfort and recumbent breathing difficulties disappeared,and B-ultrasonic showed that the size of thyroid reduced to 2.3 cm × 1.7 cm(left) and 2.8 cm × 2.0 cm(right).No recurrence was observed during the two and a half years of follow-up.
A 12-year-old girl presented with a history of cervical mass,and one week of throat discomfort and dyspnea.Five years ago,the patient was diagnosed as Hashimoto's thyroiditis and hyperthyroidism;she received antithyroid drug treatment,but the result was not satisfactory.B-ultrasonic showed that the size of thyroid gland was 8.1 cm × 3.2 cm in the left and 8.2 cm × 4.8 cm in the right.After iodine 131 combined with radiofrequency ablation(RFA) treatment,throat discomfort and recumbent breathing difficulties disappeared,and B-ultrasonic showed that the size of thyroid reduced to 2.3 cm × 1.7 cm(left) and 2.8 cm × 2.0 cm(right).No recurrence was observed during the two and a half years of follow-up.
引文
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[4]SUNC J Y,BAEK J H,KIM K S,et al.Singlesession treatment of benign cystic thyroid nodules with ethanol versus radiofrequency ablation;a prospective randomized study[J].Radiology,2013,269(1):293-300.
[5]章建全,马娜,徐斌,等.超声引导监测下经皮射频消融甲状腺腺瘤的方法学研究[J].中华超声影像学杂志,2010,19(10):861-865.ZHANG Jianquan,MA Na,XU Bin,et al.Methodology of percutaneous bi-polar radiofrequency ablation of thyroid adenomas under ultrasound guidance and monitoring[J].Chinese Journal of Ultrasonography,2010,19(10):861-865.(in Chinese)
[2]LEGER J,GELWANE G,KAGUEUDOU F,et al.Positive impact of long-term antithyroid drug treatment on the outcome of children with Graves'disease:national long-term cohort study[J].J Clin Endocrinol Metab,2012,97(1).110-]19.
[3]PRASEK K,PLAZINSKA M T,KR6LICKI L.Diagnosis and treatment of Graves'disease with particular emphasis on appropriate techniques in nuclear medicine.General state of knowledge[J].Nucl Med Rev Cent East Eur,2015,18(2):110-116.
[4]SUNC J Y,BAEK J H,KIM K S,et al.Singlesession treatment of benign cystic thyroid nodules with ethanol versus radiofrequency ablation;a prospective randomized study[J].Radiology,2013,269(1):293-300.
[5]章建全,马娜,徐斌,等.超声引导监测下经皮射频消融甲状腺腺瘤的方法学研究[J].中华超声影像学杂志,2010,19(10):861-865.ZHANG Jianquan,MA Na,XU Bin,et al.Methodology of percutaneous bi-polar radiofrequency ablation of thyroid adenomas under ultrasound guidance and monitoring[J].Chinese Journal of Ultrasonography,2010,19(10):861-865.(in Chinese)